(n.) A term formerly restricted to mortification of the soft tissues which has not advanced so far as to produce complete loss of vitality; but now applied to mortification of the soft parts in any stage.
(v. t. & i.) To produce gangrene in; to be affected with gangrene.
Example Sentences:
(1) Clostridium septicum is a bacterial species associated with gas gangrene in both humans and animals.
(2) This paper details the first case report of a patient with fulminant, gangrenous, ischemic colitis caused by polyarteritis nodosa which was successfully treated surgically.
(3) Phenol chemical lumbar sympathectomy is an additional aid in the management of ischaemic rest pain and incipient gangrene.
(4) Most of the patients were delayed cases showing mild to severe degrees of trophic, sensory and motor disturbances in the limbs without gangrene.
(5) Fournier gangrene is a disease which primarily affects adults.
(6) Our experience indicates that the lower gastrointestinal tract should be considered as a possible cause of infection in all cases of synergistic gangrene of the scrotum and penis.
(7) CAA is now thought to play a key role in several multiple etiology disease syndromes; hemorrhagic syndrome; aplastic anemia, gangrenous dermatitis, hemorrhagic anemia syndrome, hemorrhagic aplastic anemia syndrome, anemia dermatitis and blue wing disease.
(8) Two of the three patients (both females) in whom clott migration occured in only one limb developed below-knee gangrene of the affected side.
(9) Patients with sigmoid volvulus with no clinical evidence of gangrene were selected for study, and all were given a trial of non-operative reduction by proctoscopy and passage of a rectal tube.
(10) Acute cholecystitis was found at operation in 33 patients (28%), empyema in nine (7.6%), gangrene of the gallbladder in three (2.5%), and 24 patients (20.3%) were found to have common bile duct stones.
(11) A 28-year-old man developed gangrene of a foot leading to a below-the-knee amputation.
(12) The prognosis was better in patients with gas gangrene after trauma than in patients with gas gangrene resulting from vascular insufficiency or malignant tumours.
(13) Three successfully managed cases of Fournier's gangrene, all with diabetes, are reported.
(14) In six of the ten patients, the presenting complaints were ascribable to incipient gangrene of the toes and several of these patients additionally developed occlusion of tibial and larger arteries while under our observation.
(15) Salient clinical findings in this case include DIC associated with extensive ecchymosis and subsequent gangrene of the skin, thrombotic complications that began on the third day of life.
(16) Lumbar sympathectomy appears to be most beneficial in the management of gangrene of the toe with a limb salvage rate of 75 per cent.
(17) A case is described with multiple gangrene of the fingers of a female, aged 55, with confirmed cirrhosis of liver and diabetes mellitus.
(18) The positive effect of the Defluina-medication on the initial--partly severe--varicose ulcera, with gangrenous alterations, has to be pointed out.
(19) Eleven patients had bacterial gangrene of the foot; two of these patients were less than 23 years of age, and five patients were not known to have had diabetes previously.
(20) Five year cumulative primary patency was 71% overall, 75% in patients with disabling claudication, 61% in those with rest pain and 46% in those with gangrene.
Necrosis
Definition:
(n.) Mortification or gangrene of bone, or the death of a bone or portion of a bone in mass, as opposed to its death by molecular disintegration. See Caries.
(n.) A disease of trees, in which the branches gradually dry up from the bark to the center.
Example Sentences:
(1) After stimulation with lipopolysaccharide and calcium ionophore A23187, culture supernatants of clones c18A and c29A showed cytotoxic activity against human melanoma A375 Met-Mix and other cell lines which were resistant to the tumor necrosis factor, lymphotoxin and interleukin 1.
(2) Ethanol and L-ethionine induce acute steatosis without necrosis, whereas azaserine, carbon tetrachloride, and D-galactosamine are known to produce steatosis with varying degrees of hepatic necrosis.
(3) Light microscopic studies of pancreata from mice sacrificed at this time demonstrated insulitis and beta cell necrosis.
(4) report the complications registered, in particular: lead's displacing 6.2%, run away 0.7%, marked hyperthermya 0.0%, haemorrage 0.4%, wound dehiscence 0.3%, asectic necrosis by decubitus 5%, septic necrosis 0.3%, perforation of the heart 0.2%, pulmonary embolism 0.1%.
(5) Early stabilisation may not ensure normal development but even early splinting carries a small risk of avascular necrosis.
(6) The lesion (10.6 X 9.8 mm) was a well-defined ellipsoid granuloma due to a foreign body with a central zone of necrosis surrounded entirely by a fibrous wall.
(7) In the case presented, overdistension of a jejunostomy catheter balloon led to intestinal obstruction and pressure necrosis (of the small bowel), with subsequent abscess formation leading to death from septicemia.
(8) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
(9) Preincubation of human neutrophils with recombinant tumor necrosis factor alpha has previously been shown by us to enhance superoxide production of neutrophils in response to the chemotactic peptide formyl-methionyl-leucyl-phenylalanine, and the phorbol ester, phorbol myristate acetate.
(10) We studied the chemotaxis of peripheral blood polymorphonuclear leukocytes (PMNs) and monocytes and the production of tumor necrosis factor alpha by monocytes of patients with juvenile periodontitis (JP).
(11) Normal cultured human epidermal melanocytes and melanoma cells derived from three different malignant melanomas were examined for synthesis of extracellular matrix components before and after treatment for one day with interferon-gamma, tumor necrosis factor-alpha, or both.
(12) Diminished CMD was most common with AR (7 of 12) but was also seen with acute tubular necrosis (2 of 6) and cyclosporin toxicity (2 of 3).
(13) Histopathological studies confirmed that mice fed 933cu-rev died from bilateral renal cortical tubular necrosis consistent with toxic insult, perhaps due to Shiga-like toxins.
(14) A constellation of histologic lesions was identified in brain (diffuse meningoencephalitis with bilaterally symmetrical thalamic necrosis), liver (pericholangiohepatitis), lung (pneumonitis), and spleen (lymphoid hyperplasia); this tetrad is apparently unique to this model system.
(15) The authors discuss the results of the diagnosis and treatment of abscesses of the right hepatic lobe which were consequent upon ischemic necrosis; they were encountered after cholecystectomy in 0.15% of cases.
(16) In the univariate life-table analysis, recurrence-free survival was significantly related to age, pTNM category, tumour size, presence of certain growth patterns, tumour necrosis, tumour infiltration in surrounding thyroid tissue and thyroid gland capsule, lymph node metastases, presence of extra-nodal tumour growth and number of positive lymph nodes, whereas only tumour diameter, thyroid gland capsular infiltration and presence of extra-nodal tumour growth remained as significant prognostic factors in the multivariate analysis.
(17) Excessive accumulation of hydrogen ions in the brain may play a pivotal role in initiating the necrosis seen in infarction and following hyperglycemic augmentation of ischemic brain damage.
(18) Histopathological observations demonstrated that OB-5 inhibited the incidence of crescent formation, adhesion and fibrinoid necrosis in the glomeruli by the 41st day.
(19) In 17 patients with femoral neck fractures who were between 15 and 40 years old the incidence of aseptic necrosis in patients followed more than 2 years was 18.7 per cent.
(20) Many of the pathophysiologic effects of bacterial endotoxin have recently been attributed to a monokine, tumor necrosis factor (TNF).