(v.) Any slender marine fish of the genera Belone and Tylosurus. See Garfish.
(v.) The gar pike. See Alligator gar (under Alligator), and Gar pike.
(n.) To cause; to make.
Example Sentences:
(1) The IDIR terminal sequences and those of group A rotaviruses (GAR) were similar in that each of the (+) strands began with "GG" and ended with "CC."
(2) Retinal projections were studied with autoradiographic and silver methods in the gar, Lepisosteus osseus, one of the two surviving members of the holostean actinopterygians.
(3) Chinese hamster ovary (CHO) cell mutant purine auxotrophs deficient in GAR synthetase (Ade-C) or AIR synthetase plus GAR transformylase (Ade-G) activities were transfected with this human GART cDNA subcloned into a mammalian expression vector.
(4) We have found that the antifolates methotrexate (MTX) and piritrexim (PTX) completely block the de novo purine pathway in mouse L1210 leukemia cells growing in culture but with only minor accumulations of GAR and AICAR to less than 5% of the polyphosphate derivatives of N-formylglycinamide ribotide (FGAR) which accumulate when the pathway is blocked completely by azaserine.
(5) In tests against other folate-utilizing enzymes, 11a and 11b were found to be inhibitors of glycinamide ribonucleotide formyltransferase (GAR formyltransferase) from one bacterial (Lactobacillus casei) and two mammalian (Manca and L1210) sources with 11a being decidedly more inhibitory than 11b.
(6) The depression of hepatic glycinamide ribotide (GAR) transformylase in rats exposed to nitrous oxide was prevented by supplying a formate precursor, methylthioadenosine.
(7) 10-Formyl-H2folate-Glu5 was a competitive inhibitor of thymidylate synthase (Ki = 0.16 microM with 5,10-methylene-H4folate-Glu1 as substrate and 1.6 microM with 5,10-methylene-H4folate-Glu5) and inhibited GAR transformylase (Ki = 2.0 microM).
(8) Anomerization occurs upon removing the O-isopropylidene group from either 7 or 8, so that the final compound (10) is an equimolar mixture of both anomers, of which only one is active toward GAR-transformylase.
(9) This restored 49-140% of the activities of GAR synthetase, AIR synthetase, and GAR transformylase in transfected cells when compared to wild-type CHO K1 parental cells.
(10) The oxyntomodulin contains 36 amino acid residues and its sequence is H S Q G T F T N D Y S K Y L D T R R A Q D F V Q W L M S T K R S G G I T. The composition of the glucagon is identical to the N-terminal 29 residues of the gar oxyntomodulin.
(11) The gene is functional when YAC DNA is transferred into GARS- or GARS-and-AIRS-deficient Chinese Hamster Ovary cells.
(12) The lateral-line system of gars consists of superficial neuromasts, which are arranged in lines termed pit lines, canal neuromasts and spiracular organs, which are located within diverticula of the hyoid gill pouch.
(13) Characterization of the chemical stability of PRA and Kequi for ribose-5-phosphate, NH3 with PRA will now allow detailed kinetic analysis of the newly discovered trifunctional protein containing GAR synthetase activity in addition to AIR synthetase and GAR transformylase activities.
(14) The avidin-biotin system was also useful, but somewhat less sensitive than GAR-enzyme conjugates.
(15) Similar results were also obtained for KBD estimation using the Garred model and KBD estimated during dialysate isovolaemia.
(16) Untreated, resuced and alkylated, S-sulfonated, or cyanogen bromide cleaved macroglobulin from the gar (Lepisosteus osseus) contained no polypeptide analogous to either catfish or human J chain by the criteria employed in this study.
(17) I suspect that messrs Fry and Connolly – who grew up watching this man segue from gar- landed stage-thesp to tireless campaigner (Stonewall, women's and children's rights) to Hollywood catnip to that dreadful position for anyone with a fine remaining sense of mischief: being on the cusp of national-treasure status – were equally conscious of the company they were in.
(18) The choleretic action of SSM-G was milder, but longer lasting than those of GAR-G and DAM-G.
(19) Using these hybrids along with another independently constructed hybrid, the GAR synthetase gene was mapped distal to SOD-1 and proximal to CP21G1(D21S60).
(20) Glycinamide ribonucleotide synthetase and GAR transformylase were separable only after exposure to chymotrypsin.
Lar
Definition:
(n.) A tutelary deity; a deceased ancestor regarded as a protector of the family. The domestic Lares were the tutelar deities of a house; household gods. Hence, Eng.: Hearth or dwelling house.
(n.) A species of gibbon (Hylobates lar), found in Burmah. Called also white-handed gibbon.
Example Sentences:
(1) We conclude that both exogenously applied PAF by inhalation and antigen exposure are capable of inducing LAR in sensitized guinea pigs, and thus the priming effect of immunization and PAF may contribute to the development of LAR observed in asthma.
(2) A Swedish news agency said it had received an email warning before the blasts in which a threat was made against Sweden's population, linked to the country's military presence in Afghanistan and the five-year-old case of caricatures of the prophet Muhammad by Swedish artist Lars Vilks.
(3) Substitutes: Andoni Zubizarreta (Spain), Lajos Detari (Hungary), Dragan Stojkovic (Yugoslavia), Igor Belanov (USSR), Preben Elkjær Larsen (Denmark), Lars Larsson (Sweden), Alexandre Zavarov (USSR).
(4) The concentration of the eosinophil cationic protein (ECP) in their sputum did not change significantly in IAR and LAR compared with that before antigen challenge.
(5) Antonio Conte Vicente del Bosque Lars Lagerbäck Didier Deschamps Conte's Italy lost to Deschamps's France in the Euro 2000 final.
(6) Employing an animal model of the LAR in rabbits developed in our laboratory (Am Rev Respir Dis 1982; 126:493-498), we examined changes in airway reactivity and pulmonary inflammation in rabbits having a late asthmatic response.
(7) The late asthmatic response (LAR) is of special interest because it lasts for hours, is prevented by corticosteroids and not adrenergic agents, and is associated with more severe asthma as well as increases in airways responsiveness.
(8) A study of the effects of monthly administration of bromocriptine LAR is currently under progress to assess the long-term efficacy of this drug.
(9) By including the gamma 1- and gamma 2-globin gene sequences from the common gibbon, Hylobates lar, the present work expands the gamma-globin data set to represent all major groups of hominoid primates.
(10) Another group of investigators assume that non-specific hyperreactivity could contribute to the development of the LAR.
(11) All eight temperature-sensitive mutations are confined within a short segment of the LAR domain I sequence between amino acid positions 1329 and 1407.
(12) Spotify has been courting established artists for some time, with Metallica’s Lars Ulrich famously buddying up with Spotify investor Sean Parker on-stage at the announcement of his band’s exclusive deal in December 2012.
(13) Each individual was pretreated with either placebo or four inhalant anti-asthmatic drugs at random and blind in order to modulate the late asthmatic reaction (LAR).
(14) They adhered to and, when capacitated, penetrated the vestments of the oocyte of an ape--the gibbon, Hylobates lar--both in vivo and in vitro.
(15) In order to investigate the mechanism of late asthmatic response (LAR), inhibitory effects of various drugs for LAR were examined in two wheat flour-sensitive asthmatic subjects who showed immediate and late responses in the allergen provocation test and skin test.
(16) These results suggest that anti-IgE antibody is deeply involved in the elicitation of LAR, stressing the importance of eosinophilic infiltration.
(17) We have now examined whether exogenously applied PAF causes LAR in these models in vivo.
(18) After removal of the rectal lesion [eight abdominoperineal resections (APRs), nine Hartmann's procedures, and one low anterior resection (LAR)] in 18 patients with rectal cancer, this new surgical procedure was performed.
(19) LAR to Parietaria occurred in only one of 12 patients in winter, in six of 11 in summer, and in one of six patients in autumn.
(20) Although these alterations in reactivity have been proposed to be associated with inflammation, no clinical study of the LAR has shown both increased airway reactivity and evidence of pulmonary inflammation.