(n.) One who, or that which, generates, begets, causes, or produces.
(n.) An apparatus in which vapor or gas is formed from a liquid or solid by means of heat or chemical process, as a steam boiler, gas retort, or vessel for generating carbonic acid gas, etc.
(n.) The principal sound or sounds by which others are produced; the fundamental note or root of the common chord; -- called also generating tone.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(3) Structure assignment of the isomeric immonium ions 5 and 6, generated via FAB from N-isobutyl glycine and N-methyl valine, can be achieved by their collision induced dissociation characteristics.
(4) Richard Bull Woodbridge, Suffolk • Why does Britain need Chinese money to build a new atomic generator ( Letters , 20 October)?
(5) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(6) It was also found that lipocortin I and ONO-RS-082, but not neomycin, facilitated the generation of GIF-producing T cells.
(7) Reactive metabolites which suppress splenic humoral immune responses are thought to be generated within the spleen rather than in distant tissues.
(8) The results indicate that OA-bearing macrophages primed T cells and generated helper T cells, whereas the culture of normal lymphocytes with soluble OA in the absence of macrophages generated suppressor T cells.
(9) Discrimination errors were used to generate a matrix of interletter and interpattern similarities.
(10) The presently available data allow us to draw the following conclusions: 1) G proteins play a mediatory role in the transmission of the signal(s) generated upon receptor occupancy that leads to the observed cytoskeletal changes.
(11) The present study was designed to test the hypothesis that the decreased Epi response following ET was due to 1) depletion of adrenal Epi content such that adrenomedullary stimulation would not release Epi, 2) decreased Epi release with direct stimulation, i.e., desensitization of release, or 3) decreased afferent signals generated by ET itself.
(12) This result suggests that tryptophan-86 may be importantly involved in the generation of the product excited state during aequorin bioluminescence.
(13) Midtrimester abortion by the dilatation and evacuation (D&E) method has generated controversy among health care providers; many authorities insist that this procedure should be performed only by a small group of experts.
(14) The transmission of alcoholism and its effects are thereby lessened for future generations of children of alcoholics.
(15) Furthermore, high-density catalase-positive--but not catalase-negative--E. coli can survive and multiply in the presence of competitive, peroxide-generating streptococci.
(16) We are the generation who saw the war,, who ate bread received with ration cards.
(17) These results suggest that CD4+ protective T cells generated by immunization with vBCG are characterized by the ability to produce IFN-gamma after stimulation with specific Ag.
(18) The alpha-ketoglutarate generated is reduced with glutamate dehydrogenase and NADH.
(19) We investigated the possible contribution made by oropharyngeal microfloral fermentation of ingested carbohydrate to the generation of the early, transient exhaled breath hydrogen rise seen after carbohydrate ingestion.
(20) Extensive proliferation has been shown to accompany the de novo generation of LAK cytotoxicity.
Issue
Definition:
(n.) The act of passing or flowing out; a moving out from any inclosed place; egress; as, the issue of water from a pipe, of blood from a wound, of air from a bellows, of people from a house.
(n.) The act of sending out, or causing to go forth; delivery; issuance; as, the issue of an order from a commanding officer; the issue of money from a treasury.
(n.) That which passes, flows, or is sent out; the whole quantity sent forth or emitted at one time; as, an issue of bank notes; the daily issue of a newspaper.
(n.) Progeny; a child or children; offspring. In law, sometimes, in a general sense, all persons descended from a common ancestor; all lineal descendants.
(n.) Produce of the earth, or profits of land, tenements, or other property; as, A conveyed to B all his right for a term of years, with all the issues, rents, and profits.
(n.) A discharge of flux, as of blood.
(n.) An artificial ulcer, usually made in the fleshy part of the arm or leg, to produce the secretion and discharge of pus for the relief of some affected part.
(n.) The final outcome or result; upshot; conclusion; event; hence, contest; test; trial.
(n.) A point in debate or controversy on which the parties take affirmative and negative positions; a presentation of alternatives between which to choose or decide.
(n.) In pleading, a single material point of law or fact depending in the suit, which, being affirmed on the one side and denied on the other, is presented for determination. See General issue, under General, and Feigned issue, under Feigned.
(v. i.) To pass or flow out; to run out, as from any inclosed place.
(v. i.) To go out; to rush out; to sally forth; as, troops issued from the town, and attacked the besiegers.
(v. i.) To proceed, as from a source; as, water issues from springs; light issues from the sun.
(v. i.) To proceed, as progeny; to be derived; to be descended; to spring.
(v. i.) To extend; to pass or open; as, the path issues into the highway.
(v. i.) To be produced as an effect or result; to grow or accrue; to arise; to proceed; as, rents and profits issuing from land, tenements, or a capital stock.
(v. i.) To close; to end; to terminate; to turn out; as, we know not how the cause will issue.
(v. i.) In pleading, to come to a point in fact or law, on which the parties join issue.
(v. t.) To send out; to put into circulation; as, to issue notes from a bank.
(v. t.) To deliver for use; as, to issue provisions.
(v. t.) To send out officially; to deliver by authority; as, to issue an order; to issue a writ.
Example Sentences:
(1) You lot have got real issues to talk about and deal with.
(2) The issue of the Schizophrenia Bulletin is devoted to articles representing this full range of conceptual and empirical work on first-episode psychosis.
(3) I’m not in charge of it but he’s stood up and presented that, and when Jenny, you know, criticised it, or raised some issues about grandparent carers – 3,700 of them he calculated – he said “Let’s sit down”.
(4) Issues such as healthcare and the NHS, food banks, energy and the general cost of living were conspicuous by their absence.
(5) Before issuing the ruling, the judge Shaban El-Shamy read a lengthy series of remarks detailing what he described as a litany of ills committed by the Muslim Brotherhood, including “spreading chaos and seeking to bring down the Egyptian state”.
(6) Critics say he is unelectable as prime minister and will never be able to implement his plans, but he has nonetheless pulled attention back to an issue that many thought had gone away for good.
(7) Much of the current information concerning this issue is from short-term studies.
(8) It is entirely proper for serving judges to set out the arguments in high-profile cases to help public understanding of the legal issues, as long as it is done in an even-handed way.
(9) It has announced a four-stage programme of reforms that will tackle most of these stubborn and longstanding problems, including Cinderella issues such as how energy companies treat their small business customers.
(10) One man has died in storms sweeping across the UK that have brought 100-mile-an-hour winds and led to more than 50 flood warnings being issued with widespread disruption on the road and rail networks in much of southern England and Scotland.
(11) The issue has been raised by an accountant investigating the tax affairs of the duchy – an agricultural, commercial and residential landowner.
(12) They are just literally lying.” In August Microsoft severed its ties, saying Alec’s stance on climate change and several other issues “conflicted directly with Microsoft’s values”.
(13) One is that the issue of whether the World Cup should go ahead in Russia and Qatar still firmly remains on the table.
(14) The data indicate greater legitimacy and openness in discussing holocaust-related issues in the homes of ex-partisans than in the homes of ex-prisoners in concentration camps.
(15) That’s a criticism echoed by Democrats in the Senate, who issued a report earlier this month criticising Republicans for passing sweeping legislation in July to combat addiction , the Comprehensive Addiction and Recovery Act (Cara), but refusing to fund it.
(16) It can feel as though an official opinion has been issued.
(17) The first part of this survey which dealt with equipment for the anterior segment was published in a previous issue of this journal.
(18) Problem definition, the first step in policy development, includes identifying the issues, discussing and framing the issues, analyzing data and resources, and deciding on a problem definition.
(19) Heathrow, likewise, said Gatwick's new runway would not solve the issue of hub capacity.
(20) The deep green people who have an issue with the language of natural capital are actually making the same jump from value to commodification that they state that they don’t want ... They’ve equated one with the other,” he says.