(n.) A constitutional disease, occurring by paroxysms. It consists in an inflammation of the fibrous and ligamentous parts of the joints, and almost always attacks first the great toe, next the smaller joints, after which it may attack the greater articulations. It is attended with various sympathetic phenomena, particularly in the digestive organs. It may also attack internal organs, as the stomach, the intestines, etc.
(n.) A disease of cornstalks. See Corn fly, under Corn.
(n.) Taste; relish.
Example Sentences:
(1) In 8 patients with gout and 11 patients with pseudogout synovial fluid and small tissue specimens could be obtained with the aid of the Parker-Pearson needle.
(2) Both patients are likely to be sporadic cases of familial nephropathy with gout, an autosomal dominant disease, due to a new mutation.
(3) Conversely, crystalline protein binding may be a critical factor in the pathogenesis of gout, and the presence of abnormal proteins in RA could protect against gout.
(4) Tissue degeneration in gout clearly follows (tophaceous) crystal deposition.
(5) Five of our 7 patients had a positive family history of tics, and 2 a confirmed family history of gout.
(6) A 30-year-old man had a recurrent painful calf swelling associated with gout that mimicked thrombophlebitis and possibly muscle tear.
(7) Sclerosed areas with scarce and plump villi as well as sometimes hyperplastic and polymorphous synovial cell layers could be demonstrated histologically in the tissue specimens of the needle biopsies in cases with gout.
(8) Significantly more treated patients than control subjects showed evidence of a high serum creatinine level, mild hypokalemia, and gout.
(9) A many-year investigation of 254 primary gout patients aged 21 to 78 was carried out to reveal characteristic features of a course of gout under present-day conditions.
(10) The history of saturnine gout is almost as old as civilization itself.
(11) Intra- as well as extracellular crystals could also be demonstrated with the aid of scanning electron microscopy in sediments of synovial fluid in gout and pseudogout.
(12) A study of the level of beta 2-microglobulin (beta 2-MG) in the blood serum and urine was conducted in 67 patients: 22 with chronic pyelonephritis, 13 with gout with renal lesion, 25 with chronic glomerulonephritis (5 without hyperuricemia, 20 with hyperuricemia) and 7 with amyloidosis accompanied mainly by renal lesion.
(13) Naproxen is a useful alternative agent for the treatment of acute gout.
(14) A 65-year-old man with gout and renal dysfunction had taken 1 mg of colchicine daily for 3 years.
(15) In 1988 Abbot could prove that among men, those afflicted by gout as compared to those without gout experienced a 60% excess of coronary heart disease.
(16) The authors presented the results of a 5-year follow-up of 50 gout patients who had been regularly (no less than 3-4 times a year) examined in outpatient clinics.
(17) A high prevalence of gout among workers of the mining industry and early age at the onset of disease suggest probable association of gout with some industrial factors (manganese, tungsten, molybdenum, bismuth).
(18) For the great majority of patients with uncomplicated hypertension, without a previous myocardial infarction, congestive heart failure, diabetes mellitus or gout, thiazide diuretics appear to be both safe and effective antihypertensive agents.
(19) Ten years ago, we studied the clinical and radiographic manifestations of gout in 60 patients and described 3 patterns of disease.
(20) John Harvey Kellogg, the inventor of Corn Flakes, also invented the sunbed, patenting his first device in 1896 – by royal appointment no less, as Edward VII apparently kept one at Windsor Castle for his gout.
Urate
Definition:
(n.) A salt of uric acid; as, sodium urate; ammonium urate.
Example Sentences:
(1) Furthermore, blood pressure, free fatty acid concentration, liver enzymes, and urate concentrations were significantly correlated with glucose infusion rate at the clamp test.
(2) Urinary urate crystalluria was prominent in each infant in the first few days after the onset of diuresis, during which normal serum urate concentrations and normal renal function were established.
(3) Urate oxidase from hog liver (urate: oxygen oxidoreductase, EC 1.7.33) has been entrapped in a crosslinked 2-hydroxyethyl methacrylate gel with a 47% retention of activity.
(4) Thirty-eight fluids were found to have crystals (monosodium urate (MSU) in 15, calcium pyrophosphate dihydrate (CPPD) in 5, CPPD plus apatite-like crystals in 9, apatite-like clumps alone in 8 and lipid liquid in 1).
(5) This previously unreported association of a high PZA-nonsuppressible urate excretion with a postprobenecid urate clearance exceeding glomerular filtration rate suggests that a combined renal tubular defect is responsible for hypouricemia.
(6) Plasma levels of both phosphorus and urate fell during this time.
(7) The inhibiting activity of CaOx crystal growth and the most widely accepted inhibitors (glycosaminoglycans, citrate, magnesium, pyrophosphate), stone constituents (calcium, oxalate, phosphate, urate) and other normal urinary substances were evaluated.
(8) Mitochondrial substrates (succinate, 2-oxoglutarate, NADH) in the presence or absence of ADP and Pi or peroxisomal substrates (glycollate, urate or ethanol) gave no increases in light emission by whole homogenates or in any of the fractions.
(9) The mean concentration of urate in the serum of 80 Dalmatian Coach Hounds was approximately double that in the serum of 99 dogs of other breeds.
(10) In the six other patients a hypouricaemic effect with increased urate clearance was noted.
(11) Vibratome sectons are incubated at 37 degrees C for 60 min in 0.1 M Pipes buffer, pH 7.8, containing 3 mM cerium chloride and 0.1 mM sodium urate.
(12) The [2-14C] urate uptake was more sensitive to unlabeled urate than to unlabeled xanthine and hypoxanthine.
(13) Urinary urate was slightly higher in the stone formers than in the normals but this was not statistically significant.
(14) Fructose caused an expansion of body urate pool in all subjects, while urate turnover was increased in four.
(15) Three main types are commonly found: calcium pyrophosphate, calcium hydroxyapatite and monosodium urate.
(16) To assess the risk of accumulation of adenosine degeneration products after several injections measurements were also made of hypoxanthine, xanthine and urate in plasma at intervals after the injections.
(17) Urate influx seems to depend on intracellular glycolysis.
(18) We discuss defects of several commercially available kits for determination of serum urate and recommend comparing results of these kits with results from the phosphotungstic acid method as a precaution against falsely low results.
(19) The optimal 2-oxoglutarate concentration for stimulating uptakes was 10 microM for PAH and 150 microM for urate.
(20) This 24 French instrument can be used in simultaneously with electrohydraulic lithotripsy (Urat I), i.e., stones of the size of a cherry can be simply punched, while all larger stones may be destroyed first by electrohydraulic lithotripsy and then cut into smaller pieces for removal with the punch.