(v. t.) To clean, as a vessel's bottom, of barnacles, grass, etc., and pay it over with pitch; -- so called because graves or greaves was formerly used for this purpose.
(superl.) Of great weight; heavy; ponderous.
(superl.) Of importance; momentous; weighty; influential; sedate; serious; -- said of character, relations, etc.; as, grave deportment, character, influence, etc.
(superl.) Not light or gay; solemn; sober; plain; as, a grave color; a grave face.
(superl.) Not acute or sharp; low; deep; -- said of sound; as, a grave note or key.
(superl.) Slow and solemn in movement.
(n.) To dig. [Obs.] Chaucer.
(n.) To carve or cut, as letters or figures, on some hard substance; to engrave.
(n.) To carve out or give shape to, by cutting with a chisel; to sculpture; as, to grave an image.
(n.) To impress deeply (on the mind); to fix indelibly.
(n.) To entomb; to bury.
(v. i.) To write or delineate on hard substances, by means of incised lines; to practice engraving.
(n.) An excavation in the earth as a place of burial; also, any place of interment; a tomb; a sepulcher. Hence: Death; destruction.
Example Sentences:
(1) A reduction in neonatal deaths from this cause might be expected if facilities for antenatal diagnosis and termination of pregnancy were made available, although this raises grave ethical problems.
(2) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(3) A patient with previously treated follicular carcinoma of the thyroid developed Graves' disease with a high titre of thyroid-stimulating antibodies (TSAb).
(4) Gwendolen Morgan, the lawyer at Bindmans dealing with the case, said: "We have grave concerns about the decision to use this draconian power to detain our client for nine hours on Sunday – for what appear to be highly questionable motives, which we will be asking the high court to consider.
(5) Superoxide dismutase (SOD) activity and its concentration were measured in thyroid tissues obtained from patients with Graves' disease, Hashimoto's thyroiditis, differentiated thyroid cancer, and endemic goiter (before and after iodine supplementation) as well as in normal thyroid tissue (paranodular tissue) from patients with follicular adenomas.
(6) Many reports of thyroid stimulating immunoglobulins (TSI) in relation to treatment of Graves' disease have been published and with variable results concerning prediction of permanent remission or relapse after therapy.
(7) The Duke and Duchess of Cambridge stood among the graves on 4 August last year in a moving ceremony to mark the 100th anniversary of the outbreak of war.
(8) After violence had run its bloody course, the country’s rulers conceded it had been a catastrophe that had brought nothing but “grave disorder, damage and retrogression”.
(9) On the other hand, immunofluorescence in anterior pituitary cells was faint and detected in only 2 of 28 patients with Graves' disease (7.1%) after absorption of their sera with rat liver aceton powder.
(10) In conclusion, not only TBII but also T3 release-stimulating antibodies may occur in a minority of patients with long-term remission of Graves' hyperthyroidism.
(11) It is deeply moving hearing him talk now – as if from the grave – about a Christmas Day when he felt so frustrated and cut-off from his family that he had to go into the office to escape.
(12) His verdict of her that "she danced on the graves of her husband's victims.
(13) Thirty-eight bodies have been removed from the mass graves, but DNA tests have shown that none is that of a missing student.
(14) Posterior synechiae, pupil deformations, grave uveitis with hypotonia of 4-10 mm Hg are rapidly developing.
(15) Displacement of [125I]TSH bound to fat cell membranes by both Graves' Ig and unlabeled TSH were time and temperature dependent, with similar dissociation curves, suggesting a specific binding of Graves' Ig to the membrane sites related to the TSH receptor in the fat cells.
(16) We have obtained sera from 42 patients with active Graves' disease and no known connective tissue disorders.
(17) A total of 5.8% abnormalities were found including nodular disease, thyroiditis, Graves' disease, hypothyroidism, simple goiter, and iatrogenic hyperthyroidism.
(18) LATS was measured with the double isotope technique in IgG serum concentrates of 23 patients with Graves' disease before treatment and of 18 patients during treatment with carbimazole and triiodothyronine.
(19) To elucidate whether insulin-induced hypoglycemia enhances the release of beta-endorphin in man, plasma extracts obtained from healthy subjects and patients with Graves' disease before and 45 min after insulin injection were subjected to gel chromatography, and the fractions obtained were measured by RIA for beta-endorphin.
(20) From the findings of abnormalities in intrathyroidal T cell subsets, we suggest that the decrease in the function of suppressor T cells within the thyroids of Graves' disease patients may be due to a decrease in CD4+2H4+ cells within thyroid tissue.
Tone
Definition:
(n.) Sound, or the character of a sound, or a sound considered as of this or that character; as, a low, high, loud, grave, acute, sweet, or harsh tone.
(n.) Accent, or inflection or modulation of the voice, as adapted to express emotion or passion.
(n.) A whining style of speaking; a kind of mournful or artificial strain of voice; an affected speaking with a measured rhythm ahd a regular rise and fall of the voice; as, children often read with a tone.
(n.) A sound considered as to pitch; as, the seven tones of the octave; she has good high tones.
(n.) The larger kind of interval between contiguous sounds in the diatonic scale, the smaller being called a semitone as, a whole tone too flat; raise it a tone.
(n.) The peculiar quality of sound in any voice or instrument; as, a rich tone, a reedy tone.
(n.) A mode or tune or plain chant; as, the Gregorian tones.
(n.) That state of a body, or of any of its organs or parts, in which the animal functions are healthy and performed with due vigor.
(n.) Tonicity; as, arterial tone.
(n.) State of mind; temper; mood.
(n.) Tenor; character; spirit; drift; as, the tone of his remarks was commendatory.
(n.) General or prevailing character or style, as of morals, manners, or sentiment, in reference to a scale of high and low; as, a low tone of morals; a tone of elevated sentiment; a courtly tone of manners.
(n.) The general effect of a picture produced by the combination of light and shade, together with color in the case of a painting; -- commonly used in a favorable sense; as, this picture has tone.
(v. t.) To utter with an affected tone.
(v. t.) To give tone, or a particular tone, to; to tune. See Tune, v. t.
(v. t.) To bring, as a print, to a certain required shade of color, as by chemical treatment.
Example Sentences:
(1) The vascular endothelium is capable of regulating tissue perfusion by the release of endothelium-derived relaxing factor to modulate vasomotor tone of the resistance vasculature.
(2) In summary, GABAergic tone did not effect basal acid secretion in anesthetized rats.
(3) After midazolam infusion, there was a 50% decrease in amplitude of P3 in response to target tones (P less than 0.006), whereas N3 latency increased by 40 ms (P less than 0.05).
(4) All of this in the same tones of weary nonchalance you might use to stop the dog nosing around in the bin.
(5) More disturbing than his ideas was Malema's style and tone.
(6) Noradrenaline decreased the phasic contraction amplitude of the circular muscle and exerted a stimulant effect on the tone which suggested an existence of two alpha 1-adrenoceptor subtypes.
(7) Histamine (10(-6)-10(-4) M) induced concentration-dependent increases in tone and Ca2+i, but these responses were not sustained.
(8) Masking experiments are demonstrated for electrical frequency-modulated tone bursts from 1,000 to 10,000 cps and from 10,000 to 1,000 cps with superimposed clicks.
(9) The stimuli were two simple tones in experiment 1 and two tonal complexes in both experiments 2 and 3.
(10) Isolated outer hair cells from the organ of Corti of the guinea pig have been shown to change length in response to a mechanical stimulus in the form of a tone burst at a fixed frequency of 200 Hz (Canlon et al., 1988).
(11) Complex tones containing the first 20 harmonics of 50, 100, or 200 Hz, all at equal amplitude, were used.
(12) An attempt to eliminate the age effect by adjusting for age differences in monaural shadowing errors, fluid intelligence, and pure-tone hearing loss did not succeed.
(13) Inhibition of the production or action of these substances will allow for vasodilatation, and it is probable that perinatal pulmonary vascular tone reflects a balance between local prostaglandin and leukotriene production.
(14) Subject evaluations in accordance with the intensity levels of tones, i.e.
(15) Maximum expiratory flow on partial flow-volume curve at 25% forced vital capacity (PEF25) was measured as an index showing basal bronchomotor tone.
(16) Twenty-four hours later, a stimulus generalization test was conducted in the absence of drug; during this session, tones that varied in frequency around 4.5 KHz were presented while the animals were responding under the VI schedule.
(17) Auditory sensory perception was operationalized as number of tones heard on audiometric examination.
(18) Later, Lucas, also a former party leader, strongly defended Bennett, saying it was a “bad day for Natalie” but there was also “kind of a gloating tone that strikes one as having something to do with her being a woman in there too”.
(19) From a set of tones that varied only in intensity, it was possible to calculate the growth of loudness with intensity for the budgerigar.
(20) Two hundred forty-six fetuses had at least one abnormal biophysical profile variable with the risk of bad outcome, for a single abnormal variable, ranging from 8% (body movements) to 100% (tone) and increasing from 14% (any variable abnormal) to 63% (all variables abnormal).