(v.) Any slender marine fish of the genera Belone and Tylosurus. See Garfish.
(v.) The gar pike. See Alligator gar (under Alligator), and Gar pike.
(n.) To cause; to make.
Example Sentences:
(1) The IDIR terminal sequences and those of group A rotaviruses (GAR) were similar in that each of the (+) strands began with "GG" and ended with "CC."
(2) Retinal projections were studied with autoradiographic and silver methods in the gar, Lepisosteus osseus, one of the two surviving members of the holostean actinopterygians.
(3) Chinese hamster ovary (CHO) cell mutant purine auxotrophs deficient in GAR synthetase (Ade-C) or AIR synthetase plus GAR transformylase (Ade-G) activities were transfected with this human GART cDNA subcloned into a mammalian expression vector.
(4) We have found that the antifolates methotrexate (MTX) and piritrexim (PTX) completely block the de novo purine pathway in mouse L1210 leukemia cells growing in culture but with only minor accumulations of GAR and AICAR to less than 5% of the polyphosphate derivatives of N-formylglycinamide ribotide (FGAR) which accumulate when the pathway is blocked completely by azaserine.
(5) In tests against other folate-utilizing enzymes, 11a and 11b were found to be inhibitors of glycinamide ribonucleotide formyltransferase (GAR formyltransferase) from one bacterial (Lactobacillus casei) and two mammalian (Manca and L1210) sources with 11a being decidedly more inhibitory than 11b.
(6) The depression of hepatic glycinamide ribotide (GAR) transformylase in rats exposed to nitrous oxide was prevented by supplying a formate precursor, methylthioadenosine.
(7) 10-Formyl-H2folate-Glu5 was a competitive inhibitor of thymidylate synthase (Ki = 0.16 microM with 5,10-methylene-H4folate-Glu1 as substrate and 1.6 microM with 5,10-methylene-H4folate-Glu5) and inhibited GAR transformylase (Ki = 2.0 microM).
(8) Anomerization occurs upon removing the O-isopropylidene group from either 7 or 8, so that the final compound (10) is an equimolar mixture of both anomers, of which only one is active toward GAR-transformylase.
(9) This restored 49-140% of the activities of GAR synthetase, AIR synthetase, and GAR transformylase in transfected cells when compared to wild-type CHO K1 parental cells.
(10) The oxyntomodulin contains 36 amino acid residues and its sequence is H S Q G T F T N D Y S K Y L D T R R A Q D F V Q W L M S T K R S G G I T. The composition of the glucagon is identical to the N-terminal 29 residues of the gar oxyntomodulin.
(11) The gene is functional when YAC DNA is transferred into GARS- or GARS-and-AIRS-deficient Chinese Hamster Ovary cells.
(12) The lateral-line system of gars consists of superficial neuromasts, which are arranged in lines termed pit lines, canal neuromasts and spiracular organs, which are located within diverticula of the hyoid gill pouch.
(13) Characterization of the chemical stability of PRA and Kequi for ribose-5-phosphate, NH3 with PRA will now allow detailed kinetic analysis of the newly discovered trifunctional protein containing GAR synthetase activity in addition to AIR synthetase and GAR transformylase activities.
(14) The avidin-biotin system was also useful, but somewhat less sensitive than GAR-enzyme conjugates.
(15) Similar results were also obtained for KBD estimation using the Garred model and KBD estimated during dialysate isovolaemia.
(16) Untreated, resuced and alkylated, S-sulfonated, or cyanogen bromide cleaved macroglobulin from the gar (Lepisosteus osseus) contained no polypeptide analogous to either catfish or human J chain by the criteria employed in this study.
(17) I suspect that messrs Fry and Connolly – who grew up watching this man segue from gar- landed stage-thesp to tireless campaigner (Stonewall, women's and children's rights) to Hollywood catnip to that dreadful position for anyone with a fine remaining sense of mischief: being on the cusp of national-treasure status – were equally conscious of the company they were in.
(18) The choleretic action of SSM-G was milder, but longer lasting than those of GAR-G and DAM-G.
(19) Using these hybrids along with another independently constructed hybrid, the GAR synthetase gene was mapped distal to SOD-1 and proximal to CP21G1(D21S60).
(20) Glycinamide ribonucleotide synthetase and GAR transformylase were separable only after exposure to chymotrypsin.
Gat
Definition:
() imp. of Get.
() of Get
Example Sentences:
(1) A search for other mutations in N-RAS exon-1 in T-ALL revealed a codon 13 mutation substituting aspartic acid (GAT) for glycine (GGT) in one of 18 patients.
(2) Thus, these data physically verify the serological characteristics of GAT-TsF1 that were originally defined solely on the basis of biological activity.
(3) We found that the cell-associated form of a factor specific for L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT-TsF1) is a 66 kDa protein which exhibits a slightly acidic isoelectric point, but no carbohydrate as determined by enzymatic analysis and lectin-affinity chromatography.
(4) Thus, helper T cells can serve as the cellular target of antigen-specific, MHC-restricted GAT-TsF2, and cloned helper T cells can be used as a homogeneous target population for analysis of the molecular mechanisms of T cell suppression.
(5) The maternal defect was shown to be a frameshift mutation with the deletion of a single T in the aspartic acid codon at position 690 (GAT), 11 amino acids N-terminal to the beginning of the transmembrane domain.
(6) The small inequality tau re gat greater than tau off2 suggests that charges which have returned from immobilization are not immediately available for displacement.
(7) Simultaneous immunization in vivo with the various GAT-Mphi or GAT-MBSA plus soluble GAT modulated the response pattern of these F(1) spleen cells such that they developed secondary responses only to F(1) and parental responder GAT-Mphi regardless of the response pattern observed after immunization with the various GAT-Mphi or GAT-MBSA alone.
(8) Two clonal cell lines, Cl-3 and Cl-7, were cloned from the PC-1 cell line, and these cell lines also carried the GAT point mutation at codon 12.
(9) Body weight was affected by Ea-B, Ir-GAT, and the interaction between Ea-B and Ir-GAT, but not by interaction with RSV response.
(10) The Charity Commission, which has already opened a case against the GAT, has been told of footage obtained by ITV’s Exposure: Charities Behaving Badly documentary.
(11) These results showed that immunization of (responder X responder)F1 mice with parental GAT-M phi results in the development of antigen-specific helper and suppressor T cells.
(12) The Plowell allele was shown in one M3P heterozygous individual to be due to a GAT(Asp) to GTT(Val) change at codon 256, in agreement with a previous study based on hybridization with allele-specific oligonucleotides.
(13) T cell subsets from virgin and immunized mice, which are Ir gene controlled nonresponders to GAT, which regulate antibody responses to GAT have been characterized.
(14) When cultured in the presence of exogenous rIL-2 as a growth factor, GAT-specific Th cell lines secreted mainly IL-4, whereas bacillus Calmette Guérin-specific lines produced predominantly IL-2.
(15) Addition of GAT to cultures of spleen cells from nonresponder mice also prevents development of the GAT-specific PFC responses stimulated by GAT-MBSA.
(16) Anti-idiotypic antisera made against each of the 15 hybridoma anti-GAT antibodies preferentially bound homologous ligand and showed minimal binding activity to specifically purified serum anti-GAT antibodies.
(17) The inequality tau re gat greater than tau re Na was larger and statistically significant at -100 and -110 mV.
(18) Haplotypes with high antibody responses to GAT had significantly higher antibody titers to PM and MG vaccines than haplotypes with low antibody responses.
(19) In contrast, the Th cell line 52.3 used as control could be induced to express high levels of IL2R only after exposure to GAT; nevertheless, IL2 seems to play a critical role in the in vitro survival of the resting state of 52.3 T cells.
(20) These results suggest that posttranslational modification, including glycosylation, is not required for biological activity or for expression of the I-J epitope on the GAT-TsF2 molecule.