(n.) A little globe; a small particle of matter, of a spherical form.
(n.) A minute spherical or rounded structure; as blood, lymph, and pus corpuscles, minute fungi, spores, etc.
(n.) A little pill or pellet used by homeopathists.
Example Sentences:
(1) The values obtained are shown to be lower than those calculated for arigid pepsin globule.
(2) Histologically, foci strongly resembling hepatocellular carcinoma with hyaline globules were noted.
(3) A large portion of the N-terminal globule of human collagen VI was prepared from the culture medium of stably transfected human embryonic kidney cell clones.
(4) Ultrastructurally, the globules measured 0.5-1.5 mu in diameter and they were usually not membrane bound.
(5) Calcification initially occurs in maxtrix vesicles (or calcifying globules) which are very numerous between the collagen fibrils of the osteoid tissue, and successively spreads into the surrounding interfibrillar matrix.
(6) This early rejection was associated with local appearance of globule leucocytes and increased concentration of T. colubriformis-specific IgG1 and IgG2 in intestinal mucus.
(7) Eosinophilic globules were found in 17% of the 34 nevi, and congenital features in 8.8%.
(8) In some areas, the tumor shows a striking resemblance to Kaposi's sarcoma; criss-crossing fascicles of spindle cells are interspersed with narrow vascular spaces, but PAS-positive hyaline globules are absent.
(9) Kamino's eosinophilic globules could be considered another important sign for the differential diagnosis between pigmented spindle cell nevus and malignant melanoma.
(10) Deposits of reaction product were found in varying amounts on the membranes of primary vesicles in the globules.
(11) Double immunofluorescence microscopy revealed that hsp70 codistributed with the c-myc protein in distinct globules in the nucleus of many but not all myc-positive cells.
(12) Lipids associated with fat globule membrane components increased during the dry period.
(13) Examination of possibility of AAT deficiency should be performed in every case, where the cause of liver disease is unsolved; this examination is especially indicated by the presence of typical PAS positive, diastase-resistant, AAT immunreactive globules in hepatocytes.
(14) In addition to exposing the underlying filamentous substructure of the matrix, protease treatment also revealed large, straight fiber bundles and globules of amorphous material suspended in the filamentous web.
(15) Cow, goat, and human globules were subjected to varying concentrations of the bile salt taurodeoxycholate at 37 degrees C for 2 min, and the released material was obtained by centrifugation at 2 degrees C and 50,000 g for 1 h. Sedimented pellets were analyzed for phospholipid and protein and were characterized further by sodium dodecylsulfate-polyacrylamide gel electrophoresis.
(16) The examination of the data leads to the conclusion on the existence of two possible mechanisms: the variation of properties of surface tryptophan residues environment and paramagnetic orientation of protein globule under the influence of a magnetic field.
(17) Myxoglobulosis is a rare morphologic variant of appendiceal mucocele characterized by intraluminal mucinous globules of the appendix.
(18) A remarkable array of filaments, approximately 0.5 micron in length, was seen on human, but not bovine, globules.
(19) In 10 of 56 patients with primary liver carcinoma the nontumorous hepatocytes contained diastase resistant, periodic acid-Schiff positive and alpha-1-antitrypsin positive (immunoperoxidase technique) globules.
(20) The antigenic relationship between the milk fat globule membrane (MFGM) and the hydrophobic fraction of proteose-peptone (HFPP) was demonstrated, using a mono-specific anti-HFPP antibody.
Vacuole
Definition:
(n.) A small air cell, or globular space, in the interior of organic cells, either containing air, or a pellucid watery liquid, or some special chemical secretions of the cell protoplasm.
Example Sentences:
(1) Chloroquine induced large cytoplasmic vacuoles, whereas the other drugs (quinacrine, 4,4'-diethylaminoethoxyhexestrol, chlorphentermine, iprindole, 1-chloro-amitriptyline, clomipramine) caused formation of lamellated or crystalloid inclusions as usually seen in drug-induced lipidosis.
(2) Aberrant forms (elongated and twisted) in the vacuole and double virions in the plasma membrane were observed as early as 65 h after infection.
(3) Combined SEM and TEM examination of the endothelium of compressed segments revealed "craters" and "balloons", blebs and vacuoles, swollen mitochondria, dilated granular endoplasmic reticulum, and subendothelial edema.
(4) Electron microscopy revealed the presence of a hitherto unreported peculiar "pilovacuolar" inclusion in numerous mitochondria, composed of an electron dense pile or rod within a vacuole, while globular or crystalline inclusions were absent.
(5) The mode of action is as yet undetermined, but intracellular vacuoles may be the primary targets.
(6) Thin layers of carbon (20 microns) and vacuoles (30 microns) suggested a large temperature gradient along the tissue ablation front.
(7) It can be estimated that there were about 20 small vacuoles per erythrocyte.
(8) Phagosomes and dense bodies reminiscent of Russel bodies also occurred in the Mikulicz cells, in the vacuoles of which formations representing Klebsiella rhinoscleromatis were demonstrated.
(9) Thus, multiparae had very thick border zones composed predominantly of large nodules and, additionally, of vacuolated cells and fibrous tissue.
(10) Some of these vacuoles had remnants of mitochondrial cristae or were enlarged endoplasmic reticulum.
(11) Portal lipogranulomas show a distinctive morphology with fat vacuoles surrounded by macrophages.
(12) Under the electron microscope, slices appeared vacuolated near the cut surfaces, but well preserved internally (greater than 40 micron from the edge).
(13) By the time the bud was half the diameter of the mother cell, it almost always bore a vacuole.
(14) Large intracellular vacuoles, which arose from dilated cisternae of the rough-surfaced endoplasmic reticulum, were fused together, and marked swelling of the mitochondria was also noted.
(15) This exogenous protein tracer could be seen in apical vacuoles and phagosomes in the cuboidal parietal epithelium.
(16) are adherent to the cell membrane and are internalized into cytoplasmic vacuoles.
(17) This intermediate compartment contained only small amounts of cathepsin L in comparison to lysosomes and was bound by a double membrane, typical of nascent vacuoles.
(18) Large (about 2 micron in diameter), pale vacuoles, probably of extracellular character, were found mostly in the vicinity of the perivascular septum.
(19) Factors associated significantly with the degree of vacuolization were sex (females were affected more severely than males), body weight, relative liver weight, and the laboratory conducting the study.
(20) Histologic examination of one patient from each pedigree showed two characteristic findings in corneal epithelium; the previously designated "peculiar substance" in the cells, and the vacuolated homogeneous substance mostly within the cysts.