(1) CCB-LI was produced in large amounts in SCLC cell lines as compared to PST- and GAWK-LIs.
(2) This peptide, denoted GAWK, could originate from chromogranin B following specific cleavage at the basic amino acids flanking both termini of GAWK.
(3) The complete sequence of this 74 amino acid polypeptide, called GAWK, has been determined.
(4) A quiet word, a hushed farewell and a bowing out – without the Commonwealth gawking.
(5) Production of chromogranin (Cg)A and B derived peptides [pancreastatin (PST), GAWK, CCB] was studied using human lung carcinoma derived cell lines.
(6) GAWK (chromogranin-B 420-493) is a 74 amino acid peptide recently isolated from human pituitaries.
(7) Endocrine cells containing GAWK-like immunoreactivity were found also to be immunoreactive for chromogranin B.
(8) In a manner reminiscent of the relationship between pancreastatin and chromogranin A, it is proposed that both GAWK and CCB are produced from chromogranin B after specific processing at basic amino acids.
(9) Using two different antibodies (directed against GAWK [1-17] and [20-38] fragments) GAWK-LI was measured in tumors from 194 patients and in the plasma of 434 patients by RIA.
(10) PST, GAWK and CCB-LIs, secreted by these cell lines, consisted of several peaks, and these peaks were different among cell lines.
(11) We must “stop China’s cyber attacks, stop their territorial expansion into international waters,” stop Russia from “[encountering] mush” and “pushing” with bayonets, make sure Israel isn’t having a sad, cripple Iran with sanctions and ignore everything about climate change because “the greatest threat to future generations is radical Islamic terrorism and we need to do something about it.” The great thing about ignoring science and practicality while threatening to go to war against more than 1.5bn people around the globe is that, if there are any enemy survivors after the bombing stops, they can sail to the port city of Orlando and gawk enviously at all the free people queuing up for their mandatory drug tests atop a natural gas pipeline But don’t sell Walker short on his zero foreign policy experience.
(12) Plasma concentrations of GAWK-LI were found to be elevated in patients with endocrine tumor, but more so in those with pancreatic tumors than with pheochromocytomas.
(13) GAWK is a recently discovered peptide isolated from extracts of human pituitary gland and subsequently shown to be identical to sequence 420-493 of human chromogranin B.
(14) Our results show that 7B2 and the two fragments of secretogranin 1 (GAWK and CCB) are the best biochemical markers of neuro-endocrine differentiation in human lung tumours.
(15) High concentrations of GAWK-LI were also found in other types of endocrine tumors including carcinoid, medullary carcinoma of thyroid, pancreatic, and ACTH-producing lung tumors.
(16) So the powerful, by definition, deserve to be gawked at.
(17) A previously reported CgB-derived pituitary peptide, GAWK, was further processed at a conserved internal dibasic site to yield fragment 6, indicating alternative processing in different tissues.
(18) "You'd want to be one heck of a man to do it though, as there is huge windows at the front of the shop so passer-bys can gawk in and shame the menly-men knitting 'til their hearts content."
(19) Anyone old enough to have gawked at Diana’s progress, from uneducated 19-year-old target of a secretive thirtysomething, into a wildly competitive, ungovernable celebrity, will surely agree that her achievements merit something more personal, especially considering the steadily declining quality of royal entertainment.
(20) He took up a position at the front of the crowd, which gawked at him.