(1) A search for other mutations in N-RAS exon-1 in T-ALL revealed a codon 13 mutation substituting aspartic acid (GAT) for glycine (GGT) in one of 18 patients.
(2) Thus, these data physically verify the serological characteristics of GAT-TsF1 that were originally defined solely on the basis of biological activity.
(3) We found that the cell-associated form of a factor specific for L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT-TsF1) is a 66 kDa protein which exhibits a slightly acidic isoelectric point, but no carbohydrate as determined by enzymatic analysis and lectin-affinity chromatography.
(4) Thus, helper T cells can serve as the cellular target of antigen-specific, MHC-restricted GAT-TsF2, and cloned helper T cells can be used as a homogeneous target population for analysis of the molecular mechanisms of T cell suppression.
(5) The maternal defect was shown to be a frameshift mutation with the deletion of a single T in the aspartic acid codon at position 690 (GAT), 11 amino acids N-terminal to the beginning of the transmembrane domain.
(6) The small inequality tau re gat greater than tau off2 suggests that charges which have returned from immobilization are not immediately available for displacement.
(7) Simultaneous immunization in vivo with the various GAT-Mphi or GAT-MBSA plus soluble GAT modulated the response pattern of these F(1) spleen cells such that they developed secondary responses only to F(1) and parental responder GAT-Mphi regardless of the response pattern observed after immunization with the various GAT-Mphi or GAT-MBSA alone.
(8) Two clonal cell lines, Cl-3 and Cl-7, were cloned from the PC-1 cell line, and these cell lines also carried the GAT point mutation at codon 12.
(9) Body weight was affected by Ea-B, Ir-GAT, and the interaction between Ea-B and Ir-GAT, but not by interaction with RSV response.
(10) The Charity Commission, which has already opened a case against the GAT, has been told of footage obtained by ITV’s Exposure: Charities Behaving Badly documentary.
(11) These results showed that immunization of (responder X responder)F1 mice with parental GAT-M phi results in the development of antigen-specific helper and suppressor T cells.
(12) The Plowell allele was shown in one M3P heterozygous individual to be due to a GAT(Asp) to GTT(Val) change at codon 256, in agreement with a previous study based on hybridization with allele-specific oligonucleotides.
(13) T cell subsets from virgin and immunized mice, which are Ir gene controlled nonresponders to GAT, which regulate antibody responses to GAT have been characterized.
(14) When cultured in the presence of exogenous rIL-2 as a growth factor, GAT-specific Th cell lines secreted mainly IL-4, whereas bacillus Calmette Guérin-specific lines produced predominantly IL-2.
(15) Addition of GAT to cultures of spleen cells from nonresponder mice also prevents development of the GAT-specific PFC responses stimulated by GAT-MBSA.
(16) Anti-idiotypic antisera made against each of the 15 hybridoma anti-GAT antibodies preferentially bound homologous ligand and showed minimal binding activity to specifically purified serum anti-GAT antibodies.
(17) The inequality tau re gat greater than tau re Na was larger and statistically significant at -100 and -110 mV.
(18) Haplotypes with high antibody responses to GAT had significantly higher antibody titers to PM and MG vaccines than haplotypes with low antibody responses.
(19) In contrast, the Th cell line 52.3 used as control could be induced to express high levels of IL2R only after exposure to GAT; nevertheless, IL2 seems to play a critical role in the in vitro survival of the resting state of 52.3 T cells.
(20) These results suggest that posttranslational modification, including glycosylation, is not required for biological activity or for expression of the I-J epitope on the GAT-TsF2 molecule.
Nat
Definition:
(adv.) Not.
() Not at; nor at.
Example Sentences:
(1) Only NAT activity exhibited daily changes, rising at the onset of darkness and resuming low values shortly before the end of the scotophase.
(2) Most of the money, says WDM, was used to buy shares in Bumi , the troubled London-listed firm co-founded by financier Nat Rothschild that owns large stakes in some of the biggest mining projects in East Kalimantan.
(3) This arylamine NAT acetylates p-aminobenzoic acid thereby demonstrating a monomorphic pattern of acetylation.
(4) In addition, the two enantiomers of D600 also inhibit NAT induction, the D-form slightly more effectively than the L-form.
(5) The ratio of paraoxon insensitive AHAT to OAT to NAT of PABA to NAT of 2-AF appears to be 1:2:11:22 using freshly made cytosols from frozen livers.
(6) The substrate specificity of NAT correlated well with the substrate range of the acetyltransferase in S. noursei and Tn1825-determined streptothricin resistance in Gram-negative bacteria.
(7) Incubation conditions that activate cyclic AMP-dependent protein kinase in retinal homogenates had no effect on NAT activity, suggesting that direct phosphorylation of NAT was probably not involved in the response to elevating cyclic AMP in situ.
(8) It was an accident when the Nats won an overall majority in the 2011 teeth of recession.
(9) Increasingly, you can discern a more minor-key debate among some Nats.
(10) NAT activity was detectable in the cultures under all conditions studied, and was markedly increased by drugs that increase intracellular cyclic AMP levels and cyclic AMP-dependent protein kinase activity: 8-bromocyclic AMP, forskolin, and 3-isobutyl-1-methylxanthine (IBMX).
(11) In contrast, levels of isoniazid N-acetyltransferase and N-hydroxy-3,2'-dimethyl-4-aminobiphenyl O-acetyltransferase activities in mouse liver cytosol appeared to be independent of the arylamine Nat acetylator gene.
(12) There was a decision to preference a new entrant into the WA political field, an Australian Aboriginal, who happens to be a member of the National Party, and to symbolically, I suppose, display him in the preference list … Where possible, where we see shining stars in individual parties, like Scott, or this guy from the Nats, we should individually preference them higher.
(13) NAT activity was significantly depressed on experimental days 1, 3 and 5, and slightly depressed on day 7.
(14) One part was used to estimate serotonin N-acetyltransferase (NAT) activity.
(15) The activity of 3 enzymes related to the bioactivation of toxic compounds and the development of cancer--cytochrome P450 IA2, N-acetyl transferase (NAT), and xanthine oxidase (XO)--can be measured from the ratios of formed metabolites excreted into urine.
(16) The activity of total MAO was about 10 times greater than that of NAT.
(17) Noradrenergic inhibition of 3-isobutyl-1-methylxanthine-augmented cAMP levels and NAT activity was reversed by yohimbine (an alpha 2-adrenergic antagonist) but not by prazosin (an alpha 1-adrenergic antagonist).
(18) A genetic polymorphism of human liver arylamine N-acetyltransferase (NAT; EC 2.3.1.5) enzyme activity divides populations into distinguishable "slow acetylator" and "rapid acetylator" phenotypes.
(19) After an 8-h advance of the LD cycle by shortening of one dark period, the NAT rhythm adjusted to the advance shift within 5 cycles only; during the first 2-3 cycles the rhythm was abolished.
(20) 41 patients with different AV stages were studied with the quantitative NAT test.