(a.) Relating to a genus or kind; pertaining to a whole class or order; as, a general law of animal or vegetable economy.
(a.) Comprehending many species or individuals; not special or particular; including all particulars; as, a general inference or conclusion.
(a.) Not restrained or limited to a precise import; not specific; vague; indefinite; lax in signification; as, a loose and general expression.
(a.) Common to many, or the greatest number; widely spread; prevalent; extensive, though not universal; as, a general opinion; a general custom.
(a.) Having a relation to all; common to the whole; as, Adam, our general sire.
(a.) As a whole; in gross; for the most part.
(a.) Usual; common, on most occasions; as, his general habit or method.
(a.) The whole; the total; that which comprehends or relates to all, or the chief part; -- opposed to particular.
(a.) One of the chief military officers of a government or country; the commander of an army, of a body of men not less than a brigade. In European armies, the highest military rank next below field marshal.
(a.) The roll of the drum which calls the troops together; as, to beat the general.
(a.) The chief of an order of monks, or of all the houses or congregations under the same rule.
(a.) The public; the people; the vulgar.
Example Sentences:
(1) The generally accepted hypothesis is a coronary spasm but a direct cardiotoxicity of 5-FU cannot be.
(2) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(3) No differences between the two substances were observed with respect to side effects and general tolerability.
(4) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(5) The Cole-Moore effect, which was found here only under a specific set of conditions, thus may be a special case rather than the general property of the membrane.
(6) Neuroleptics (chlorpromazine, reserpine and haloperidol) had not such an influence, though they somewhat increased the general activity of the animals.
(7) Even though attempts to generalize the data from childbearing women to women of childbearing age have an inherent conservative bias, the results of our study suggest that 988 women (95% CI 713 to 1336) aged 15 to 44 years in Quebec had HIV infection in 1989.
(8) A subsample of patients scoring over the recommended threshold (five or above) on the general health questionnaire were interviewed by the psychiatrist to compare the case detection of the general practitioner, an independent psychiatric assessment and the 28-item general health questionnaire at two different cut-off scores.
(9) Size analysis of the solubilized IgA IP employing sucrose density gradient ultracentrifugation, indicated that these were heterogeneous, with a size generally larger than 19 S.
(10) In general, the concentrations measured by bioassay were higher than those by HPLC.
(11) Issues such as healthcare and the NHS, food banks, energy and the general cost of living were conspicuous by their absence.
(12) These findings suggest that clonidine transdermal disks lower blood pressure in hypertensive patients, but produce local skin lesions and general side effects.
(13) Augmentation of transformation response was generally not seen at 40 degrees C; incubation at that temperature was associated with decreased cellular viability.
(14) When compared with self-reported exposures, the sensitivity of both job-exposure matrices was low (on average, below 0.51), while the specificity was generally high (on average, above 0.90).
(15) 2009 Visits the US for first time to address the UN general assembly.
(16) UN internal investigators delivered a report to the then secretary general, Kofi Annan, but it was not published.
(17) Those without sperm, or with cloudy fluid, will require vasoepididymostomy under general or epidural anesthesia, which takes 4-6 hr.
(18) Ferrocene derivatives, in general, show a degree of versatility, coupling the electron-transfer reactions of many enzymes.
(19) Increased iron levels in basal ganglia were generally associated with normal or elevated levels of ferritin immunoreactivity, for example, the substantia nigra in PSP and possibly MSA, and in putamen in MSA.
(20) Other recommendations for immediate action included a review of the Nursing and Midwifery Council and the General Medical Council for doctors, with possible changes to their structures; the possible transfer of powers to launch criminal prosecutions for care scandals from the Health and Safety Executive to the Care Quality Council; and a new inspection regime, which would focus more closely on how clean, safe and caring hospitals were.
Urethane
Definition:
(n.) A white crystalline substance, NH2.CO.OC2H5, produced by the action of ammonia on ethyl carbonate. It is used somewhat in medicine as a hypnotic. By extension, any one of the series of related substances of which urethane proper is the type.
Example Sentences:
(1) In urethane-anesthetized rabbits, IOP and blood pressure were lowered by intravenous administration of delta 9-THC but not by bolus cerebral administration.
(2) Chloralose-urethane is considered a suitable anaesthetic in rats when studying the effects of noradrenaline and guanethidine.
(3) Experiments were carried out under urethane anaesthesia.
(4) Urethane also produced a trend towards metabolic acidosis.
(5) Differential pulse voltammetry used in combination with an electrochemically treated carbon fiber electrode allowed the detection of 5-hydroxyindoles (5-HI) in the dorsal horn of the urethane-anesthetized rat.
(6) Seven or 14 days of treatment with the beta 2-adrenoceptor agonist clenbuterol, 0.3 mg kg-1, s.c., twice daily, increased the basal mean blood pressure in normotensive urethane-anaesthetized rats.
(7) To try to compare receptor compartment kinetics, receptor binding, and binding-response coupling for two smooth muscle types in vivo, pressor and uterine responses to oxypressin, an equipotent analog of oxytocin and vasopressin, were studied simultaneously in urethane-anesthetized, pentolinium-indomethacin treated rats.
(8) Single unit discharges in the ventromedial hypothalamic nucleus (VMH) and lateral hypothalamic area (LH) were extracellularly recorded in urethane anesthetised female rats, while various solutions were perfused through the stomach or duodenum via implanted polythene tubes.
(9) The role of the sympatho-adrenal system in the production of tachycardia accompanying the hypotensive response to hydralazine was studied in urethane-anesthetized rats subjected to previous bilateral adrenal demedullation or to pretreatment with 6-hydroxydopamine and compared with intact control animals.
(10) A germ line mutation causing a tumour ('tumour mutation') is weakly carcinogenic by itself, but it is strongly expressed in the progeny after postnatal treatment with a small dose of the carcinogenesis promoting agent urethane.
(11) Experiments were carried out on 36 urethane-chloralose aneasthesized, paralyzed, vagotomized and artificially ventilated rabbits.
(12) Fasting hyperglycemia was observed in urethane-anesthetized rats.
(13) Much evidence now exists which defines the ability of poly(ether)urethanes to selectively extract ions, especially calcium ion from solution.
(14) Filling of the gastric lumen of rats with 1.0 M NaCl solution (5 ml) for 10 min under urethane anesthesia caused an increase in the gastric fluid concentrations of prostaglandin (PG) E2, 13,14-dihydro-15-keto-PGE2 and 6-keto-PGF1 alpha as determined by radioimmunoassay.
(15) The effect of thyrotropin-releasing hormone (TRH) on the mechanism regulating growth hormone (GH) secretion was investigated in urethane-anesthetized male rats.
(16) In urethane-anesthetized rats, low frequency electrical stimulation of the thalamic radiation (TR) evoked an augmenting response in the somatosensory cortex (SCx) which was followed by rhythmic slow waves.
(17) The frequencies of transformations of primary human and Chinese hamster fibroblasts have been compared with the spontaneous and induced frequencies of mutation for resistance to thioguanine and ouabain, and for ability to use fructose, using the carcinogens benzo (alpha) pyrene and urethane.
(18) In urethane-anaesthetized rats clonidine was administered intravenously (i.v.
(19) One end of the spacer group was coupled to the derivatized surface through a urethane bond between the amine group of the spacer and the derivatized surface.
(20) These compounds were tested for anticarcinogenic activity against urethane-induced pulmonary adenomas and for antitumoral activity against some transplanted tumours such as leukemia L 1210, mammary adenocarcinoma Ca 755 and Walker carcinosarcoma 256.