(n.) An opening in anything made by breaking or parting; as, a gap in a fence; an opening for a passage or entrance; an opening which implies a breach or defect; a vacant space or time; a hiatus; a mountain pass.
(v. t.) To notch, as a sword or knife.
(v. t.) To make an opening in; to breach.
Example Sentences:
(1) Linear and annular gap junctions between neighbouring cells were present, particularly in Group 1.
(2) We conclude that removal of dimers and repair of gaps were similar in all cases.
(3) Hence the major role of the 14-A arm of carboxybiotin is not to permit a large carboxyl migration but, rather to permit carboxybiotin to traverse the gap which occurs at the interface of three subunits and to insinuate itself between the CoA and keto acid sites.
(4) The junctional currents were already constant 1 ms after step changes in the junctional voltage; this was three orders of magnitude faster than the other known examples of voltage-controlled gap junctions between embryonic cells.
(5) These two enzymes may act jointly in filling up the gaps along the DNA molecule and elongating the DNA chain.
(6) Preliminary hearing results of 45 cases show air-bone gap closure of 67% within 10 dB and 98% within 20 dB.
(7) Measurements were made of the width of the marginal gap for three sites at each of four stages: (1) after the shoulder firing, (2) after the body-incisal firing, (3) after the glaze firing, and (4) after a correction firing.
(8) Office of National Statistics figures published in November last year showed that men earn 9.4% more than women, the lowest gender gap since records began in 1997.
(9) To a large extent, the failure has been a consequence of a cold war-style deadlock – Russia and Iran on one side, and the west and most of the Arab world on the other – over the fate of Bashar al-Assad , a negotiating gap kept open by force in the shape of massive Russian and Iranian military support to keep the Syrian regime in place.
(10) These activities define both the polarity of the anterior-posterior (AP) axis and the spatial domains of expression of the zygotic gap genes, which in turn control the subsequent steps in segmentation.
(11) After loss of permanent central incisors the treatment of choice could be either orthodontic closure or maintenance of the gap for a replacement-prosthetic, autotransplantation or implant.
(12) PTH, an inducer of shape change, did not affect the number of gap junctions appreciably.
(13) The primary aim of future work must still be directed toward preventing the formation of a gap between the restoration and the tooth.
(14) Since testosterone influenced both tissue stores and PDBu-stimulated secretion of LHRH and GAP, this steroid may selectively regulate biosynthesis and secretion of pro-LHRH-derived peptides through activation of the metabolic cascade involving the PKC system.
(15) Microsequencing of the peptides resolved by sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicates that the amino terminus of the protein is disposed at or near the cytoplasmic surface of the gap junction, and that this surface also contains a protease-hypersensitive hydrophilic sequence between residues 109 and 123, presumably connecting the second and third transmembrane segments.
(16) The present investigation shows that the intramembranous proteins of tight and gap junctions are mobile structures within the fluid membrane.
(17) The report also recommends including justice and victim of violence targets in the national Closing the Gap strategy, recognising foetal alcohol spectrum disorders as a disability before the courts, and making a national commitment to a justice reinvestment approach to find community-based solutions to youth crime.
(18) Regions within the desmosome where the two plasma membranes converged suggested that gap junctions were a component of the desmosome-like junctions.
(19) The frequency of chromosome and chromatid gaps and chromosome deletions was significantly higher among workers than among controls, and the same was true for the number of individuals with some type of chromosome alteration.
(20) Gap junctions were of different sizes and frequently composed of a small number of connexons organized in polygonal aggregates or linear arrays.
Gat
Definition:
() imp. of Get.
() of Get
Example Sentences:
(1) A search for other mutations in N-RAS exon-1 in T-ALL revealed a codon 13 mutation substituting aspartic acid (GAT) for glycine (GGT) in one of 18 patients.
(2) Thus, these data physically verify the serological characteristics of GAT-TsF1 that were originally defined solely on the basis of biological activity.
(3) We found that the cell-associated form of a factor specific for L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT-TsF1) is a 66 kDa protein which exhibits a slightly acidic isoelectric point, but no carbohydrate as determined by enzymatic analysis and lectin-affinity chromatography.
(4) Thus, helper T cells can serve as the cellular target of antigen-specific, MHC-restricted GAT-TsF2, and cloned helper T cells can be used as a homogeneous target population for analysis of the molecular mechanisms of T cell suppression.
(5) The maternal defect was shown to be a frameshift mutation with the deletion of a single T in the aspartic acid codon at position 690 (GAT), 11 amino acids N-terminal to the beginning of the transmembrane domain.
(6) The small inequality tau re gat greater than tau off2 suggests that charges which have returned from immobilization are not immediately available for displacement.
(7) Simultaneous immunization in vivo with the various GAT-Mphi or GAT-MBSA plus soluble GAT modulated the response pattern of these F(1) spleen cells such that they developed secondary responses only to F(1) and parental responder GAT-Mphi regardless of the response pattern observed after immunization with the various GAT-Mphi or GAT-MBSA alone.
(8) Two clonal cell lines, Cl-3 and Cl-7, were cloned from the PC-1 cell line, and these cell lines also carried the GAT point mutation at codon 12.
(9) Body weight was affected by Ea-B, Ir-GAT, and the interaction between Ea-B and Ir-GAT, but not by interaction with RSV response.
(10) The Charity Commission, which has already opened a case against the GAT, has been told of footage obtained by ITV’s Exposure: Charities Behaving Badly documentary.
(11) These results showed that immunization of (responder X responder)F1 mice with parental GAT-M phi results in the development of antigen-specific helper and suppressor T cells.
(12) The Plowell allele was shown in one M3P heterozygous individual to be due to a GAT(Asp) to GTT(Val) change at codon 256, in agreement with a previous study based on hybridization with allele-specific oligonucleotides.
(13) T cell subsets from virgin and immunized mice, which are Ir gene controlled nonresponders to GAT, which regulate antibody responses to GAT have been characterized.
(14) When cultured in the presence of exogenous rIL-2 as a growth factor, GAT-specific Th cell lines secreted mainly IL-4, whereas bacillus Calmette Guérin-specific lines produced predominantly IL-2.
(15) Addition of GAT to cultures of spleen cells from nonresponder mice also prevents development of the GAT-specific PFC responses stimulated by GAT-MBSA.
(16) Anti-idiotypic antisera made against each of the 15 hybridoma anti-GAT antibodies preferentially bound homologous ligand and showed minimal binding activity to specifically purified serum anti-GAT antibodies.
(17) The inequality tau re gat greater than tau re Na was larger and statistically significant at -100 and -110 mV.
(18) Haplotypes with high antibody responses to GAT had significantly higher antibody titers to PM and MG vaccines than haplotypes with low antibody responses.
(19) In contrast, the Th cell line 52.3 used as control could be induced to express high levels of IL2R only after exposure to GAT; nevertheless, IL2 seems to play a critical role in the in vitro survival of the resting state of 52.3 T cells.
(20) These results suggest that posttranslational modification, including glycosylation, is not required for biological activity or for expression of the I-J epitope on the GAT-TsF2 molecule.