(n.) A class of objects divided into several subordinate species; a class more extensive than a species; a precisely defined and exactly divided class; one of the five predicable conceptions, or sorts of terms.
(n.) An assemblage of species, having so many fundamental points of structure in common, that in the judgment of competent scientists, they may receive a common substantive name. A genus is not necessarily the lowest definable group of species, for it may often be divided into several subgenera. In proportion as its definition is exact, it is natural genus; if its definition can not be made clear, it is more or less an artificial genus.
Example Sentences:
(1) The genome characterization of the typing strains for all 13 species of the genus Staphylococcus, included into the Approval List of the Names of Bacterial (1980), is presented.
(2) The genus Streptomyces was dominant in the two studied localities.
(3) The compounds favored the development of bacteria of the genus Pseudomonas and inhibited the growth of all other gram-negative bacteria.
(4) Organisms of the genus Bacteroides represent the major group of obligate anaerobes involved in human infections.
(5) The 212 strains of this proposed subserovar examined to date display biochemical and serological properties typical of the species, are sensitive to the genus-specific bacteriophage, and cause keratoconjunctivitis in the Sereny test.
(6) The new species has been placed in a new genus and the name Tricornia muhezae proposed.
(7) Although differing somewhat in their responses to various biochemical and biophysical tests, all strains were assigned to the genus Flavobacterium.
(8) Ten TBT-resistant isolates from estuarine sediments and 19 from freshwater sediments were identified to the genus level.
(9) A new genus of actinomycetes, Excellospora Agre a. Guzeva gen. nov., is suggested on the basis of this study.
(10) A new genus of spirochaetes, Hollandina, is also described.
(11) The first group consisted of all strains belonging to L. interrogans and serovar andamana of L. biflexa; the second group consisted of the remaining 5 serovars of L. biflexa; the third group consisted of the genus Leptonema; and the fourth group consisted of only L. parva.
(12) The reservosomes of Trypanosoma spp., sub-genus Schizotrypanum, could be differentiated from the multivesicular bodies of other trypanosomatids, since they lack true vesicles.
(13) Statistical analysis of 251 phylogenetically informative nucleotide positions rejects the "volvocine lineage" hypothesis, which postulates a monophyletic evolutionary progression from unicellular organisms (such as Chlamydomonas), through colonial organisms (e.g., Gonium, Pandorina, Eudorina, and Pleodorina) demonstrating increasing size, cell number, and tendency toward cellular differentiation, to multicellular organisms having fully differentiated somatic and reproductive cells (in the genus Volvox).
(14) In all cases, the determinants of the killer trait are carried by obligate bacterial endosymbionts belonging to the genus Caedibacter.
(15) Lastly, the CVA indicated major differences across the genus to be located in the teeth and jaws, suggesting diet might be an important distinguishing feature in Colobus.
(16) Another pigment 7 was specifically present in the skin of genus Rhacophorus and was deduced to be a pteridine derivative composed of five molecules of pterin-6-carboxylic acid [1].
(17) Bacteria of the genus Thiobacillus can obtain energy from the chemolithotrophic oxidation of inorganic sulphur and its compounds (sulphide, thiosulphate and polythionates) and use this energy to support autotrophic growth on carbon dioxide.
(18) A platelet-aggregating activity was found in many snake venoms, predominantly those of the genus Bothrops, that is apparent only in the presence of the platelet-aggregating von Willebrand factor of plasma.
(19) Sporobolomyces yuccicola is the sixth species of the intermedius group, a group of atypical species of the genus Sporobolomyces equipped with Q-9.
(20) This reduction was confined to strict anaerobes, mainly the genus Eubacterium and Bifidobacterium.
Lobeline
Definition:
(n.) A poisonous narcotic alkaloid extracted from the leaves of Indian tobacco (Lobelia inflata) as a yellow oil, having a tobaccolike taste and odor.
Example Sentences:
(1) Additional experiments demonstrated that lobeline suppressed the conversion of exogenous progesterone to testosterone, but did not affect the conversion of exogenous 17 alpha-hydroxyprogesterone to testosterone.
(2) Bath superfusion of nicotine or the nicotinic stimulants dimethylphenylpiperazinium (DMPP), lobeline, cytisine, tetramethylammonium or suberyldicholine (up to 100 microM) had little or no effect on the extracellular N-wave amplitude, or the membrane potential, input resistance or excitability of olfactory neurones recorded intracellularly.
(3) Interestingly, in the presence of the ganglionic stimulants DMPP (n = 6 slices) or lobeline (n = 5 slices) (10-50 microM), the effects of carbachol or oxotremorine-M were antagonized in a weak competitive-type manner (pA2 values = 5.58 and 5.63 respectively, estimated from Schild plots, constrained to unity slope).
(4) Although ineffective as stimulators of steroidogenesis by themselves, the three nicotinic receptor-selective agonists lobeline, dimethylphenylpiperazinium iodide (DMPP), and phenyltrimethylammonium iodide (PTMA) inhibited FSH-induced progesterone and 20 alpha-hydroxypregn-4-en-3-one production in dose-dependent fashions.
(5) Based on the concentrations in brain and known affinities for high-affinity nicotine binding sites, in vivo tests should show cytisine to be slightly more potent than nicotine and lobeline to have nicotine effects in the doses used.
(6) Lobeline inhibition of hCG-stimulated testosterone production was accompanied by decreases in medium accumulation of 17 alpha-hydroxypregnenolone (75%), 17 alpha-hydroxyprogesterone (85%), dehydroepiandrosterone (50%), and androstenedione (61%); however, the medium content of pregnenolone and progesterone were unchanged.
(7) In addition we found that (-)nicotine, (+)nicotine, and lobeline, but not the nicotine metabolite (-)cotinine nor acetylcholine, were able to displace [3H]dizocilpine ([3H]MK 801) binding in well-washed membranes obtained from rat brain.
(8) The lobeline sulphate seems to produce both in SEEG and hippocampus a shift toward low frequencies and in amygdala a drift toward high frequencies.
(9) Previous work has suggested that cytisine and lobeline are of low potency in producing nicotine-like behavioural effects, despite having some nicotine-like peripheral effects and potently inhibiting the binding of tritiated nicotine to the brain of the rat.
(10) Lobeline failed to produce a nicotine-like discriminative effect, even at doses that greatly reduced overall rates of responding.
(11) One of the most potent antagonists to nicotine was alpha-lobeline.
(12) Bilateral lesions of the paramedian reticular area of medulla destroying the PRN, abolished or reversed the depressor response to electrical stimulation of myelinated fibres of the carotid sinus nerve (CSN), attenuated the depressor response to carotid sinus stretch and augmented the pressor response to chemoreceptor stimulation by lobeline.
(13) Repeated administration of DMPP did not cause a tachphylaxis, however, lobeline and nicotine did induce a tachphylaxis.
(14) The N-cholinomimetic -- lobeline potentiates the evoked response of the brain cortex, whereas the N-cholinolytic -- beta-ethylene-splasmolytin -- depresses it.
(15) The rank order of inhibitory potencies was lobeline greater than DMPP greater than PTMA with IC50 values of 2 X 10(-6) M, 3 X 10(-5) M, and 3 X 10(-4) M, respectively.
(16) The pKa of (-)-lobeline HCl at 25 degrees C is 8.6 (approx), indicating that (-)-lobeline is at least 90% in the protonated form at physiological pH (7.6).
(17) The clastogenicity of lobeline and possible interactions between lobeline and ethyl alcohol were investigated in a mutagen-sensitivity assay on cultures of human lymphoblastoid cell lines.
(18) The effects of ethylketazocine (EKC) administered intraperitoneally and the nicotinic ligands (-)- and (+)-nicotine, (-)-cytisine, (-)-lobeline, and (+)-2-methylpiperidine administered into the 4th ventricle on the latency of the thermally evoked withdrawal reflex of the decerebrate rat were investigated.
(19) Lobeline administration induced an hyperpnea due to both an increase in tidal volume and respiratory rate; this increase in ventilation lasted for about 90 s and was accompanied by a sharp rise in the respiratory peak airflows, especially the expiratory ones.
(20) To determine whether this effect is elicited by other nicotinic agonists found in tobacco, the effects of chronic infusion with nicotine on brain nicotinic receptors were compared with those after anabasine and lobeline.