(1) A search for other mutations in N-RAS exon-1 in T-ALL revealed a codon 13 mutation substituting aspartic acid (GAT) for glycine (GGT) in one of 18 patients.
(2) Thus, these data physically verify the serological characteristics of GAT-TsF1 that were originally defined solely on the basis of biological activity.
(3) We found that the cell-associated form of a factor specific for L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT-TsF1) is a 66 kDa protein which exhibits a slightly acidic isoelectric point, but no carbohydrate as determined by enzymatic analysis and lectin-affinity chromatography.
(4) Thus, helper T cells can serve as the cellular target of antigen-specific, MHC-restricted GAT-TsF2, and cloned helper T cells can be used as a homogeneous target population for analysis of the molecular mechanisms of T cell suppression.
(5) The maternal defect was shown to be a frameshift mutation with the deletion of a single T in the aspartic acid codon at position 690 (GAT), 11 amino acids N-terminal to the beginning of the transmembrane domain.
(6) The small inequality tau re gat greater than tau off2 suggests that charges which have returned from immobilization are not immediately available for displacement.
(7) Simultaneous immunization in vivo with the various GAT-Mphi or GAT-MBSA plus soluble GAT modulated the response pattern of these F(1) spleen cells such that they developed secondary responses only to F(1) and parental responder GAT-Mphi regardless of the response pattern observed after immunization with the various GAT-Mphi or GAT-MBSA alone.
(8) Two clonal cell lines, Cl-3 and Cl-7, were cloned from the PC-1 cell line, and these cell lines also carried the GAT point mutation at codon 12.
(9) Body weight was affected by Ea-B, Ir-GAT, and the interaction between Ea-B and Ir-GAT, but not by interaction with RSV response.
(10) The Charity Commission, which has already opened a case against the GAT, has been told of footage obtained by ITV’s Exposure: Charities Behaving Badly documentary.
(11) These results showed that immunization of (responder X responder)F1 mice with parental GAT-M phi results in the development of antigen-specific helper and suppressor T cells.
(12) The Plowell allele was shown in one M3P heterozygous individual to be due to a GAT(Asp) to GTT(Val) change at codon 256, in agreement with a previous study based on hybridization with allele-specific oligonucleotides.
(13) T cell subsets from virgin and immunized mice, which are Ir gene controlled nonresponders to GAT, which regulate antibody responses to GAT have been characterized.
(14) When cultured in the presence of exogenous rIL-2 as a growth factor, GAT-specific Th cell lines secreted mainly IL-4, whereas bacillus Calmette Guérin-specific lines produced predominantly IL-2.
(15) Addition of GAT to cultures of spleen cells from nonresponder mice also prevents development of the GAT-specific PFC responses stimulated by GAT-MBSA.
(16) Anti-idiotypic antisera made against each of the 15 hybridoma anti-GAT antibodies preferentially bound homologous ligand and showed minimal binding activity to specifically purified serum anti-GAT antibodies.
(17) The inequality tau re gat greater than tau re Na was larger and statistically significant at -100 and -110 mV.
(18) Haplotypes with high antibody responses to GAT had significantly higher antibody titers to PM and MG vaccines than haplotypes with low antibody responses.
(19) In contrast, the Th cell line 52.3 used as control could be induced to express high levels of IL2R only after exposure to GAT; nevertheless, IL2 seems to play a critical role in the in vitro survival of the resting state of 52.3 T cells.
(20) These results suggest that posttranslational modification, including glycosylation, is not required for biological activity or for expression of the I-J epitope on the GAT-TsF2 molecule.
Guitar
Definition:
(n.) A stringed instrument of music resembling the lute or the violin, but larger, and having six strings, three of silk covered with silver wire, and three of catgut, -- played upon with the fingers.
Example Sentences:
(1) He's finding solace, fleeting and fragmentary, and every springy guitar lick is its own benediction," Chinen wrote.
(2) There is Ed Sheeran , with a guitar and loop pedal, and Chris Martin leaping around the stage with the rest of Coldplay providing a dourer backdrop.
(3) Out of the seabird whoops and thrashing drumming of the intro to Endangered Species come guitar-sax exchanges that sound like Prime Time’s seething fusion soundscapes made illuminatingly clearer.
(4) While there's no discernible forró influence in the dreamy 80s indie-guitar music of Fortaleza's Cidadão Instigado, they do take influence from popular local style brega, a 1970s and 80s Brazilian romantic pop music.
(5) Danielle thudded out a bass beat, somehow keeping her guitar baying at the same time.
(6) "A new generation picking up guitars and drums and saying, 'I'm here!
(7) Unlike many music hack days, this is a commercial contest: the winning hack – as judged by Slash, BitTorrent founder Bram Cohen and investor Ben Parr – will earn its creator an autographed guitar, $1,000 and “the chance to have Slash use the winning hack with the release of his new album”.
(8) • The guitar, along with flamenco's signature cry of olé, are believed to be derived from early versions of the instruments brought by the Muslims to Spain.
(9) We went in September and found an annual three-week-long international guitar festival under way.
(10) I know you love me and I love you,” said Jonathan, wearing his trademark fedora and carrying a gold-handled cane, in a speech punctuated by bass guitar and cymbals.
(11) I know that would be an obvious thing to do to promote it, but the thought of strapping a guitar on again and playing all those songs from the past really does fill me with cold dread."
(12) Photograph: Hulton Archive Precisely how Shields achieves his queasy, waking-state guitar sound has long been the subject of stubbly examination.
(13) By 1973, I'd made it to London and I travelled around the UK with just my guitar and the clothes on my back.
(14) Online, you can find a blog by an advertising executive who worked with HMV for 25 years, in which he claims the company's former MD remarked in 2002 that "downloadable music is just a fad", which if it's true may well be music retail's own equivalent of "groups with guitars are on their way out, Mr Epstein".
(15) To the sound of an acoustic guitar and an earnest vocal, it opens with footage of a lonely Ed Miliband, wandering the dark, deserted streets of Westminster.
(16) She took a degree, wrote poetry, had Lord Longford running around for her and guitar lessons.
(17) His live shows begin with a skit mocking the pipsqueak talents of Jimi Hendrix: what price expanding the vocabulary of the rock guitar in a way unseen before or since when compared to a man from Penarth singing Yakety Yak?
(18) It was McKay who decided to bring guitar music to the dance kids in Ibiza.
(19) Chris – lassoed from a parallel universe where Tom Cruise gave Hollywood a swerve to focus on taking his guitar-alt-musings to open mic spots instead – looks on, coldly dissecting technique and cutting to seduction tips.
(20) Asked to define exactly what a music producer did, Ronson gave an example: "Working with someone like Amy Winehouse , she would come to me with just a song on an acoustic guitar and then you'd kind of dream up the rhythm arrangements and the track around it, all sorts of things.