(v. t.) To swallow, or to swallow greedlly; to gorge.
(v. t.) To fill to satiety; to satisfy fully the desire or craving of; to satiate; to sate; to cloy.
(v. i.) To eat gluttonously or to satiety.
(n.) That which is swallowed.
(n.) Plenty, to satiety or repletion; a full supply; hence, often, a supply beyond sufficiency or to loathing; over abundance; as, a glut of the market.
(n.) Something that fills up an opening; a clog.
(n.) A wooden wedge used in splitting blocks.
(n.) A piece of wood used to fill up behind cribbing or tubbing.
(n.) A bat, or small piece of brick, used to fill out a course.
(n.) An arched opening to the ashpit of a klin.
(n.) A block used for a fulcrum.
(n.) The broad-nosed eel (Anguilla latirostris), found in Europe, Asia, the West Indies, etc.
Example Sentences:
(1) In attempts to correlate GLUT-1 and GLUT-2 expression to beta-cell function glucose uptake and glucose-stimulated insulin release in fresh and cultured islets were measured.
(2) Supermarkets are slashing the price of cauliflower because a relatively warm start to the year has produced a glut of florets.
(3) Thus, pretranslational suppression of GLUT 4 transporter gene expression may be an important mechanism that produces and maintains cellular insulin resistance in NIDDM.
(4) Following micropressure application of glutamate (500 microM) in stratum lacunosum-moleculare (L-M), inhibitory postsynaptic potentials (glut-IPSPs) were recorded in CA1 pyramidal cells.
(5) The GLUT 7 sequence is six amino acids longer than rat liver GLUT 2, and the extra six amino acids at the C-terminal end contain a consensus motif for retention of membrane-spanning proteins in the endoplasmic reticulum.
(6) The results indicate that the embryonic heart is rich in GLUT-1 mRNA; whereas the adult heart contains predominantly GLUT-4 mRNA.
(7) In the ZDF rat, a model of NIDDM that closely resembles the human syndrome, we have previously reported profound underexpression of GLUT-2, the high-Km facilitative glucose transporter expressed by beta cells of normal animals.
(8) GLUT 2 occurred in all hepatocytes as a basolateral membrane protein with a gradient of high expression in the periportal area and a lower one in the perivenous part.
(9) In heart, GLUT-4 mRNA decreased to a greater extent than GLUT-4 protein in response to diabetes and fasting.
(10) Both GLUT-1 and GLUT-4 isoform content were greater in red than white muscle.
(11) No change in the level of GLUT-4 mRNA was detected in the plantaris muscle although increases were observed in the soleus muscle from the obese rats.
(12) AspT mRNA is widely distributed in the brain, but is present at high levels in GABAergic neuronal populations, some that may be glutamatergic, and in a subset of neurons which do not contain significant levels of either GAD or GluT mRNA.
(13) At higher doses (0.1-0.4 M), Glut induced hypotension with bradycardia in 23 out of 40 injections in both pons and MMRF.
(14) Western blot assay of GLUT-4 (a major isoform of glucose transporter in adipocytes) indicated that FITC (a) partially blocked insulin-dependent translocation of GLUT-4 from the intracellular site to the plasma membrane while it (b) induced a mild "insulin-like" effect.
(15) The increase of the GLUT-4 mRNA and the decrease in the GLUT-4 protein correlated with the rate of glucose uptake [correlation coefficient (r) = -0.55, P less than 0.01, and r = -0.44, P less than 0.05, respectively].
(16) In addition, both D-galactose and D-mannose are transported by GLUTs 1-3 at significant rates; furthermore, GLUT 2 is capable of transporting D-fructose.
(17) The amount or activity and the mRNA concentrations of Glut 4, fatty acid synthase (FAS) and acetyl-CoA carboxylase (ACC) were measured before and after weaning in white adipose tissue of obese and lean Zucker rats.
(18) In contrast, chronic insulin infusion into nondiabetic rats does not affect the number of hepatocytes expressing GLUT-1.
(19) Local application of glutamate (GLUT) reliably excited cells of the supraoptic nucleus.
(20) ASP and GLUT depolarized reversibly the cell membrane and increased its conductance.
Surfeit
Definition:
(n.) Excess in eating and drinking.
(n.) Fullness and oppression of the system, occasioned often by excessive eating and drinking.
(n.) Disgust caused by excess; satiety.
(v. i.) To load the stomach with food, so that sickness or uneasiness ensues; to eat to excess.
(v. i.) To indulge to satiety in any gratification.
(v. t.) To feed so as to oppress the stomach and derange the function of the system; to overfeed, and produce satiety, sickness, or uneasiness; -- often reflexive; as, to surfeit one's self with sweets.
(v. t.) To fill to satiety and disgust; to cloy; as, he surfeits us with compliments.
Example Sentences:
(1) I'm reminded of something Cooper said earlier, when talking about the pressures of this time of year for working parents, with its surfeit of plays and, "Oh God, not another school fair".
(2) This very tight clustering suggests a cis interaction between adjacent Surfeit genes.
(3) The clustered arrangement (no two adjacent genes are separated by more than 73 base pairs [bp] and two genes overlap by 133 bp at their 3' ends) of the four genes (Surf-1 to -4) identified so far in the mouse surfeit locus (T. Williams, J. Yon, C. Huxley, and M. Fried, Proc.
(4) The organization of the mouse surfeit locus is unusual in that it contains six housekeeping genes (Surf-1-Surf-6), which are unrelated by sequence homology, in the tightest mammalian gene cluster thus far described.
(5) When the faculty status of women and men academic anesthesiologists was examined a significant difference was found in rank distribution in age groups 40 to 44 (P less than 0.005) and 45 to 49 (P less than 0.001), where there was a deficit of professors and a surfeit of instructors among women.
(6) Here's Niall Mullen: "As a Liverpool fan who can barely buy his own groceries I am going to be outraged, outraged I tell you, if we fail to procure a player I've never heard of, who plays in a position in which we have a surfeit of players, for a club I've never seen play."
(7) We found no evidence of an initial surfeit of processing units, dendritic branches, or synapses.
(8) In this endocrine control, the renin axis provides the primary defence against sodium volume depletion and hypotension while atrial hormone plays an increasingly active counter-role for coping with situations that involve a sodium-volume surfeit or rising blood volume or blood pressure levels.
(9) Profound changes are occurring in the health care system, including a surfeit of physicians, cost containment, and competition.
(10) Using an interspecies backcross, we have mapped the HOX-5 and surfeit (surf) gene clusters within the proximal portion of mouse chromosome 2.
(11) In the adult, sodium surfeit is associated with an increase in urinary dopamine; the opposite occurs in the young.
(12) But we've had a surfeit of "behind the scenes" pictures of both coalition leaders; too many pictures of Cameron gurning at his new baby have led to this sort of material becoming a devalued currency.
(13) Responses to the energy surfeit led to intakes 104% and 116% of baseline, respectively.
(14) Since a repository would be expected to accumulate surplus material, one would predict that phosphorylase, which contains stoichio-metric amounts or pyridoxal phosphate, would increase in muscle of animals surfeited with the vitamin.
(15) What is called progress seems often to bring a surfeit of new experiences, facts, machines, noises, producing a feeling of helplessness, almost of despair.
(16) These data support the hypothesis that a surfeit of opioidergic ligand may potentiate drinking of alcoholic beverages.
(17) The concept of a basal level of body sodium (Strauss' state 'between surfeit and deficit') was studied by means of body sodium measurements in rats on different sodium intakes, in some cases after diuretic pretreatment.
(18) The invading fibers appear to encounter resistance at the basal lamina, but, once within the epithelium, at embryonic days 8-9, they form a surfeit of branches in columnar zones oriented radially toward the surface.
(19) Relative to their energy consumption on the medium-fat diet, the subjects spontaneously consumed an 11.3% deficit on the low-fat diet and a 15.4% surfeit on the high-fat diet (p less than 0.0001), resulting in significant changes in body weight (p less than 0.001).
(20) The mouse surfeit locus is unusual in that it contains a number of closely clustered genes (Surf-1, -2, and -4) that alternate in their direction of transcription (T. Williams, J. Yon, C. Huxley, and M. Fried, Proc.