(1) Of the two major forms of cytotactin (220 and 200 kDa), the larger form predominated during development of the mouse brain and also predominated in mixed neuron-glia cultures but not in pure glial cultures.
(2) Ependymal cells developed luminal fronds that projected into the ventricle and the subpial glia displayed a very subtle gliosis in the form of thin multi-laminated processes.
(3) We also observed that this proliferative response of retinal glia requires more than 6 h of continuous exposure to thrombin.
(4) In response to NE stimulation of glia, in particular astrocytes, cAMP or its metabolites may accumulate at high enough concentrations in the extracellular space in cerebral cortex to affect neuronal function, possibly via adenosine receptors.
(5) Polarization microscopic studies proved that Levafix Red Violet E-2BL is bound to well-oriented fibrous proteins in glia fibers.
(6) Early (i.e., at 2 to 3 DIV) changes in glial numbers may result from an inhibition of the proliferative rate of non-GFAP-containing glia or astrocyte precursors, or an enhanced rate of glial death.
(7) Neither neurons nor glia bound to cytotactin in this assay.
(8) They also suggest that both the migration of cortical neurons on glia and the refinement of the mapping between the peripheral whisker field and its cortical representation may depend upon the distribution of substrate adhesion molecules.
(9) We studied the developmental course of this induced microgyria under light microscopy by examining changes in neurons, glia, and macrophages following a focal freezing insult on the day of birth (postnatal day [P]0).
(10) Seventy-two hours after retinal separation, the same result is obtained in the photoreceptors, but labeling intensity is greatly increased in both the nuclei and cytoplasm of Müller's glia.
(11) The results support the hypothesis that GPDH expression in Bergmann glia cells depends upon their sustained interaction with Purkinje cells, most likely involving direct cell-cell contact.
(12) Later, the astroglial processes of regenerated glia limitans showed very infolded surfaces and numerous filaments inside of them.
(13) These studies suggest that certain perineuronal glia are transformed into reactive astrocytes in areas of ischemic neuronal necrosis, although current data are insufficient to determine if the transforming cells are astrocytes, light oligodendrocytes, or intermediate glia.
(14) Glia occupied 25% of the neuropil within 1 mm of the dorsal root-transplant interface, but only 6% of the neuropil 1-2 mm from the interface.
(15) In the presence of beta-alanine (10(-3) M), a substrate specific inhibitor of high-affinity GABA transport into glia, tritiated GABA was accumulated by a high-affinity uptake system into myenteric ganglia and a subpopulation of mucosal cells.
(16) It was of interest to determine whether this class of glia is essential to the normal cytoarchitectural development of the neural retina.
(17) Proliferation of glia cells and decrease of nerve cells were also noted.
(18) Diverse molecules rapidly traverse the periaxonal sheath and a fraction of them enters the axons from glia or the glia from axons.
(19) Both types of cells are closely associated with processes of radial ependymal glia cells, which perhaps orient their migratory pathways.
(20) In addition, during regeneration, optic nerve glia express large amounts of the 50 kDa cytoskeletal protein, which they ordinarily express at only minimal levels.
Glioma
Definition:
(n.) A tumor springing from the neuroglia or connective tissue of the brain, spinal cord, or other portions of the nervous system.
Example Sentences:
(1) Clinicians should be aware of this new and unusual association of a cerebral glioma and acquired immune deficiency syndrome.
(2) Gliomas of the pregeniculate anterior visual pathways comprise about 5% of all intracranial tumors that occur in the first decade of life.
(3) The mean mitotic index for the GFAP+ cells was 6% (range 2-12%) as compared to a mean mitotic index of 29% for the GMK-7 glioma cell line.
(4) During the last decade, clinical studies with immunotherapy in recurrent gliomas have been added to the therapeutic regimens.
(5) Furthermore, cytotoxic antibodies had a lytic effect on the autologous glioma cells only in the presence of rabbit complement.
(6) The predominant specific aberrations in gliomas were an over-representation of chromosome 7 (13 cases) and an under-representation of chromosome 10 (16 cases).
(7) We have examined the effect of seven glutamate analogues (five gliotoxic and two neurotoxic) on the growth and viability of four human glioma cell lines, one human medulloblastoma cell line, and one human sarcoma cell line.
(8) We examined the effect of lactic acid on cultured human glioma cell lines expressing glial fibrillary acidic protein (GFAP), vimentin and neuron-specific enolase (NSE).
(9) Cobalt chloride and heat shock, which are potent inducers of HO mRNA in rat liver and rat C6 glioma cells, respectively, have only a small effect on the level of HO mRNA in mouse hepatoma cells.
(10) Similar nucleotide profiles for release of the alpha subunits of forms of Gi were noted for membranes of both the neuroblastoma x glioma hybrid cell line NG108-15 and of human platelets.
(11) Long-term ethanol exposure is known to inhibit bradykinin-stimulated phosphoinositide hydrolysis in cultures of neuroblastoma x glioma 108-15 cells.
(12) Effect of dalargin, an opioid peptide (a synthetic analogue of Leu-enkephalin), on proliferation and intensity of DNA synthesis of C6 glioma cells was studied.
(13) Pleomorphic glioma cells but especially astrocytoma cells reacted positively also for the GFA protein.
(14) We present interim survival data for a group of 83 adult patients with recurrent malignant glioma treated by implanting stimulated autologous lymphocytes into the tumour bed following surgical debulking.
(15) We present the first reported cases of mixed oligodendrocytic-astrocytic gliomas to occur in two members of the same family, a father and a son.
(16) We have developed a model cell culture system, using NG108-15 neuroblastoma-glioma hybrid cells, to study cellular tolerance to ethanol.
(17) The pHi measurements in glioma monolayers were carried out after 2-6 days of continuous exposure to 0.1 mM amiloride at physiological levels of Na+ and HCO3- to simulate the conditions during growth inhibition.
(18) Rat gliomas of subcutaneously transplanted RGc-6 cells were irradiated with X-ray either alone, or combined with ACNU, and the cell-survival was assayed in vitro.
(19) Unlike other tumors, the original pineal calcification could be recognized in two-thirds of glioma cases and was displaced anteriorly and superiorly in most.
(20) Thirty-eight cases of optic gliomas seen at the University of California, San Francisco, were reviewed.