(n.) An opening in anything made by breaking or parting; as, a gap in a fence; an opening for a passage or entrance; an opening which implies a breach or defect; a vacant space or time; a hiatus; a mountain pass.
(v. t.) To notch, as a sword or knife.
(v. t.) To make an opening in; to breach.
Example Sentences:
(1) Linear and annular gap junctions between neighbouring cells were present, particularly in Group 1.
(2) We conclude that removal of dimers and repair of gaps were similar in all cases.
(3) Hence the major role of the 14-A arm of carboxybiotin is not to permit a large carboxyl migration but, rather to permit carboxybiotin to traverse the gap which occurs at the interface of three subunits and to insinuate itself between the CoA and keto acid sites.
(4) The junctional currents were already constant 1 ms after step changes in the junctional voltage; this was three orders of magnitude faster than the other known examples of voltage-controlled gap junctions between embryonic cells.
(5) These two enzymes may act jointly in filling up the gaps along the DNA molecule and elongating the DNA chain.
(6) Preliminary hearing results of 45 cases show air-bone gap closure of 67% within 10 dB and 98% within 20 dB.
(7) Measurements were made of the width of the marginal gap for three sites at each of four stages: (1) after the shoulder firing, (2) after the body-incisal firing, (3) after the glaze firing, and (4) after a correction firing.
(8) Office of National Statistics figures published in November last year showed that men earn 9.4% more than women, the lowest gender gap since records began in 1997.
(9) To a large extent, the failure has been a consequence of a cold war-style deadlock – Russia and Iran on one side, and the west and most of the Arab world on the other – over the fate of Bashar al-Assad , a negotiating gap kept open by force in the shape of massive Russian and Iranian military support to keep the Syrian regime in place.
(10) These activities define both the polarity of the anterior-posterior (AP) axis and the spatial domains of expression of the zygotic gap genes, which in turn control the subsequent steps in segmentation.
(11) After loss of permanent central incisors the treatment of choice could be either orthodontic closure or maintenance of the gap for a replacement-prosthetic, autotransplantation or implant.
(12) PTH, an inducer of shape change, did not affect the number of gap junctions appreciably.
(13) The primary aim of future work must still be directed toward preventing the formation of a gap between the restoration and the tooth.
(14) Since testosterone influenced both tissue stores and PDBu-stimulated secretion of LHRH and GAP, this steroid may selectively regulate biosynthesis and secretion of pro-LHRH-derived peptides through activation of the metabolic cascade involving the PKC system.
(15) Microsequencing of the peptides resolved by sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicates that the amino terminus of the protein is disposed at or near the cytoplasmic surface of the gap junction, and that this surface also contains a protease-hypersensitive hydrophilic sequence between residues 109 and 123, presumably connecting the second and third transmembrane segments.
(16) The present investigation shows that the intramembranous proteins of tight and gap junctions are mobile structures within the fluid membrane.
(17) The report also recommends including justice and victim of violence targets in the national Closing the Gap strategy, recognising foetal alcohol spectrum disorders as a disability before the courts, and making a national commitment to a justice reinvestment approach to find community-based solutions to youth crime.
(18) Regions within the desmosome where the two plasma membranes converged suggested that gap junctions were a component of the desmosome-like junctions.
(19) The frequency of chromosome and chromatid gaps and chromosome deletions was significantly higher among workers than among controls, and the same was true for the number of individuals with some type of chromosome alteration.
(20) Gap junctions were of different sizes and frequently composed of a small number of connexons organized in polygonal aggregates or linear arrays.
Lacuna
Definition:
(n.) A small opening; a small pit or depression; a small blank space; a gap or vacancy; a hiatus.
(n.) A small opening; a small depression or cavity; a space, as a vacant space between the cells of plants, or one of the spaces left among the tissues of the lower animals, which serve in place of vessels for the circulation of the body fluids, or the cavity or sac, usually of very small size, in a mucous membrane.
Example Sentences:
(1) Casts of lacunae and canaliculi along with the underlying matrix could be visualized in these preparations.
(2) This kind of distribution of microfilaments was always associated with resorption lacunae, and F-actin, vinculin, and talin zones correspond roughly to the edge of lacunae.
(3) As lacunae develop, both syncytial and cytotrophoblast are exposed to maternal blood.
(4) A cartilage is regarded as 'cell-rich' if its cells or their lacunae occupy more than half of the tissue volume.
(5) Intravenous urography reveals the presence of a persistent lacuna in a calix or of the pelvis, radiologic evidence of the abnormal papilla.
(6) Under the scanning electron microscope, the clear dentine tubules in the resorption lacuna, the shallow, unclear resorption lacuna with deposition of the hard tissue and the various steps between them were observed.
(7) Localised tumour forms present either in the form of large polycyclic lacunae, sometimes invaginated or as vast ulcerations with irregular nodular margin, or as due to parietal infiltration and exoluminal development of the tumour mass and neighbouring adenopathy.
(8) The resorbant organ, rich in odontoclasts, cementoblasts, fibroblasts, and macrophages, formed prominent resorption lacunae in root dentin.
(9) Signs of osteolysis, such as enlarged osteocyte lacunae surrounded by a metachromatic zone in toluidine blue stained sections, and confluence of osteocyte lacunae in microradiographs, were compared with the fluorochrome labelling pattern.
(10) These had networks which formed the floor of each stomata and the roof of each lacunae.
(11) Besides greater detailization of the prevailing diameters of the pores, the method of poremetry allows the information to be obtained concerning the distribution of not only sizes of central canals of osteons but also smaller pores characterizing the system of lacunae of osteocytes and canals connecting them.
(12) Osteocyte viability within the femoral head was assessed by counting empty osteocyte lacunae in five random high-power fields of hematoxylin- and eosin-stained sections.
(13) Lipohyalinosis, initially referred to as the underlying pathologic vascular lesion specific for lacunae, is found most commonly in a subset of patients with severe hypertension associated with multilacunar dementia.
(14) These areas were characterized by a matrix of amorphous blue ground substance with lacunae that contained enlarged and slightly atypical cells.
(15) The condition was diagnosed by biopsy of a cranial bone lacuna.
(16) When ascorbic acid is added to the hormone-supplemented medium, differentiating chondrocytes organize their matrix leading to a cartilage-like structure with hypertrophic chondrocytes embedded in lacunae.
(17) The occlusion of arterioles underneath the site suggests that circulation through the lacunae at this stage is indirect.
(18) The second most common cause of dementia, cerebrovascular disease, produces dementia only when there is destruction of brain tissue, as in individuals who have multiple strokes or who have hypertensive vascular disease leading to multiple lacunae.
(19) Macrophages and giant cells did not form pits or resorption lacunae on the bone substrates as osteoclasts did.
(20) These MNC express an osteoclast phenotype and form resorption lacunae on calcified matrices.