(a.) Consisting of, or resembling, grains; as, a granular substance.
Example Sentences:
(1) The leukemic T-cells in two patients with chronic lymphocytic leukemia (CLL) had specific features of large granular lymphocytes (LGL), and those in two patients with acute lymphocytic leukemia (ALL) had L2 morphologic characteristics.
(2) Combined SEM and TEM examination of the endothelium of compressed segments revealed "craters" and "balloons", blebs and vacuoles, swollen mitochondria, dilated granular endoplasmic reticulum, and subendothelial edema.
(3) In situ hybridization of SMG sections showed that Aeg-1 and Aeg-2 transcripts are produced by the cells of granular convoluted tubules.
(4) In the terminal segment of the hamster epididymidis there was some evidence of micro-merocrine protein secretion a the level of the principal cells and clear evidence of granular secretion in the light cells, presumable of glycoproteins.
(5) Measurable quantities of temefos were found in the snails within 1 day after the first treatment with a 2% granular formulation but 3 weeks elapsed before uptake occurred following treatment with a temefos emulsion.
(6) Electron microscopic examination of all leptomeningeal and meningioma cultures revealed desmosomes and dense tonofilament formation; in addition, granular, filamentous basement membrane-like material was abundant in the extracellular spaces of all cultures.
(7) Cholecystokinin (CCK) as the sulfated (CCK-8S) and unsulfated (CCK-8U) octapeptide sequences, and CR 1409 were administered intraventricularly while the action potential (EAP) in the granular cell layer of the hippocampal dentate gyrus evoked by perforant path stimulation was recorded.
(8) The granules of human large granular lymphocytes have been reported to contain, in addition to perforin, a soluble HRF activity that can be eluted from anion-exchange columns at 115 mM NaCl.
(9) Moreover, it was more apparent in less differentiated tumors in which the granular pattern was often absent or inconsistent.
(10) Ultrastructural examination of noncartilaginous regions of the tumor demonstrated mesenchymal cells with features suggestive of cartilaginous differentiation, viz, scalloped cell membranes, sac-like distension of abundant rough endoplasmic reticulum, and a matrix containing fibrillary and finely granular material.
(11) As cyclic AMP-stimulated water flow and sodium transport are thought to occur in one cell type, the granular cells, distinct pools of cyclic AMP are thought to be present in one and the same cell type.
(12) The data obtained testify to the presence in the granular fraction of the endopeptidase LTH-converting activity which is sensitive to pepstatin A, an aspartyl proteinase inhibitor as well as to chelators and a serine proteinase inhibitor.
(13) In the advanced papilloma, cytolytic cells in the outer spinous and the granular layers did not stain positively with any of the three antibodies used.
(14) During the latest phase the periequatorial material is vanishing, the hyaloid capillaries disappear, the density of the posterior granular substance decreases.
(15) Culturing mononuclear cells from peripheral blood or bone marrow of leukemia patients with IL-2 resulted in an expansion of residual large granular lymphocytes and development of cytotoxic activity.
(16) The ultrastructural study of nucleoli and ribonucleoprotein-containing structures in human seminiferous tubules revealed that the nucleoli of spermatogonia, spermatocytes and Sertoli cells exhibited a tripartite structure consisting of: a fibrillar center, a compact granular portion, and a reticular portion containing both pars fibrosa and pars granulosa.
(17) This technique contrasted the fibrillar component and the granular component in interphase nucleoli as a reflection of the degree of packing.
(18) An enormous occurrence of granular endoplasmic reticulum in the intestinal cells of P. commutatus shows an excessive protein synthesis.
(19) Large aggregates of finely granular or filamentous material (nematosomes) were present in AD neurons.
(20) After incubation of cells in a fresh medium (in the course of 18, 24 hours) there occurs a total restoration of the ultrastructure of the nuclei, granular endoplasmatic reticulum, mitochondria, due to the repairing and strong intensification of synthetic processes, respiration and glycolysis, mitotic activity of the cells.
Pastille
Definition:
(n.) A small cone or mass made of paste of gum, benzoin, cinnamon, and other aromatics, -- used for fumigating or scenting the air of a room.
(n.) An aromatic or medicated lozenge; a troche.
(n.) See Pastel, a crayon.
Example Sentences:
(1) Validation studies, to show that the method is precise, accurate and rectilinear, have been carried out on four linctus formulations and two pastille formulations.
(2) This parallel, double-blind, randomized, placebo-controlled study evaluated the acceptance and effectiveness of the nystatin pastille at two different dosages.
(3) A selective high-performance liquid chromatographic procedure has been developed for the determination of the major Ipecacuanha alkaloids, emetine and cephaeline, in a number of linctus and pastille preparations.
(4) The potential for enhanced drug delivery to the oropharynx suggests that nystatin pastilles may be useful in patients in whom poor compliance seems likely.
(5) I think the very first case on was a 14- or 15-year-old who'd taken, I think it was something like two packets of Fruit Pastilles and a can of Coke from a small store in the city centre.
(6) The flavored pastille was well accepted by the subjects and both dosages were shown to be effective in significantly reducing or eliminating the Candida organism during active therapy.
(7) Fifty consecutive patients with respiratory diseases who developed oropharyngeal candidiasis were assessed clinically and microbiologically before and after seven days' treatment with nystatin suspension or pastilles (a new formulation).
(8) Sample preparation is simple, involving either straight dilution for linctus formulations or simple dissolutions for pastilles.
(9) Pastilles and suspension were equally efficacious both clinically and microbiologically.
(10) Nystatin has been formulated in the form of a flavored pastille (troche) as an alternative to the oral suspension.
(11) Asked if he wants to be prime minister, he tends to throw up chaff, saying that he is more likely to be reincarnated as a doughnut or a Rowntree's Fruit Pastille or whatever takes his fancy.
(12) The qualitative and quantitative composition of microflora was studied in fruit and vegetable juices, pastilles and sauces of sublimation drying.