What's the difference between globulin and hemoglobin?

Globulin


Definition:

  • (n.) An albuminous body, insoluble in water, but soluble in dilute solutions of salt. It is present in the red blood corpuscles united with haematin to form haemoglobin. It is also found in the crystalline lens of the eye, and in blood serum, and is sometimes called crystallin. In the plural the word is applied to a group of proteid substances such as vitellin, myosin, fibrinogen, etc., all insoluble in water, but soluble in dilute salt solutions.

Example Sentences:

  • (1) We are currently conducting a trial to compare the ability of DHPG administered plus an anti-CMV immune globulin preparation with acyclovir to prevent posttransplant TI-CMV disease.
  • (2) No significant difference was found for triglycerides, uric acid, albumin and gamma-globulins.
  • (3) The antigens tested included bovine serum albumin, gamma-globulin, and ribonuclease.
  • (4) Differences regarding subfraction patterns of the gamma-globulin region seemed to be influenced of whether supra- or infratentorial structures were affected.
  • (5) Using a soluble ICAM-2 Ig fusion protein (receptor globulin, Rg) we demonstrate the costimulatory effect of ICAM-2 during the activation of CD4+ T cells.
  • (6) The first step is the preparation of a globulin-enriched fraction by precipitation with ammonium sulfate at 50% saturation, or of an immune-complex-enriched fraction by precipitation with 5% polyethylene glycol 6000.
  • (7) The relative amounts of stable bonds formed by TOD and human serum albumin and TOD and gamma-globulin varied inversely with the concentration of the proteins.
  • (8) The blood-brain barrier (BBB) was studied in 76 neonates of different gestation age in health and disease by means of detecting specific alpha-1-globulin in blood serum with the aid of ELISA.
  • (9) A 1977 College of American Pathologists survey of hospitals has been analyzed to compare Rh immune globulin usage (RhIgG) with methods used to screen and confirm fetomaternal hemorrhage (FMH).
  • (10) The rats which had received the anti-BSA globulin had significantly more antigen in renal cortex and in isolated glomeruli than the control group.
  • (11) Oligomenorrhea was frequently found but segregated separately from the thyroxine-binding globulin deficiency; of seven women with low levels, three had normal monthly menstrual cycles.
  • (12) This resulted in a false-positive recall incidence greater than 92% owing to various additional factors which also influence T4 levels: thyroxine-binding-globulin deficiency, prematurity, and maternal drug ingestion.
  • (13) On polyacrylamide gels at pH 8.9 in the absence of sodium dodecyl sulfate, the bone-resorptive protein migrates with the mobility of an alpha 2-globulin.
  • (14) We conclude that home self-administration of intravenous immune globulin is feasible, safe, and effective in selected patients.
  • (15) Since deglycosylation decreases the frictional ratio of thyroxine binding globulin, it is concluded that, although sialic acid and other sugar residues are in contact with the protein surface, the hydrated carbohydrate chains protrude partially into the solvent.
  • (16) The greater frequency of dysovulation in obese women, notably those who put on weight rapidly, is accompanied by numerous hormonal changes, including reduced sex hormone-binding globulin, increased ovarian and adrenal androgen production, increased peripheral aromatization of androgens to oestrogens, and altered gonadotropin pulsatile secretion.
  • (17) The plasma content of testosterone, dihydrotestosterone, sex hormone binding globulin, apparent free testosterone concentration, follicle-stimulating hormone, and luteinizing hormone were not significantly different between the groups.
  • (18) It was shown that indocyanin green (ICG) test, prothrombin time (PT), lecithin cholesterol acyltransferase (LCAT), gamma-globulin, age of patients and total bilirubin appeared to be important factors to discriminate the subjected patients into two groups.
  • (19) Fluorescein-labelled gamma globulin fractions of anti-avidin and anti-uteroglobin both bound to blastocysts, but pure FITC-IgG showed binding only of anti-uteroglobin.
  • (20) To assess the efficacy of the combination of the antiviral agent ganciclovir (9-1,3 dihydroxy-2-propoxymethylguanine) and high-dose intravenous immune globulin for treating cytomegalovirus interstitial pneumonitis after allogeneic bone marrow transplantation.

Hemoglobin


Definition:

  • (n.) The normal coloring matter of the red blood corpuscles of vertebrate animals. It is composed of hematin and globulin, and is also called haematoglobulin. In arterial blood, it is always combined with oxygen, and is then called oxyhemoglobin. It crystallizes under different forms from different animals, and when crystallized, is called haematocrystallin. See Blood crystal, under Blood.

Example Sentences:

  • (1) Participants (n=165) entering a week-long outpatient education program completed a protocol measuring self-care patterns, glycosylated hemoglobin levels, and emotional well-being.
  • (2) Thus, saponin and ammonium chloride can be used to isolate whole infected erythrocytes, depleted of hemoglobin, by selective disruption of uninfected cells.
  • (3) The resonance Raman spectra of oxy and deoxy cobalt-substituted hemoglobin (CoHb) are reported.
  • (4) Between whole blood and whole blood related to hematocrit and hemoglobin content, r was 0.8 and 0.89 respectively (p less than 0.001).
  • (5) Hemoglobin British Columbia was found in an East Indian living in Vancouver, British Columbia, Canada.
  • (6) The canine system allows quantitative separation of native heme containing alpha and beta chains which recombine to for tetrameric hemoglobin with normal functional properties (n = 2.17).
  • (7) TNBS reacts to an extremely small extend with hemoglobin over the concentration range 0.4 to 4 mM whereas FDNB reacts with hemoglobin to a very large extent (50 fold more than TNBS).
  • (8) Since iron from fortified formulas is well absorbed during the first three months of life, even if it is not immediately used for hemoglobin formation, an inccrease in the iron stores will occur...
  • (9) The present results using approximately 12% hemoglobin concentration in 0.1 M Bistris buffer at pD 7 and 27 degrees C with and without organic phosphate show that there is no significant line broadening on oxygenation (from 0 to 50% saturation) to affect the determination of the intensities or areas of these resonances.
  • (10) A significant association between G6PD deficiency and hemoglobin S correlated with previous studies on similar samples from the general population.
  • (11) Both eosin derivatives, however, inactivate acetylcholinesterase upon illumination of air-equilibrated samples of hemoglobin-free labeled ghosts.
  • (12) A fiberoptic flow-directed catheter inserted into the hepatic vein continuously measures hepatic venous oxygen hemoglobin saturation (ShvO2).
  • (13) These agents have been well-tolerated and generally produce a high incidence of sustained improvements in neutrophil counts and marrow morphology, although hemoglobin and platelet counts have generally not been altered.
  • (14) Hemoglobin A reductively ethylated at the alpha-amino groups eluted on CM-52 ahead of unmodified hemoglobin A, and hemoglobin A reductively ethylated at the epsilon-amino groups.
  • (15) Five of the children presented an "aplastic crisis," for example, a sudden decrease in hemoglobin concentration associated with absence of reticulocytes in the peripheral blood, and four were admitted with unremitting severe pain because of a "vaso-occlusive crisis."
  • (16) Plasma and red cell sorbitol concentrations, fasting plasma glucose, glycosylated hemoglobin (GHb) were evaluated in 30 diabetic patients and 42 normal subjects.
  • (17) A new type of artificial blood, pyridoxylated hemoglobin-polyoxyethylene conjugate (PHP) solution, (developed by PHP research group of the department of health and welfare of Japan, and produced by Ajinomoto Co., Inc. Tokyo) as an oxygen-carrying component, has been recently devised using hemoglobin obtained from hemolyzed human erythrocytes.
  • (18) Using the intersection point of these pH-logPCO2 lines as a point of equal hemoglobin-independent "base excess" for each condition, values for true base excess were plotted.
  • (19) Measurements of mechanical stability of Hb Santa Ana showed that the oxy-form of this hemoglobin was 10 times more unstable than that of Hb S and 100 times more unstable than that of Hb A.
  • (20) In addition, although aspirin does transfer the acetyl group to hemoglobin both in vitro and in vivo, in our experiments the reaction does not result in any alteration in the oxygen equilibrium of either intact erythrocytes or hemoglobin in solution.

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