(n.) A constitutional disease, occurring by paroxysms. It consists in an inflammation of the fibrous and ligamentous parts of the joints, and almost always attacks first the great toe, next the smaller joints, after which it may attack the greater articulations. It is attended with various sympathetic phenomena, particularly in the digestive organs. It may also attack internal organs, as the stomach, the intestines, etc.
(n.) A disease of cornstalks. See Corn fly, under Corn.
(n.) Taste; relish.
Example Sentences:
(1) In 8 patients with gout and 11 patients with pseudogout synovial fluid and small tissue specimens could be obtained with the aid of the Parker-Pearson needle.
(2) Both patients are likely to be sporadic cases of familial nephropathy with gout, an autosomal dominant disease, due to a new mutation.
(3) Conversely, crystalline protein binding may be a critical factor in the pathogenesis of gout, and the presence of abnormal proteins in RA could protect against gout.
(4) Tissue degeneration in gout clearly follows (tophaceous) crystal deposition.
(5) Five of our 7 patients had a positive family history of tics, and 2 a confirmed family history of gout.
(6) A 30-year-old man had a recurrent painful calf swelling associated with gout that mimicked thrombophlebitis and possibly muscle tear.
(7) Sclerosed areas with scarce and plump villi as well as sometimes hyperplastic and polymorphous synovial cell layers could be demonstrated histologically in the tissue specimens of the needle biopsies in cases with gout.
(8) Significantly more treated patients than control subjects showed evidence of a high serum creatinine level, mild hypokalemia, and gout.
(9) A many-year investigation of 254 primary gout patients aged 21 to 78 was carried out to reveal characteristic features of a course of gout under present-day conditions.
(10) The history of saturnine gout is almost as old as civilization itself.
(11) Intra- as well as extracellular crystals could also be demonstrated with the aid of scanning electron microscopy in sediments of synovial fluid in gout and pseudogout.
(12) A study of the level of beta 2-microglobulin (beta 2-MG) in the blood serum and urine was conducted in 67 patients: 22 with chronic pyelonephritis, 13 with gout with renal lesion, 25 with chronic glomerulonephritis (5 without hyperuricemia, 20 with hyperuricemia) and 7 with amyloidosis accompanied mainly by renal lesion.
(13) Naproxen is a useful alternative agent for the treatment of acute gout.
(14) A 65-year-old man with gout and renal dysfunction had taken 1 mg of colchicine daily for 3 years.
(15) In 1988 Abbot could prove that among men, those afflicted by gout as compared to those without gout experienced a 60% excess of coronary heart disease.
(16) The authors presented the results of a 5-year follow-up of 50 gout patients who had been regularly (no less than 3-4 times a year) examined in outpatient clinics.
(17) A high prevalence of gout among workers of the mining industry and early age at the onset of disease suggest probable association of gout with some industrial factors (manganese, tungsten, molybdenum, bismuth).
(18) For the great majority of patients with uncomplicated hypertension, without a previous myocardial infarction, congestive heart failure, diabetes mellitus or gout, thiazide diuretics appear to be both safe and effective antihypertensive agents.
(19) Ten years ago, we studied the clinical and radiographic manifestations of gout in 60 patients and described 3 patterns of disease.
(20) John Harvey Kellogg, the inventor of Corn Flakes, also invented the sunbed, patenting his first device in 1896 – by royal appointment no less, as Edward VII apparently kept one at Windsor Castle for his gout.
Goutiness
Definition:
(n.) The state of being gouty; gout.
Example Sentences:
(1) Low density lipoprotein (LDL) is the major plasma inhibitor of neutrophil oxidative and lytic responses to monosodium urate crystals and may function to modulate acute gouty inflammation.
(2) Thus, acute gouty arthritis is now recognized as an example of "crystal induced" synovitis.
(3) By the mid 20th century, however, the apparent decline of the gout in Europe and North America and the breakup of the gouty diathesis in those lands had been more than compensated by their large-scale reappearance in the Maori and in other indigenous inhabitants of the Pacific Basin who, at first sight, appeared to have become one large gouty family.
(4) Fifteen cases of acute gouty bursitis were seen among 136 crystal-proved cases of gout.
(5) Tenoxicam administered orally, rectally or parenterally is an effective analgesic and anti-inflammatory agent for the symptomatic treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and various rheumatic conditions such as tendinitis, bursitis, sciatica, back pain and gouty arthritis.
(6) The authors emphasize that the possibility of a septic arthritis should always be considered in the gouty patient, and not only in the elderly, as stressed in the literature, but also in younger patients.
(7) Many patients have gouty symptoms, especially after treatment with Busulfan, and many have an unexplained hemorrhagic tendency, making major operations a risk.
(8) Synovial fluids from 75 patients were analyzed, comprising the following disease groups: i) rheumatoid arthritis (n = 42), ii) osteoarthritis (n = 20), iii) gouty arthritis (n = 5), and iv) reactive arthritis (Reiter's disease, n = 8).
(9) One patient did not take any medical treatment and died suddenly when he was 19 years old, but showed no gouty signs.
(10) This latter observation raises doubts about the postulated physiological role of LDL in terminating the acute gouty attack.
(11) A double-blind study was carried out to compare the effects of ketoprofen and phenylbutazone in acute gouty arthritis.
(12) This suggests that the amount of LDL coating intraarticular urate crystals could vary during the course of a gouty paroxysm.
(13) In the case of two gouty groups divided according to the existence of gouty heredity, tophi or renal impairment, adenosine deaminase and inosine phosphorylase activity in the two groups were not significantly different.
(14) The data suggest an increase in the rate of purine turnover in aging gouty fibroblasts compared with normal fibroblasts.
(15) The case emphasized that patients with this deficiency may escape diagnosis during childhood and that internists should consider the diagnosis in adolescents or young adults with acute gouty arthritis or tophaceous gout.
(16) A rare case of gouty tophus localized to the temporomandibular joint is reported on by which alimentary troubles were caused.
(17) Monosodium urate (MSU)-induced synovitis in the dog's stifle (knee joint) is similar to an acute gouty attack in man in which a loss of function of the joint correlates with massive influx of neutrophils and the release of an assortment of inflammatory mediators (e.g.
(18) These findings suggest that the association of membranous nephropathy should be considered in patients with gout having moderate to severe proteinuria and that RTE may be involved in the pathogenesis of subepithelial deposits in gouty membranous nephropathy.
(19) (3) Synovial fluid from one gouty patient accelerated urate nucleation, while that from one rheumatoid patient inhibited nucleation.
(20) Striking elevations were also present in 2 patients who had acute gouty arthritis.