(adv.) In general; commonly; extensively, though not universally; most frequently.
(adv.) In a general way, or in general relation; in the main; upon the whole; comprehensively.
(adv.) Collectively; as a whole; without omissions.
Example Sentences:
(1) The generally accepted hypothesis is a coronary spasm but a direct cardiotoxicity of 5-FU cannot be.
(2) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(3) No differences between the two substances were observed with respect to side effects and general tolerability.
(4) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(5) The Cole-Moore effect, which was found here only under a specific set of conditions, thus may be a special case rather than the general property of the membrane.
(6) Neuroleptics (chlorpromazine, reserpine and haloperidol) had not such an influence, though they somewhat increased the general activity of the animals.
(7) Even though attempts to generalize the data from childbearing women to women of childbearing age have an inherent conservative bias, the results of our study suggest that 988 women (95% CI 713 to 1336) aged 15 to 44 years in Quebec had HIV infection in 1989.
(8) A subsample of patients scoring over the recommended threshold (five or above) on the general health questionnaire were interviewed by the psychiatrist to compare the case detection of the general practitioner, an independent psychiatric assessment and the 28-item general health questionnaire at two different cut-off scores.
(9) Size analysis of the solubilized IgA IP employing sucrose density gradient ultracentrifugation, indicated that these were heterogeneous, with a size generally larger than 19 S.
(10) In general, the concentrations measured by bioassay were higher than those by HPLC.
(11) Issues such as healthcare and the NHS, food banks, energy and the general cost of living were conspicuous by their absence.
(12) These findings suggest that clonidine transdermal disks lower blood pressure in hypertensive patients, but produce local skin lesions and general side effects.
(13) Augmentation of transformation response was generally not seen at 40 degrees C; incubation at that temperature was associated with decreased cellular viability.
(14) When compared with self-reported exposures, the sensitivity of both job-exposure matrices was low (on average, below 0.51), while the specificity was generally high (on average, above 0.90).
(15) 2009 Visits the US for first time to address the UN general assembly.
(16) UN internal investigators delivered a report to the then secretary general, Kofi Annan, but it was not published.
(17) Those without sperm, or with cloudy fluid, will require vasoepididymostomy under general or epidural anesthesia, which takes 4-6 hr.
(18) Ferrocene derivatives, in general, show a degree of versatility, coupling the electron-transfer reactions of many enzymes.
(19) Increased iron levels in basal ganglia were generally associated with normal or elevated levels of ferritin immunoreactivity, for example, the substantia nigra in PSP and possibly MSA, and in putamen in MSA.
(20) Other recommendations for immediate action included a review of the Nursing and Midwifery Council and the General Medical Council for doctors, with possible changes to their structures; the possible transfer of powers to launch criminal prosecutions for care scandals from the Health and Safety Executive to the Care Quality Council; and a new inspection regime, which would focus more closely on how clean, safe and caring hospitals were.
Substantially
Definition:
(adv.) In a substantial manner; in substance; essentially.
Example Sentences:
(1) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
(2) 10D1 mAb induced a substantial proliferation of peripheral blood T cells when cross-linked with goat anti-mouse Ig antibody.
(3) Estimates of potential for gastrointestinal side effects using the rat enteropooling assay and in vivo monkey effects indicate that diarrhea will be substantially reduced with retention of uterine stimulating potency.
(4) Previous studies in this laboratory with particulate Mn3O4 have shown that preweanling rats have substantially higher tissue Mn concentrations than similarly treated adults, indicating possible differences in uptake or elimination or both.
(5) A more substantial decrease was found in Aberdeen and the larger towns near to Aberdeen than in the smaller towns further from the city.
(6) In contrast, human breast milk contained substantially increased levels of immunoreactive PTHrP.
(7) It was found that there was a substantial increase in mortality rates in the area under the jets where there was large noise radiation.
(8) But the amount of time spent above SPA has differed substantially between men and women due to women both living longer, and reaching state pension age earlier.
(9) Although statistical analysis did not show dramatic changes in all these parameters, some individual extreme values were substantially altered.
(10) Cholestyramine resin was beneficial in reducing stool bulk but had no substantial effect on fat absorption.
(11) Accordingly, LPA proved an extremely stable characteristic which did not show any substantial variations in the course of five years.
(12) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(13) Mitogen-stimulated cells always contain substantially higher levels of LDL receptor messenger RNA than corresponding resting cells.
(14) Considerable glucose 6-phosphatase activity survived 240min of treatment with phospholipase C at 5 degrees C, but in the absence of substrate or at physiological glucose 6-phosphate concentrations the delipidated enzyme was completely inactivated within 10min at 37 degrees C. However, 80mM-glucose 6-phosphate stabilized it and phospholipid dispersions substantially restored thermal stability.
(15) Amine metabolites, 5-hydroxyindoleacetic acid (5HIAA), and homovanillic acid (HVA) were not substantially affected by sleep deprivation, although there was a significant interaction of clinical response and direction of 3-methoxy-4-hydroxyphenylglycol (MHPG) change.
(16) The department of dietetics at a large teaching hospital has substantially reduced its food and labor costs through use of computerized systems that ensure efficient inventory management, recipe standardization, ingredient control, quantity and quality control, and identification of productive man-hours and appropriate staffing levels.
(17) Substantial percentages of both physicians and medical students reported access to drugs, family histories of substance abuse, stress at work and home, emotional problems, and sensation seeking.
(18) For further education, this would be my priority: a substantial increase in funding and an end to tinkering with the form of qualifications and bland repetition of the “parity of esteem” trope.
(19) The family members of depressed patients with six or more groups of DSM-III symptoms of major depression exhibited substantially higher rates of mood disorders than the family members of depressed patients with fewer than six groups of symptoms and the family members of patients with nonaffective disorders.
(20) The results presented here substantiate the hypothesis that in S. cerevisiae trehalose supplies energy during dormancy of the spores and not during the germination process.