(1) A statistically significant difference in seizure frequency from the baseline to the treatment phase was noted between patients receiving placebo and GBP 1,200 mg, in whom seizure frequency decreased 57%.
(2) The synthesis of GBP is inducible by IFNs in all human diploid fibroblast cell lines that we studied.
(3) A growth-blocking peptide (GBP) with repressive activity against juvenile hormone (JH) esterase has been isolated from the last (6th) instar larval plasma of the armyworm Pseudaletia separata (Lepidoptera: Noctuidae) parasitized by the parasitoid wasp Apanteles kariyai (Hymenoptera: Braconidae) (1,2).
(4) We describe several differences between the signal transduction events that result in transcriptional activation of the human gene coding for a guanylate-binding protein (GBP) by alpha interferon (IFN-alpha) and gamma interferon (IFN-gamma).
(5) Immunocytochemistry and Western blots using monoclonal antibodies to the GBP demonstrated an increase in GBP-positive neurons and their staining intensity with time in culture.
(6) In this report, it is shown that the IFN-alpha stimulated genes (ISGs) 15, 54, 56, and GBP are transcriptionally induced by dsRNA.
(7) Ten percent GBP was effective in lowering glycemic excursions after sucrose and starch challenges.
(8) The 87-kDa GBP has no glucosyltransferase activity.
(9) RO #GBP November 6, 2013 Shaun Richards (@notayesmansecon) Good news!
(10) This component was recognized by anti-human glucocorticoid receptor antibodies but not by nonimmune serum, indicating that the 92K component was the reduced denatured GBP.
(11) IFN-gamma led to the formation of a stable intracellular signal which led to continued GBP transcription even if the ligand was withdrawn, whereas IFN-alpha-induced GBP transcription decayed rapidly if IFN-alpha was withdrawn.
(12) Among the patients studied, we found a higher level GBP accumulation (2.3x) in patients treated with IFN-beta than in those treated with IFN-gamma (1.6x).
(13) This photolabeling reaction can be inhibited only by guanylates but cannot be inhibited by other nucleotides, suggesting a specific association of GBP to guanylates.
(14) A clear relationship was seen in all dogs so that an increase in GBP inhibited SO activity.
(15) Inducible binding proteins for C4-dicarboxylic acids (DBP) and glucose (GBP) were isolated from Pseudomonas aeruginosa by extraction of exponential-phase cells with 0.2 M MgC12 (pH 8.5) and by an osmotic shock procedure without affecting cell viability.
(16) Immunoblot studies of synaptic membranes isolated from rat brain using antibodies raised against a previously purified glutamate-binding protein (GBP) indicated labeling of an approximately 70-kDa protein band.
(17) The binding of radioactive glucose by GBP was significantly inhibited by 10-fold concentrations of glucose, galactose, and glucose-1-phosphate but not by the other carbohydrates tested.
(18) Immunopurified, [3H]DM-labeled GBP subjected to NEPHGE reached isoelectric equilibrium after 6 h of electrophoresis at 400 V. A single, broad peak of radioactivity was identified at pH approximately equal to 6.3.
(19) Second-dimension analysis of the NEPHGE-separated GBP by SDS-PAGE resolved this peak into two discrete, 92K, isoforms of apparent pI = 5.7 and 6.0-6.5.
(20) Adolescent rats fed guar gum or GBP diets gained less weight than the cellulose group; only the guar gum group displayed improved carbohydrate tolerance.
Pound
Definition:
(v. t.) To strike repeatedly with some heavy instrument; to beat.
(v. t.) To comminute and pulverize by beating; to bruise or break into fine particles with a pestle or other heavy instrument; as, to pound spice or salt.
(v. i.) To strike heavy blows; to beat.
(v. i.) To make a jarring noise, as in running; as, the engine pounds.
(n.) An inclosure, maintained by public authority, in which cattle or other animals are confined when taken in trespassing, or when going at large in violation of law; a pinfold.
(n.) A level stretch in a canal between locks.
(n.) A kind of net, having a large inclosure with a narrow entrance into which fish are directed by wings spreading outward.
(v. t.) To confine in, or as in, a pound; to impound.
(pl. ) of Pound
(n.) A certain specified weight; especially, a legal standard consisting of an established number of ounces.
(n.) A British denomination of money of account, equivalent to twenty shillings sterling, and equal in value to about $4.86. There is no coin known by this name, but the gold sovereign is of the same value.
Example Sentences:
(1) Stringer, a Vietnam war veteran who was knighted in 1999, is already inside the corporation, if only for a few months, after he was appointed as one of its non-executive directors to toughen up the BBC's governance following a string of scandals, from the Jimmy Savile abuse to multimillion-pound executive payoffs.
(2) Any MP who claims this is not statutory regulation is a liar, and should be forced to retract and apologise, or face a million pound fine.
(3) It would cost their own businesses hundreds of millions of pounds in transaction costs, it would blow a massive hole in their balance of payments, it would leave them having to pick up the entirety of UK debt.
(4) "It will mean root-and-branch change for our banks if we are to deliver real change for Britain, if we are to rebuild our economy so it works for working people, and if we are to restore trust in a sector of our economy worth billions of pounds and hundreds of thousands of jobs to our country."
(5) The cull in 2013 required a policing effort costing millions of pounds and pulling in officers from many different forces.
(6) Each malnourished child was given 1 pound of dried skimmed milk (DSM) per week.
(7) The pound was also down more than 1% against the US dollar to $1.2835, not far off a 31-year low hit in the wake of June’s shock referendum result.
(8) I paid 200,000 Syrian pounds (£695) to leave Syria.
(9) "A pound spent in Croydon is of far more value to the country than a pound spent in Strathclyde," Johnson told the Huffington Post in an extraordinary interview this weekend.
(10) We continue to offer customers a great range of beer, lager and cider.” Heineken’s bid to raise prices for its products in supermarkets comes just a few months after it put 6p on a pint in pubs , a decision it blamed on the weak pound.
(11) Sir Ken Morrison, supermarkets Jersey trusts protect the billion-pound wealth of the 83-year-old Bradford-born Morrisons supermarket founder and a large number of his family members.
(12) "If we are going to turn our economy around, protect our NHS and build a stronger country, we will have to be laser-focused on how we spend every pound," he will say.
(13) From Tuesday, the Neckarsulm-based grocer will be the official supplier of water, fish, fruit and vegetables for Roy Hodgson’s boys under a multimillion-pound three-year deal with the Football Association.
(14) Hunt’s comments were, in many senses, a restatement of traditional, economically liberal ideas on relationships between doing wage work and poverty relief, mirroring, for example, arguments of the 1834 poor law commissioners, which suggested wage supplements diminished the skills, honesty and diligence of the labourer, and the more recent claim of Iain Duncan Smith’s Centre for Social Justice that the earned pound was “superior” to that received in benefits.
(15) Detailed analysis of the resources used revealed that the mean cost to the NHS of each case of NSAP was 807 pounds, the bulk of which was attributable to the hospital stay.
(16) Current obstetric recommendations call for 22-27 pound weight gain.
(17) She also complained of occasional night sweats, a 6-pound weight loss, vaginal discharge, and a low-grade fever for 6 weeks prior to admission.
(18) Correcting all this would cost hundreds of millions of pounds, a sum which councils and other housing providers simply cannot afford, they say.
(19) A total weight gain of 22 to 26 pounds is recommended, with the pattern of weight gain being more important than the total amount.
(20) Labour is exploring radical plans to give local councils and new regional bodies a central role in shaping the way billions of pounds of welfare funding is spent in order to bring down the benefits bill.