(superl.) Large in space; of much size; big; immense; enormous; expanded; -- opposed to small and little; as, a great house, ship, farm, plain, distance, length.
(superl.) Large in number; numerous; as, a great company, multitude, series, etc.
(superl.) Long continued; lengthened in duration; prolonged in time; as, a great while; a great interval.
(superl.) Superior; admirable; commanding; -- applied to thoughts, actions, and feelings.
(superl.) Endowed with extraordinary powers; uncommonly gifted; able to accomplish vast results; strong; powerful; mighty; noble; as, a great hero, scholar, genius, philosopher, etc.
(superl.) Holding a chief position; elevated: lofty: eminent; distingushed; foremost; principal; as, great men; the great seal; the great marshal, etc.
(superl.) Entitled to earnest consideration; weighty; important; as, a great argument, truth, or principle.
(superl.) Pregnant; big (with young).
(superl.) More than ordinary in degree; very considerable in degree; as, to use great caution; to be in great pain.
(superl.) Older, younger, or more remote, by single generation; -- often used before grand to indicate one degree more remote in the direct line of descent; as, great-grandfather (a grandfather's or a grandmother's father), great-grandson, etc.
(n.) The whole; the gross; as, a contract to build a ship by the great.
Example Sentences:
(1) Arterial compliance of great vessels can be studied through the Doppler evaluation of pulsed wave velocity along the arterial tree.
(2) Both apertures were repaired with great caution using individual sutures without resection of the hernial sac.
(3) However, ticks, which failed to finish their feeding and represent a disproportionately great part of the whole parasite's population, die together with them and the parasitic system quickly restores its stability.
(4) To be fair to lads who find themselves just a bus ride from Auschwitz, a visit to the camp is now considered by many tourists to be a Holocaust "bucket list item", up there with the Anne Frank museum, where Justin Bieber recently delivered this compliment : "Anne was a great girl.
(5) Subtypes of HBs Ag are already of great use in the epidemiology of hepatitis B virus infections; yet they may have additional significance.
(6) Until the 1960's there was great confusion, both within and between countries, on the meaning of diagnostic terms such as emphysema, asthma, and chronic brochitis.
(7) For viewers in the US, you get the worst possible in-game managerial interview in Mike Matheny, one that's so bad, it's actually great!
(8) When compared with lissencephalic species, a great horizontal fibrillary system (which is vertically arranged in gyral regions) was observed in convoluted brains.
(9) DI James Faulkner of Great Manchester police said: “The men and women working in the factory have told us that they were subjected to physical and verbal assaults at the hands of their employers and forced to work more than 80-hours before ending up with around £25 for their week’s work.
(10) Nucleotide, which is essential for catalysis, greatly enhances the binding of IpOHA by the reductoisomerase, with NADPH (normally present during the enzyme's rearrangement step, i.e., conversion of a beta-keto acid into an alpha-keto acid, in either the forward or reverse physiological reactions) being more effective than NADP.
(11) Over the past decade the use of monoclonal antibodies has greatly advanced our knowledge of the biological properties and heterogeneity that exist within human tumours, and in particular in lung cancer.
(12) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(13) It’s great to observe the beach from that perspective.
(14) The dose response effect in this tumor is steep and combinations which compromise the dose of adriamycin too greatly are showing inferior results.
(15) Although the relative contributions of different fuels varies greatly in different organisms, in none is there a simple reliance on stored ATP.
(16) = 19) with a very low, but statistically significant, correlation with the AUC, r = 0.35 (p less than 0.05), thus demonstrating a very great individual variation in sensitivity to cimetidine.
(17) The popularly used procedure in Great Britain is that in which a sheet of Ivalon sponge is sutured to the sacrum and wrapped around the rectum thus anchoring it in place.
(18) Transfection of the treated DNA into SOS-induced spheroplasts results in an increase in mutagenesis as great as 50-fold.
(19) From the social economic point of view nosocomial infections represent a very important cost factor, which could be reduced to great deal by activities for prevention of nosocomial infection.
(20) We conclude that inflammatory lesions at these sites are not uncommon and that CT scans are diagnostic in the great majority.
Maximum
Definition:
(n.) The greatest quantity or value attainable in a given case; or, the greatest value attained by a quantity which first increases and then begins to decrease; the highest point or degree; -- opposed to minimum.
(a.) Greatest in quantity or highest in degree attainable or attained; as, a maximum consumption of fuel; maximum pressure; maximum heat.
Example Sentences:
(1) Combinations of maximum amounts of glucagon and the cyclic nucleotide did not produce a greater effect than either agent alone.
(2) Maximum increases in portal plasma secretin concentrations of 143, 146 and 190% and maximum increases in VIP of 116, 155 and 147% after, respectively, intraduodenal 0.1 M NaHCO3, 0.1 M Na2CO3, and 0.025 M NaOH were found.
(3) These effects are similar to those reported for AVP and phorbol esters, activators of protein kinase C. Forskolin and isoproterenol, which induce cAMP accumulation, activated extractable topoisomerase II (maximum 5-15 min after treatment), but not topoisomerase I. Permeable cyclic nucleotide analogs dBcAMP and 8BrcGMP selectively activated extractable topoisomerase II and topoisomerase I activities, respectively.
(4) After vascular injury, smooth muscle cells proliferate, reaching a maximum rate at day 2.
(5) The ED50 and ED95 of mivacurium in each group were estimated from linear regression plots of log dose vs probit of maximum percentage depression of neuromuscular function.
(6) Bipolar derivations with the maximum PSE always included the locations with the maximum PSE obtained from a linked ears reference.
(7) The maximum amplitude of the inward Na+ current, normalized by cell capacitance, is about sixfold larger, on the average, in LP lactotropes than in SP lactotropes.
(8) After several months, a temporal discrimination was well established, as shown by maximum suppression toward the end of the signal period.
(9) Because they generally have to be positioned on hills to get the maximum benefits of the wind, some complain that they ruin the landscape.
(10) These levels are sufficient to maintain normal in vivo rates of mRNA and rRNA synthesis, but the average density of packing of polymerases on DNA is considerably less than the maximum density predicted by Miller and Bakken (1972), suggesting that initiation of polymerases of DNA is a limiting factor in the control of transcription.
(11) The maximum duration of the drainage was 24 days and complete recovery was obtained in all patients without further surgical treatments.
(12) Treatment of all groups continued for a maximum of 104 wk.
(13) However, as all subjects had normal hearing and maximum speech discrimination scores pre-smoking, it can only be concluded that smoking marihuana did not worsen the hearing--the experiments were not designed to see whether it would improve hearing.
(14) The terms of maximum reduction of the enzymatic activity falling within the 4th-6th and 24th hours and 2nd day should be taken into account while developing the methods of metabolic protection and enzyme therapy of the ischaemic myocardium.
(15) Neuropeptides increased the labeling of p115 within seconds and with great potency; half-maximum concentrations were 0.1, 0.2 and 0.3 nM for bombesin, vasopressin, and VIC, respectively.
(16) At temperatures greater than 150 degrees C the mutagenic activity of the cooked meat increased to reach a maximum at 300 degrees C. In another series of experiments, lamb patties were cooked at 250 degrees C for 2, 4, 6, 8, 10 and 12 min.
(17) It was shown that the levels of ATP and ADP in the mycelium depended on the carbon source: the maximum and minimum ATP concentrations were found on the glucose and acetate media respectively, the maximum and minimum ADP concentrations showed inverse dependence.
(18) Typical kinetics of local anaesthetics are presented for various methods of regional anaesthesia informing the anaesthetist on corresponding plasma concentrations if the recommended maximum doses are exceeded and thus he gets useful information for his daily work.
(19) Atrioventricular (AV) delay that results in maximum ventricular filling and physiological mechanisms that govern dependence of filling on timing of atrial systole were studied by combining computer experiments with experiments in the anesthetized dog instrumented to measure phasic mitral flow.
(20) The activity was maximum at the 16-32-cell stage and then decreased to a minimum at the mesenchyme blastula stage.