(1) Although GORD is primarily a motor disorder, the injurious effects of gastric acid are central to the pathogenic process of oesophagitis, and the severity of disease correlates with the degree and duration of oesophageal acid exposure.
(2) The ambulatory 24 hour pH test may have rendered the AP test obsolete in the assessment of GORD as the cause of NCCP.
(3) Epidemiological studies of gastro-oesophageal reflux disease (GORD) are confounded by the lack of a standardized definition and a diagnostic 'gold-standard' for the disorder.
(4) Using 24 hour pH monitoring as a reference standard, the usefulness of the acid perfusion (AP) test in predicting gastro-oesophageal reflux disease (GORD) was assessed in 71 non-cardiac chest pain (NCCP) patients and 23 endoscopic oesophagitis patients.
(5) This may be made worse by relative gastric acid hypersecretion in some patients with severe GORD.
(6) The aim of this study was to investigate the association of gastro-oesophageal reflux disease (GORD) with radiographic pulmonary changes.
(7) The pathogenesis of GORD depends on a mix of factors which vary amongst individual patients.
(8) In the NCCP population with a normal oesophageal examination (1) AP test reproduction of chest pain is poorly predictive of GORD; (2) AP test reproduction of heartburn is more predictive of GORD but does not ensure that the chest pain is caused by GORD; (3) a negative AP test does not exclude GORD and (4) only 48% of AP test positive patients have demonstrable acid mediated chest pain.
(9) Although these data are not conclusive, it seems prudent, if possible, to avoid the use of NSAIDs in patients with GORD, particularly those with oesophageal stricture.
(10) In patients with more severe grades of oesophagitis, there are abnormally high levels of nocturnal acid exposure, with the intra-oesophageal pH being less than 4.0 for 36% of the time, compared with 5% of the time in patients with mild GORD.
(11) In Western countries, 20-40% of the adult population experience heartburn, which is the cardinal symptom of GORD, but only some 2% of adults have objective evidence of reflux oesophagitis.
(12) Of patients with oesophagitis 29% had no typical symptoms of GORD; only 24% of patients with regurgitation had oesophagitis.
(13) Although GORD causes substantial morbidity, the annual mortality rate due to GORD is very low (approximately 1 death per 100,000 patients), and even severe GORD has no apparent effect on longevity, although the quality of life can be significantly impaired.
(14) A third of the patients reported such inconclusive symptomatology at history-taking that no preliminary diagnosis about the presence or absence of GORD could be made.
(15) The limited information available about salivation in GORD patients suggests that salivary secretion is no different from that of age-matched controls, but that there is an age-dependent loss of the salivary response to oesophageal acidification.
(16) The long duration of action and effective inhibition of meal-stimulated acid secretion probably explains the superiority of omeprazole in treating GORD.
(17) In the 105 of these patients in whom there was any suspicion of GORD, 24-hour pH monitoring was carried out.
(18) When patients were divided according to their symptoms suggestive of GORD, lower VC%, FVC%, and FEV1% were found in patients with than in those without symptoms (87 vs 102, p = 0.0018; 76 vs 91, p = 0.0099; 80 vs 93, p = 0.0026).
(19) The signs and symptoms of GORD often wax and wane in intensity, and spontaneous remissions have been reported.
(20) Of several symptoms thought to be related to gastrooesophageal reflux disease (GORD), only heartburn (68% vs 48%) and acid regurgitation (60% vs 48%) occurred in more of the patients with GORD (as determined by pH monitoring) than of those with normal pH monitoring.
Gored
Definition:
(imp. & p. p.) of Gore
Example Sentences:
(1) But none of those calling on Obama to act carries the moral authority of Gore, who has devoted his post-political career to building a climate movement.
(2) With this announcement, the UK is demonstrating the type of leadership that nations around the world must take in order to craft a successful agreement in Paris and solve the climate crisis,” said former US vice-president Al Gore.
(3) Two of four Gore-Tex grafts in the low flow category failed within the first postoperative month.
(4) The public and private sectors alike must do what is necessary to stop global warming," Gore told the Guardian.
(5) Long before anyone had heard of Al Gore's An Inconvenient Truth, she planned to make a low-budget documentary about oil and climate change.
(6) These molecules may become highly substituted with phosphoglycerol moieties from the head group of phosphatidylglycerol; diglyceride is a by-product of this reaction (K. J. Miller, R. S. Gore, and A. J. Benesi, J. Bacteriol.
(7) The IPCC is charged with providing a scientific, balanced assessment about what's known and what's known about climate change There are lots of organisations ringing bells The IPCC is more like a belltower, which people can climb up to get a clear view 8.41am BST Al Gore , the former US vice-president and winner of the Nobel peace prize for his work on climate change , has responded to the IPCC report by saying it shows the need for a switch to low carbon sources of energy (note his emphasis is on mitigation, i.e.
(8) Having bought the album as a present for her 12-year-old daughter, Tipper Gore, wife of Al, was horrified by the lyrics to Darling Nikki.
(9) In the case of glass, Gore-tex, and Dacron, which are insoluble in the solvent of the coating solution, only a superficial layer of PUPA could be obtained.
(10) So we have opted instead to meet somewhere Thatchery: "her table" at the Goring Hotel in London, around the corner from her house in Chester Square.
(11) In 31 patients we implanted a teflon membrane (Gore-Tex) during flap operation for a duration of 6 weeks.
(12) In an echo of Al Gore's An Inconvenient Truth , which evolved from a slideshow presentation into a hit eco documentary, the prince's film is currently being shot in the US.
(13) Saying he had spoken to the president’s daughter a number of times since then, Gore added: “I thought that he would come to his senses on it, but he didn’t.
(14) Gore-Tex did not loose its structural integrity despite frank injection.
(15) Adhesions to the Gore-SM occurred at wrinkles in or at the edges of the membrane.
(16) No agreement is perfect, and this one must be strengthened over time, but groups across every sector of society will now begin to reduce dangerous carbon pollution through the framework of this agreement,” said Gore.
(17) Since 1984, percutaneous transluminal angioplasty (PTA) utilizing high pressure balloon catheters has been used as an initial approach to restore patency of PTFE (polytetrafluoroethylene, GORE-TEX) hemodialysis vascular access grafts.
(18) Intimal proliferation of musculoelastosis which was formed of longitudinal smooth muscle bundles and elastic fibers was characteristic in shunted patients, especially after the central palliation procedure, Waterston anastomosis or modified Blalock-Taussig (BT) anastomosis using the Gore-Tex tube graft.
(19) Frank Gore doesn't make it in to the endzone on first down.
(20) Over the decades, the Mauna Loa readings, made famous in Al Gore's documentary An Inconvenient Truth, show the CO2 level rising and falling each year as foliage across the northern hemisphere blooms in spring and recedes in autumn.