(1) Further analysis with two other synthetic peptides (212Cys to 222Glu and Cys X 221Ile to 236Glu) indicated that the dodecapeptide Ile-Glu-Phe-Gln-Lys-Asn-Asn-Arg-Leu-Leu-Glu mimicked either the whole or a major part of the neutralization epitope.
(2) This indicated that proteolysis at Lys1313-Glu also proceeded in native alpha 2M.
(3) In contrast, strains carrying the substitutions Ile-30----Phe, Gly-33----Leu, Gly-58----Leu, and Lys-34----Val and the Lys-34----Val, Glu-37----Gln double substitution were found to possess a coupled phenotype similar to that of the wild type.
(4) The substructural units, 5-14 linear and 5-14 cyclic, have been used as models for MCH-- H-Asp1-Thr-Met-Arg-Cys-Met-Val-Gly-Arg HO-Val17-Glu-Trp-Cys-Pro-Arg-Tyr-Val in 1H-nmr conformational studies.
(5) However, when it has attained a length of about half the cell body diameter, it becomes SUP GLU+ and 6-11B-1+.
(6) The commercially available chromogenic p-nitroanilide substrates Pro-Phe-Arg-NH-Np (S2302 or chromozym PK), Glp-Pro-Arg-NH-Np (S2366), Ile-Glu-(piperidyl)-Gly-Arg-NH-Np (S2337), and Ile-Glu-Gly-Arg-NH-Np (S2222) were tested for their suitability as substrates in these assays.
(7) We then used synthetic peptides spanning the active fragment to identify the primary sequence of the adhesive site as Leu-Arg-Glu (LRE): neurons attach to an immobilized LRE-containing peptide, and soluble LRE blocks attachment of neurons to the s-laminin fragment.
(8) This established that the Gly----Glu substitution at amino acid 142 is sufficient to abolish enzymatic activity and to result in the chylomicronemia syndrome observed in these patients.
(9) Comparison of the human and mouse repeats revealed a highly conserved Glu-Asp core in each unit, implicating the functional significance of this motif.
(10) Hippocampal GLU content decreased during development, whereas GABA content was constant for all the ages investigated.
(11) Retrograde transport of horseradish peroxidase and immunocytochemical visualization of glutamate (Glu) were combined to investigate the neurotransmitter used by cortico-cortical neurons in the first (SI) and second (SII) somatic sensory areas of macaque monkeys.
(12) beta-GLU I, beta-GLU II and beta-GLU III, the number of which varies from one to three during the growth of the organism.
(13) Three of the four bonds cleaved in actin, two of the three in troponin C, and all of the bonds hydrolyzed in AAP and pro-IL-1 beta have a P2' Glu residue.
(14) The lipid-mobilizing activity of a synthetic peptide, NH2-Phe-Glu-Glu-Ala-Tyr-Ile-Pro-Lys-Glu-Gln-Lys-Tyr-Ser-Phe-COOH, corresponding to the 31-44 amino-acid sequence of human growth hormone, was studied.
(15) The study of the drugs effective in the treatment of cognitive deficits and memory loss associated with senile dementia of the Alzheimer's type--tacrine and amiridin, acetylcholinesterase inhibitor physostigmine and nootrop piracetam on uptake of 3H-serotonin (3H-5-HT), 3H-adrenaline (3H-AD), 3H-noradrenaline (3H-HA), 2H-dopamine (3H-DA), 3H-gamma-aminobutyric acid (3H-GABA), 3H-glutamic acid (3H-GLU), 3H-aspartic acid (3H-ASP) and 3H-glycine (3H-GLI) showed that tacrine and amiridin (5 x 10(-5) M) statistically significantly (P less than 0.05) inhibited the uptake of 3H-DA and 3H-5-HT.
(16) 55% of the biliary radioactivity excreted in 24 h was unchanged irinotecan, 22% was EHCPT Glu, and 9% was EHCPT.
(17) The active-site aspartic acid residue, Asp-362, of Escherichia coli citrate synthase was changed by site-directed mutagenesis to Glu-362, Asn-362 or Gly-362.
(18) The replacements for Glu-43 (Asp, Gln, Asn, Ser, and Ala) both decreased the catalytic efficiency and changed the one- and two-dimensional NMR spectral properties of the mutant enzymes.
(19) Meanwhile, control peptide (Gly-Arg-Gly-Glu-Ser-Pro), which does not contain the crucial cell binding sequence, did not show any inhibitory effects.
(20) Similar to the action of DA, the DA D-1 receptor agonist (+)SKF-38393 generally potentiated the activation produced by glutamate (GLU) at low ejection currents (less than or equal to 5 nA); at higher ejection currents, it depressed 97% of the CPu neurons tested.
Slued
Definition:
(imp. & p. p.) of Slue
Example Sentences:
(1) To compare pathogenicity, an experimental infection was attempted in CF1 mice with a single dose of 1.5 x 10(7) organisms of both an ATCC standard strain and SLU isolate of E. rhusiopathiae.
(2) The purpose of this study was to determine whether endogenous CCK affects growth of the human cholangiocarcinoma, SLU-132.
(3) Exogenous high-dose CCK thus appears to increase production and release of CEA from SLU-132; it also appears to retard growth of this tumor line in the nude mouse.
(4) The study was called the SLU-project (Skolöverstyrelsens och Lärarhögskolans Utvecklingsprojekt) and the main purpose was to study physical and mental growth during puberty as well as heredity and environment influences on these growth processes.
(5) Cholestyramine significantly inhibited the growth of SLU-132 and stimulated growth of the normal pancreas.
(6) Two of these genes, SLU4 and SLU7 (SLU: synergistic lethal with U5 snRNA), encode products required for the second catalytic step of splicing.
(7) Since cholecystokinin (CCK) promotes growth of normal biliary tract, we sought to determine whether CCK affects the growth and metabolism of human cholangiocarcinoma line SLU 132.
(8) Operative mortality was SLU 2.3%, VA 5.6% (p < 0.05).
(9) In a previous Swedish twin project (the SLU-project), approximately 300 MZ and DZ twin pairs and controls were followed through the Swedish compulsory school from grade 3 to grade 9.
(10) One year graft patency was SLU 87%, VA 71%; all grafts patent SLU 76%, VA 54%; at least one graft patent SLU 96%, VA 89%.
(11) In 1979, SLU launched a Mobile Nursing Clinic, a primarily staffed by nurses.
(12) In one of these tumors (SLU 077), serum carcinoembryonic antigen (CEA) levels paralleled the tumor volumes.
(13) SLU patients free of myocardial infarction five years postoperatively was 83%.
(14) In this pilot-study, we have made a follow-up of the original SLU-sample after 20 years.
(15) Comparing 1972-74 SLU results to VA medical and surgical groups, CABG prolonged life in patients with double and triple vessel disease and in those completely revascularized.
(16) Pure cultures of Erysipelothrix rhusiopathiae (SLU isolate) were recovered from heart blood, liver, spleen and lungs.
(17) Comparative cumulative four year survivals were: [Table: see text] Cumulative four-year survival in 272 SLU patients (79%) completely revascularized was 94%, compared to SLU entire group of 95%, VA medical 86% (p < 0.002) and VA surgical 85% (p < 0.002).
(18) Perioperative myocardial infarction rate was SLU 8.4%, VA 18% (p < 0.005).
(19) From January 1972 through December 1974, at Saint Louis University Medical Center (SLU), 345 patients similar to those of the VA Cooperative Coronary Artery Study received CABG.
(20) Exogenous administration of cholecystokinin (CCK) or caerulein inhibits growth of SLU-132, a human cholangiocarcinoma that we have shown to possess receptors for CCK.