(1) Superoxide dismutase (SOD) activity and its concentration were measured in thyroid tissues obtained from patients with Graves' disease, Hashimoto's thyroiditis, differentiated thyroid cancer, and endemic goiter (before and after iodine supplementation) as well as in normal thyroid tissue (paranodular tissue) from patients with follicular adenomas.
(2) A total of 5.8% abnormalities were found including nodular disease, thyroiditis, Graves' disease, hypothyroidism, simple goiter, and iatrogenic hyperthyroidism.
(3) Small oval cysts (less than or equal to 1 cm) with strong echo were all diagnosed colloid goiter.
(4) Levothyroxine therapy lowered the monoiodotyrosine and diiodotyrosine levels, ameliorated all her endocrinopathies, started her periods, and shrank the goiter.
(5) Rather, there was diffuse thyroidal hyperplasia of the micronodular variety, consistent with multinodular toxic goiter.
(6) The histological picture of the goiters was similar to that found in thiourea-treated teleosts and thiouracil-treated mammals.
(7) The data obtained suggest that the alkaline subfraction is characterized by an increased rigidity and apparently by altered structural properties in toxic goiter.
(8) The tumors included one goiter and one Hürthle cell adenoma, one lymphoma, one medullary carcinoma, two Hürthle cell cancers, and five papillary cancers, varying widely in clinical staging and histologic differentiation.
(9) The high incidence of goiter in older patients is probably due to insufficient iodine intake in youth.
(10) The increased functional activity of the endothelium, thinner walls of capillaries and the appearnace of a greater amount of fenestrations against the background of the thyroid stimulation are likely to be factors contributing to penetration of non-hormonal iodine products (iodine tyrosines and products of incomplete hydrolysis of thyroglobulins) into the circulation, which can be observed under certain pathological conditions accompanied by increased thyrotropic stimulation--such as diffused toxic goiter and diffuse non-toxic goiter.
(11) The long-term follow-up (up to 30 years) of the patients with reoperations for GATG recurrences, or subsequent development of a "goiter" has shown that GATG presented a metastasis of papillary thyroid cancer into the lateral lymph nodes of a neck.
(12) Of various possibilities analyzed, only a small goiter at the onset of therapy and tri-iodothyronine toxicosis were significantly favorable prognostic indicators that a remission would be maintained.
(13) Aim of this report is a stress of over-hasty classification to the surgical treatment of goiter diagnosed as hyperactive.
(14) Females of all ages had a higher prevalence of goiter than did males.
(15) To determine whether differences in TSH receptors could account for the differences in AC activity, we studied the 8000 g membrane particulate fraction from 28 thyroid tissues (10 papillary carcinomas, 6 multinodular goiters, 4 follicular adenomas, 3 follicular carcinomas, 2 Graves, 1 normal, 1 Hürthle cell adenoma, and 1 thyroiditis).
(16) The unusual case of a patient with goiter and left faciobrachiocrural paresis due to right temporoparietal infarction is reported.
(17) Iodine balance during pregnancy and lactation was investigated by measuring iodine concentration in the urine of 11 pregnant women, born and living in a moderately iodine deficient endemic goiter area in Northeastern Sicily, collected during the last week of pregnancy, and between the 5th and 7th day after delivery, and in their milk sampled simultaneously with the urine of their newborns.
(18) The child showed two types of signs : respiratory distress due to higher neurological disorders and a multinodular, non-compressing goiter.
(19) Benign disease was diagnosed in 345 patients (232 with benign nodular goiter, 98 with lymphocytic thyroiditis, three with granulomatous thyroiditis, and 12 with cysts).
(20) The knowledge of the anterior adjacent lamellae of the throat is very important for surgery of the goiter and parathyroid glands.
Goitrous
Definition:
(a.) Pertaining to the goiter; affected with the goiter; of the nature of goiter or bronchocele.
Example Sentences:
(1) Histopathological studies on goitrous tissue and iodine estimations on body fluids confirmed that the goiter in Tasmania is typical of endemic goiter, which is usually attributed to iodine deficiency.
(2) In order to find out whether different HLA associations with the disease may be found in different ethnic groups, we have now typed 68 patients with autoimmune goitrous thyroiditis from Eastern Hungary for HLA-A, -B, -C, and -DR antigens; 66 of these patients were also typed for IgG heavy-chain markers (Gm).
(3) Three other subjects were goitrous and euthyroid (one with a positive PDT), and the remaining five sibs were euthyroid with a presumably normal thyroid.
(4) Moreover, in 14 goitrous patients with biopsy-proved chronic thyroiditis with negative HA results, 12 (86%) showed abnormal high TgAb levels.
(5) The incorporation in incubated slices of [(14)C]proline and [(14)C]leucine into soluble proteins precipitated by 35-42%-saturated ammonium sulphate was markedly lower in goitrous tissue.
(6) We have conducted biochemical and genetic studies in five unrelated families (denoted A, C, R, P, and G), which included nine goitrous subjects (five borderline euthyroid and four hypothyroid) with complete (n = 6) or partial (n = 3) thyroid peroxidase (TPO) deficiency.
(7) Sixty-six per cent of females and 54 per cent of males were goitrous.
(8) In addition the goitre extract contained iodoproteins which had the immunological properties of serum albumin and immunoglobulin G. Determination of the iodine and iodoamino acid content of the hydrolysed iodoproteins revealed that they contained iodothyronines which were able to contribute to the production of thyroid hormones although the total iodothyronine content of the goitrous gland was less than that of the normal sheep thyroid gland.
(9) There are two forms of autoimmune thyroiditis that may cause hypothyroidism: autoimmune atrophic thyroiditis (primary idiopathic hypothyroidism or primary myxedema) and autoimmune goitrous thyroiditis (Hashimoto's disease).
(10) No differences in circulating thyroid hormone pattern were found among goitrous and nongoitrous subjects.
(11) The non-hormonal iodine of the serum of goitrous sheep appeared to include iodotyrosines and iodinated protein.
(12) The patients were divided into two subgroups according to the anatomo-pathological finding and ensuing type of goiter resection (either selective ablation of non-functioning parenchyma with normal remnants, or resection of functioning and non-functioning parenchyma in the presence of goitrous remnants); the postoperative increase in the mean basal and TRH-stimulated serum TSH values was significant only in the non-selective ablation subgroup.
(13) In the present study T3, T4, TSH serum concentrations were measured in 166 subjects whose goiter grading was ascertained according to WHO classification; 39 of them had no goiter (grading 0), 127 were goitrous with a grading comprised between 1a and 4.
(14) The elevated activity in goitrous tissue was manifested by an increase in V for histone, ATP, Mg2+ and cyclic AMP, with no change in the apparent Km.
(15) Starch-gel-electrophoretic separations of sera from normal and goitrous sheep after (131)I injection (100-500muc) showed no qualitative differences in the radioactivity of protein components.
(16) The concentration of circulating thyroid-stimulating hormone was significantly higher (P<0.01 in three sheep, P<0.05 in one sheep) in goitrous sheep.
(17) Therefore, IgG from hypothyroid patients with goitrous Hashimoto's thyroiditis mainly suppressed 125I thyroidal uptake, rather than inhibiting thyroid peroxidase activity.
(18) In the 5 goitrous patients, patterns of recovery of pituitary and thyroid function assessed by the same parameters were much less consistent.
(19) To this purpose TSH-BAb were evaluated in a group of 140 consecutive patients with autoimmune thyroiditis, which included 26 cases of AT and 114 subjects with goitrous Hashimoto's thyroiditis (HT); among the goitrous group 27 were euthyroid (HT-E), 32 had subclinical hypothyroidism (HT-SH), and 55 had clinical hypothyroidism (HT-H).
(20) We measured thyroid hormones and TSH in cord blood and TSH in newborn's blood from dry blood spots on filter paper in 5-14 th days, from 58 non goitrous and 61 goitrous mothers.