(v.) Any slender marine fish of the genera Belone and Tylosurus. See Garfish.
(v.) The gar pike. See Alligator gar (under Alligator), and Gar pike.
(n.) To cause; to make.
Example Sentences:
(1) The IDIR terminal sequences and those of group A rotaviruses (GAR) were similar in that each of the (+) strands began with "GG" and ended with "CC."
(2) Retinal projections were studied with autoradiographic and silver methods in the gar, Lepisosteus osseus, one of the two surviving members of the holostean actinopterygians.
(3) Chinese hamster ovary (CHO) cell mutant purine auxotrophs deficient in GAR synthetase (Ade-C) or AIR synthetase plus GAR transformylase (Ade-G) activities were transfected with this human GART cDNA subcloned into a mammalian expression vector.
(4) We have found that the antifolates methotrexate (MTX) and piritrexim (PTX) completely block the de novo purine pathway in mouse L1210 leukemia cells growing in culture but with only minor accumulations of GAR and AICAR to less than 5% of the polyphosphate derivatives of N-formylglycinamide ribotide (FGAR) which accumulate when the pathway is blocked completely by azaserine.
(5) In tests against other folate-utilizing enzymes, 11a and 11b were found to be inhibitors of glycinamide ribonucleotide formyltransferase (GAR formyltransferase) from one bacterial (Lactobacillus casei) and two mammalian (Manca and L1210) sources with 11a being decidedly more inhibitory than 11b.
(6) The depression of hepatic glycinamide ribotide (GAR) transformylase in rats exposed to nitrous oxide was prevented by supplying a formate precursor, methylthioadenosine.
(7) 10-Formyl-H2folate-Glu5 was a competitive inhibitor of thymidylate synthase (Ki = 0.16 microM with 5,10-methylene-H4folate-Glu1 as substrate and 1.6 microM with 5,10-methylene-H4folate-Glu5) and inhibited GAR transformylase (Ki = 2.0 microM).
(8) Anomerization occurs upon removing the O-isopropylidene group from either 7 or 8, so that the final compound (10) is an equimolar mixture of both anomers, of which only one is active toward GAR-transformylase.
(9) This restored 49-140% of the activities of GAR synthetase, AIR synthetase, and GAR transformylase in transfected cells when compared to wild-type CHO K1 parental cells.
(10) The oxyntomodulin contains 36 amino acid residues and its sequence is H S Q G T F T N D Y S K Y L D T R R A Q D F V Q W L M S T K R S G G I T. The composition of the glucagon is identical to the N-terminal 29 residues of the gar oxyntomodulin.
(11) The gene is functional when YAC DNA is transferred into GARS- or GARS-and-AIRS-deficient Chinese Hamster Ovary cells.
(12) The lateral-line system of gars consists of superficial neuromasts, which are arranged in lines termed pit lines, canal neuromasts and spiracular organs, which are located within diverticula of the hyoid gill pouch.
(13) Characterization of the chemical stability of PRA and Kequi for ribose-5-phosphate, NH3 with PRA will now allow detailed kinetic analysis of the newly discovered trifunctional protein containing GAR synthetase activity in addition to AIR synthetase and GAR transformylase activities.
(14) The avidin-biotin system was also useful, but somewhat less sensitive than GAR-enzyme conjugates.
(15) Similar results were also obtained for KBD estimation using the Garred model and KBD estimated during dialysate isovolaemia.
(16) Untreated, resuced and alkylated, S-sulfonated, or cyanogen bromide cleaved macroglobulin from the gar (Lepisosteus osseus) contained no polypeptide analogous to either catfish or human J chain by the criteria employed in this study.
(17) I suspect that messrs Fry and Connolly – who grew up watching this man segue from gar- landed stage-thesp to tireless campaigner (Stonewall, women's and children's rights) to Hollywood catnip to that dreadful position for anyone with a fine remaining sense of mischief: being on the cusp of national-treasure status – were equally conscious of the company they were in.
(18) The choleretic action of SSM-G was milder, but longer lasting than those of GAR-G and DAM-G.
(19) Using these hybrids along with another independently constructed hybrid, the GAR synthetase gene was mapped distal to SOD-1 and proximal to CP21G1(D21S60).
(20) Glycinamide ribonucleotide synthetase and GAR transformylase were separable only after exposure to chymotrypsin.
Gnar
Definition:
(n.) A knot or gnarl in wood; hence, a tough, thickset man; -- written also gnarr.
(v. i.) To gnarl; to snarl; to growl; -- written also gnarr.
Example Sentences:
(1) Then there's a figure like Bassnectar, who can play the big carnival-style festivals but also takes his gnarly-but-trippy version of dubstep to events like Electric Forest, where he'll play on the same bill as jam bands like String Cheese Incident.
(2) She began as a ringletted country singer, teenage sweetheart of the American heartland, but between 2006’s eponymous first album and now she’s become the kind of culturally titanic figure adored as much by gnarly rock critics as teenage girls, feminist intellectuals and, well, pretty much all of emotionally sentient humankind.
(3) Bowie broke the silence in 2013 with The Next Day , a gnarly rock album spitting anger at warmongers, zombie celebrities and The Reaper with equal venom, as he prepares to “stumble to the graveyard and lay down by my parents”, adding archly, “just remember duckies, everybody gets got”.
(4) 9.59am GMT “This slopestyle is , as the kids say, gnarly,” says Guy Hornsby.
(5) Singer-guitarist Dan Auerbach and drummer Pat Carney are sitting side by side in a booth, scoffing cheeseburgers while appreciating the gathering of gnarly boozers at the jukebox in the corner.
(6) Pursuing his father's Italian roots he lived there for three years learning to cook, and the food he serves - a lot of offal, sweet and sour sauces for meats, gnarly rustic pasta dishes - is, he says, the antithesis of the ersatz version of Italian served in New York's old-fashioned red-sauce restaurants.
(7) Replacement of the signal recognition particle (SRP) 7S gene (SCR1) on a replicating plasmid with scr1-1 (G to A at 129 and A to T at 131 in the consensus sequence -GNAR- in the loop of domain III) resulted in temperature sensitivity for growth of cells in which both chromosomal SRP 7S RNA genes were deleted.
(8) They are primary RNA binding proteins, recognize RNA tetranucleotide loops with a GNAR consensus motif, and require a helical region located adjacent to the tetraloop.
(9) This old chestnut has raised its gnarly weather-beaten head more than once since our plea for seasonally themed questions.
(10) Grid reference: 51.3001, 1.1513 Photograph: www.wildswimming.com Kailpot Crag, Ullswater, Lake District Ullswater is one of the most popular and beautiful lakes in the Lake District, but to escape the crowds head for this high, gnarly crag.
(11) "Some gnarly jocks were trying to hump up on the girls," says Korine.
(12) Shoppers could and do argue that their waste is spurred by supermarket offers; farmers could and do argue that their waste is caused by factors outside their control, such as: "I cannot eat this parsnip because it looks like the gnarly hand of a wizard."
(13) Stay sick, my friends, no seriously, I'm liveblogging today with a pretty gnarly cold, but I also promise to make it through all of this game.
(14) He is also the only sound editor the Coen Brothers work with, which means that he is the person responsible for that gnarly wood chipper noise in Fargo, the peel of wallpaper in Barton Fink, the resonance of The Dude’s bowling ball in The Big Lebowski and the absolutely chilling crinkle of Javier Bardem’s gum wrapper in No Country for Old Men.
(15) "It's just so… gnarly," he tells the team in the footage from that time.
(16) We thought if we both get pregnant, well, that's a bit gnarly, but we can ride it out.
(17) 11.02am GMT “On the more, er ... gnarly events, the commentary should go the full WWE,” says Gary Naylor.
(18) I'd say to Russell, 'Oh try this…'" The turning point was when she nailed a gnarly Venetian staple called baccalà mantecato .
(19) Click here to watch There was a notable absence of rock at this year's Grammys, but thankfully Nine Inch Nails' Trent Reznor took centre stage for the gnarly closer, performing Copy of A from his 2013 album Hesitation Marks, joined on stage by Fleetwood Mac's Lindsey Buckingham, Dave Grohl and Josh Homme.
(20) The upstairs rooms have sweeping views of the dense urban environment, while the pretty garden of potted flowers and gnarly old trees provides a welcome escape from it.