(n.) An opening in anything made by breaking or parting; as, a gap in a fence; an opening for a passage or entrance; an opening which implies a breach or defect; a vacant space or time; a hiatus; a mountain pass.
(v. t.) To notch, as a sword or knife.
(v. t.) To make an opening in; to breach.
Example Sentences:
(1) Linear and annular gap junctions between neighbouring cells were present, particularly in Group 1.
(2) We conclude that removal of dimers and repair of gaps were similar in all cases.
(3) Hence the major role of the 14-A arm of carboxybiotin is not to permit a large carboxyl migration but, rather to permit carboxybiotin to traverse the gap which occurs at the interface of three subunits and to insinuate itself between the CoA and keto acid sites.
(4) The junctional currents were already constant 1 ms after step changes in the junctional voltage; this was three orders of magnitude faster than the other known examples of voltage-controlled gap junctions between embryonic cells.
(5) These two enzymes may act jointly in filling up the gaps along the DNA molecule and elongating the DNA chain.
(6) Preliminary hearing results of 45 cases show air-bone gap closure of 67% within 10 dB and 98% within 20 dB.
(7) Measurements were made of the width of the marginal gap for three sites at each of four stages: (1) after the shoulder firing, (2) after the body-incisal firing, (3) after the glaze firing, and (4) after a correction firing.
(8) Office of National Statistics figures published in November last year showed that men earn 9.4% more than women, the lowest gender gap since records began in 1997.
(9) To a large extent, the failure has been a consequence of a cold war-style deadlock – Russia and Iran on one side, and the west and most of the Arab world on the other – over the fate of Bashar al-Assad , a negotiating gap kept open by force in the shape of massive Russian and Iranian military support to keep the Syrian regime in place.
(10) These activities define both the polarity of the anterior-posterior (AP) axis and the spatial domains of expression of the zygotic gap genes, which in turn control the subsequent steps in segmentation.
(11) After loss of permanent central incisors the treatment of choice could be either orthodontic closure or maintenance of the gap for a replacement-prosthetic, autotransplantation or implant.
(12) PTH, an inducer of shape change, did not affect the number of gap junctions appreciably.
(13) The primary aim of future work must still be directed toward preventing the formation of a gap between the restoration and the tooth.
(14) Since testosterone influenced both tissue stores and PDBu-stimulated secretion of LHRH and GAP, this steroid may selectively regulate biosynthesis and secretion of pro-LHRH-derived peptides through activation of the metabolic cascade involving the PKC system.
(15) Microsequencing of the peptides resolved by sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicates that the amino terminus of the protein is disposed at or near the cytoplasmic surface of the gap junction, and that this surface also contains a protease-hypersensitive hydrophilic sequence between residues 109 and 123, presumably connecting the second and third transmembrane segments.
(16) The present investigation shows that the intramembranous proteins of tight and gap junctions are mobile structures within the fluid membrane.
(17) The report also recommends including justice and victim of violence targets in the national Closing the Gap strategy, recognising foetal alcohol spectrum disorders as a disability before the courts, and making a national commitment to a justice reinvestment approach to find community-based solutions to youth crime.
(18) Regions within the desmosome where the two plasma membranes converged suggested that gap junctions were a component of the desmosome-like junctions.
(19) The frequency of chromosome and chromatid gaps and chromosome deletions was significantly higher among workers than among controls, and the same was true for the number of individuals with some type of chromosome alteration.
(20) Gap junctions were of different sizes and frequently composed of a small number of connexons organized in polygonal aggregates or linear arrays.
Sap
Definition:
(n.) The juice of plants of any kind, especially the ascending and descending juices or circulating fluid essential to nutrition.
(n.) The sapwood, or alburnum, of a tree.
(n.) A simpleton; a saphead; a milksop.
(v. t.) To subvert by digging or wearing away; to mine; to undermine; to destroy the foundation of.
(v. t.) To pierce with saps.
(v. t.) To make unstable or infirm; to unsettle; to weaken.
(v. i.) To proceed by mining, or by secretly undermining; to execute saps.
(n.) A narrow ditch or trench made from the foremost parallel toward the glacis or covert way of a besieged place by digging under cover of gabions, etc.
Example Sentences:
(1) By contrast, SAP-35, the major surfactant-associated glycoprotein of molecular weight = 35,000, and other higher molecular weight proteins were not detected in significant quantities in the CLSE or surfactant-TA replacement surfactants, either by highly sensitive silver stain analysis or by immunoblot using monospecific antisera generated against bovine SAP-35.
(2) In normovolemia, the hepatic arterial flow (HAF) increased as the systemic arterial pressure (SAP) rose up to 140 mmHg, and then decreased as SAP rose further.
(3) Rat type II pneumocytes expressed vitamin K-dependent carboxylase activity that incorporated 14CO2 into microsomal protein precursors of molecular weights similar to those of surfactant-associated proteins (SAP).
(4) At this SAP a constant amount of SNP and 500 ml Dextran 60 were infused.
(5) The in vitro transcript probes could detect 1 ng of purified virus and as little as 1 microliter of sap extracts prepared from infected oat shoots.
(6) Combined propranolol-atropine blockade increased heart rate at rest in the SAP state, and significantly attenuated the tachycardia accompanying treadmill exercise.
(7) It is concluded that the cell sap from rat liver contains the complete set of enzymes for the synthesis from delta-aminolaevulinate of haem c and its linkage to a small pool of free apoprotein c present in soluble form.
(8) As shown earlier, at zero turgor pressure the intracellular freezing point of the parenchyma cells matches closely the negative pressure in the xylem sap.
(9) Whole blood components did not interfere with the efficacy of OKT1-SAP, as in vitro treatment of fresh whole blood resulted in effective elimination of clonable peripheral blood T-lymphocytes assessed by a limiting dilution assay.
(10) According to the theory of osmoelastic coupling, also large additives, such as the proteins of the cell sap, are able to cause an osmotic stress equivalent to that caused by polyethylene glycol.
(11) SAP did not bind to the macrophage cell line RAW264.7 nor did it enhance IL-1 secretion by this line.
(12) The cell sap in the absence of ribosomes was also able to incorporate radioactivity into purified cytochrome c, and the addition of ribosomes significantly enhanced the activity.
(13) The C4BP.SAP complex was also detected in normal serum and the results suggested that there was virtually no free SAP or uncomplexed C4BP in normal serum.
(14) An additional category, SAP "flare", was also identified (SAP increment greater than 15% at 1 month, with subsequent fall at 2 months).
(15) The biophysical activity of synthetic phospholipid-apoprotein combinants was assessed by measurements of adsorption facility and dynamic surface tension lowering ability at 37 degrees C. The SM-SAP-6 combinants had adsorption facility equivalent to natural lung surfactant, and to the surfactant extract preparations CLSE and surfactant-TA used in exogenous surfactant replacement therapy for the neonatal Respiratory Distress Syndrome (RDS).
(16) Histone phosphorylation is sharply inhibited after addition of DNA, the protein kinases of nuclear sap phosphorylating less effectively the histones complexed with DNA than the non-histone proteins.
(17) Specific SAP-35 RNA increased during organ culture and both SAP-35 content and SAP-35 RNA increased in the absence of exogenous hormones in 2% carbon-stripped fetal calf serum.
(18) The beta2-microglobulin in the cell-sap fraction was present in the unbound state.
(19) No patients at risk for developing heterotopic bone after THA could be identified from the preoperative level of SAP.
(20) The mass of SAP in these was determined from the extinction coefficient of SAP at 280 nm measured here precisely for the first time by spectrophotometry and cryogenic drying.