What's the difference between grave and sad?

Grave


Definition:

  • (v. t.) To clean, as a vessel's bottom, of barnacles, grass, etc., and pay it over with pitch; -- so called because graves or greaves was formerly used for this purpose.
  • (superl.) Of great weight; heavy; ponderous.
  • (superl.) Of importance; momentous; weighty; influential; sedate; serious; -- said of character, relations, etc.; as, grave deportment, character, influence, etc.
  • (superl.) Not light or gay; solemn; sober; plain; as, a grave color; a grave face.
  • (superl.) Not acute or sharp; low; deep; -- said of sound; as, a grave note or key.
  • (superl.) Slow and solemn in movement.
  • (n.) To dig. [Obs.] Chaucer.
  • (n.) To carve or cut, as letters or figures, on some hard substance; to engrave.
  • (n.) To carve out or give shape to, by cutting with a chisel; to sculpture; as, to grave an image.
  • (n.) To impress deeply (on the mind); to fix indelibly.
  • (n.) To entomb; to bury.
  • (v. i.) To write or delineate on hard substances, by means of incised lines; to practice engraving.
  • (n.) An excavation in the earth as a place of burial; also, any place of interment; a tomb; a sepulcher. Hence: Death; destruction.

Example Sentences:

  • (1) A reduction in neonatal deaths from this cause might be expected if facilities for antenatal diagnosis and termination of pregnancy were made available, although this raises grave ethical problems.
  • (2) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
  • (3) A patient with previously treated follicular carcinoma of the thyroid developed Graves' disease with a high titre of thyroid-stimulating antibodies (TSAb).
  • (4) Gwendolen Morgan, the lawyer at Bindmans dealing with the case, said: "We have grave concerns about the decision to use this draconian power to detain our client for nine hours on Sunday – for what appear to be highly questionable motives, which we will be asking the high court to consider.
  • (5) Superoxide dismutase (SOD) activity and its concentration were measured in thyroid tissues obtained from patients with Graves' disease, Hashimoto's thyroiditis, differentiated thyroid cancer, and endemic goiter (before and after iodine supplementation) as well as in normal thyroid tissue (paranodular tissue) from patients with follicular adenomas.
  • (6) Many reports of thyroid stimulating immunoglobulins (TSI) in relation to treatment of Graves' disease have been published and with variable results concerning prediction of permanent remission or relapse after therapy.
  • (7) The Duke and Duchess of Cambridge stood among the graves on 4 August last year in a moving ceremony to mark the 100th anniversary of the outbreak of war.
  • (8) After violence had run its bloody course, the country’s rulers conceded it had been a catastrophe that had brought nothing but “grave disorder, damage and retrogression”.
  • (9) On the other hand, immunofluorescence in anterior pituitary cells was faint and detected in only 2 of 28 patients with Graves' disease (7.1%) after absorption of their sera with rat liver aceton powder.
  • (10) In conclusion, not only TBII but also T3 release-stimulating antibodies may occur in a minority of patients with long-term remission of Graves' hyperthyroidism.
  • (11) It is deeply moving hearing him talk now – as if from the grave – about a Christmas Day when he felt so frustrated and cut-off from his family that he had to go into the office to escape.
  • (12) His verdict of her that "she danced on the graves of her husband's victims.
  • (13) Thirty-eight bodies have been removed from the mass graves, but DNA tests have shown that none is that of a missing student.
  • (14) Posterior synechiae, pupil deformations, grave uveitis with hypotonia of 4-10 mm Hg are rapidly developing.
  • (15) Displacement of [125I]TSH bound to fat cell membranes by both Graves' Ig and unlabeled TSH were time and temperature dependent, with similar dissociation curves, suggesting a specific binding of Graves' Ig to the membrane sites related to the TSH receptor in the fat cells.
  • (16) We have obtained sera from 42 patients with active Graves' disease and no known connective tissue disorders.
  • (17) A total of 5.8% abnormalities were found including nodular disease, thyroiditis, Graves' disease, hypothyroidism, simple goiter, and iatrogenic hyperthyroidism.
  • (18) LATS was measured with the double isotope technique in IgG serum concentrates of 23 patients with Graves' disease before treatment and of 18 patients during treatment with carbimazole and triiodothyronine.
  • (19) To elucidate whether insulin-induced hypoglycemia enhances the release of beta-endorphin in man, plasma extracts obtained from healthy subjects and patients with Graves' disease before and 45 min after insulin injection were subjected to gel chromatography, and the fractions obtained were measured by RIA for beta-endorphin.
  • (20) From the findings of abnormalities in intrathyroidal T cell subsets, we suggest that the decrease in the function of suppressor T cells within the thyroids of Graves' disease patients may be due to a decrease in CD4+2H4+ cells within thyroid tissue.

Sad


Definition:

  • (supperl.) Sated; satisfied; weary; tired.
  • (supperl.) Heavy; weighty; ponderous; close; hard.
  • (supperl.) Dull; grave; dark; somber; -- said of colors.
  • (supperl.) Serious; grave; sober; steadfast; not light or frivolous.
  • (supperl.) Affected with grief or unhappiness; cast down with affliction; downcast; gloomy; mournful.
  • (supperl.) Afflictive; calamitous; causing sorrow; as, a sad accident; a sad misfortune.
  • (supperl.) Hence, bad; naughty; troublesome; wicked.
  • (v. t.) To make sorrowful; to sadden.

Example Sentences:

  • (1) She loved us and we loved her.” “We would have loved to have had a little grandchild from her,” she says sadly.
  • (2) Wimbledon said the world No1 Williams had been suffering from a viral illness and it was a sad and bizarre end to the American’s tournament, not to mention a worrying sight, seeing her hardly able to play.
  • (3) Sadly, the bullet will not only kill off Greece’s future in Europe.
  • (4) Calum MacLean, Grangemouth Petrochemicals chairman, says, “This is a hugely sad day for everyone at Grangemouth.
  • (5) Sadly, the Jewish fanatic who assassinated Rabin in 1995 achieved his broader aim of derailing the peace train.
  • (6) It also devalues the courage of real whistleblowers who have used proper channels to hold our government accountable.” McCain added: “It is a sad, yet perhaps fitting commentary on President Obama’s failed national security policies that he would commute the sentence of an individual that endangered the lives of American troops, diplomats, and intelligence sources by leaking hundreds of thousands of sensitive government documents to WikiLeaks, a virulently anti-American organisation that was a tool of Russia’s recent interference in our elections.” WikiLeaks last year published emails hacked from the accounts of the Democratic National Committee and John Podesta, chairman of Hillary Clinton’s election campaign.
  • (7) I watched as she made the briefest eye contact with me on their way back, the flicker of hurt and sadness in her eyes reflecting mine, before the shutters came down.
  • (8) Only at 3 days did total plasma volume of SAD rats show a modest reduction of about 16% (P less than 0.05 vs. sham-operated plus unoperated controls).
  • (9) These sad numbers show that more Washington spending, threats of higher taxes on small businesses, and excessive government regulations don't create a healthy environment for job growth," Boehner said.
  • (10) Thirty-two nursing students were shown silent films in which 10 normal and 10 schizophrenic women described a happy, sad, and an angry personal experience.
  • (11) World Wildlife Fund Great Barrier Reef campaigner Richard Leck said it was a sad day for the reef and anyone who cared about its future.
  • (12) It is so sad, we don’t let her go out even if the weather is nice,” he says.
  • (13) During interviews, married couples experiencing infertility reported emotional reactions such as sadness, depression, anger, confusion, desperation, hurt, embarrassment, and humiliation.
  • (14) Half of the rats in each group had SAD surgery 1 week prior to study.
  • (15) There’s an overwhelming sadness among kids like that who have been kept there for a very long time.
  • (16) It is sadly slightly the territory we have inherited,” he said.
  • (17) In a statement the family said they were left "extremely sad and disappointed" by the verdicts: "We appreciate the work and effort over the years since events on Broadwater Farm that night in trying to bring people to justice.
  • (18) Moreover, no differences were found in abnormal lung function patients with and those without SAD in demographic, clinical, roentgenologic, and serologic features and results of pulmonary function tests.
  • (19) It is sad that the BBC chose to give Nick Griffin a platform.
  • (20) The only thing I'd say is that I know, from people who've told me firsthand, that sadly mixed marriages can be a bit conflicted on everyday issues.

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