(superl.) Large in space; of much size; big; immense; enormous; expanded; -- opposed to small and little; as, a great house, ship, farm, plain, distance, length.
(superl.) Large in number; numerous; as, a great company, multitude, series, etc.
(superl.) Long continued; lengthened in duration; prolonged in time; as, a great while; a great interval.
(superl.) Superior; admirable; commanding; -- applied to thoughts, actions, and feelings.
(superl.) Endowed with extraordinary powers; uncommonly gifted; able to accomplish vast results; strong; powerful; mighty; noble; as, a great hero, scholar, genius, philosopher, etc.
(superl.) Holding a chief position; elevated: lofty: eminent; distingushed; foremost; principal; as, great men; the great seal; the great marshal, etc.
(superl.) Entitled to earnest consideration; weighty; important; as, a great argument, truth, or principle.
(superl.) Pregnant; big (with young).
(superl.) More than ordinary in degree; very considerable in degree; as, to use great caution; to be in great pain.
(superl.) Older, younger, or more remote, by single generation; -- often used before grand to indicate one degree more remote in the direct line of descent; as, great-grandfather (a grandfather's or a grandmother's father), great-grandson, etc.
(n.) The whole; the gross; as, a contract to build a ship by the great.
Example Sentences:
(1) Arterial compliance of great vessels can be studied through the Doppler evaluation of pulsed wave velocity along the arterial tree.
(2) Both apertures were repaired with great caution using individual sutures without resection of the hernial sac.
(3) However, ticks, which failed to finish their feeding and represent a disproportionately great part of the whole parasite's population, die together with them and the parasitic system quickly restores its stability.
(4) To be fair to lads who find themselves just a bus ride from Auschwitz, a visit to the camp is now considered by many tourists to be a Holocaust "bucket list item", up there with the Anne Frank museum, where Justin Bieber recently delivered this compliment : "Anne was a great girl.
(5) Subtypes of HBs Ag are already of great use in the epidemiology of hepatitis B virus infections; yet they may have additional significance.
(6) Until the 1960's there was great confusion, both within and between countries, on the meaning of diagnostic terms such as emphysema, asthma, and chronic brochitis.
(7) For viewers in the US, you get the worst possible in-game managerial interview in Mike Matheny, one that's so bad, it's actually great!
(8) When compared with lissencephalic species, a great horizontal fibrillary system (which is vertically arranged in gyral regions) was observed in convoluted brains.
(9) DI James Faulkner of Great Manchester police said: “The men and women working in the factory have told us that they were subjected to physical and verbal assaults at the hands of their employers and forced to work more than 80-hours before ending up with around £25 for their week’s work.
(10) Nucleotide, which is essential for catalysis, greatly enhances the binding of IpOHA by the reductoisomerase, with NADPH (normally present during the enzyme's rearrangement step, i.e., conversion of a beta-keto acid into an alpha-keto acid, in either the forward or reverse physiological reactions) being more effective than NADP.
(11) Over the past decade the use of monoclonal antibodies has greatly advanced our knowledge of the biological properties and heterogeneity that exist within human tumours, and in particular in lung cancer.
(12) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(13) It’s great to observe the beach from that perspective.
(14) The dose response effect in this tumor is steep and combinations which compromise the dose of adriamycin too greatly are showing inferior results.
(15) Although the relative contributions of different fuels varies greatly in different organisms, in none is there a simple reliance on stored ATP.
(16) = 19) with a very low, but statistically significant, correlation with the AUC, r = 0.35 (p less than 0.05), thus demonstrating a very great individual variation in sensitivity to cimetidine.
(17) The popularly used procedure in Great Britain is that in which a sheet of Ivalon sponge is sutured to the sacrum and wrapped around the rectum thus anchoring it in place.
(18) Transfection of the treated DNA into SOS-induced spheroplasts results in an increase in mutagenesis as great as 50-fold.
(19) From the social economic point of view nosocomial infections represent a very important cost factor, which could be reduced to great deal by activities for prevention of nosocomial infection.
(20) We conclude that inflammatory lesions at these sites are not uncommon and that CT scans are diagnostic in the great majority.
Muckle
Definition:
(a.) Much.
Example Sentences:
(1) Muckle-Wells syndrome is characterized by recurrent episodes of urticaria, fever, polyarthralgia, deafness and secondary amyloid (AA type), familial type with autosome dominant features; few cases have been described.
(2) This patient is likely to represent a variant of the Muckle-Wells syndrome (chronic relapsing urticaria, fever, arthralgia, deafness and renal amyloidosis).
(3) The Muckle and Well's syndrome corresponding to a transmission of the autosomic dominant type, combines bouts of urticaria, episodes of arthralgias to a shrinking of the ear and a sensory deafness.
(4) A case of hereditary AA amyloidosis with Muckle-Wells syndrome is described.
(5) The triad of renal amyloidosis, inner-ear deafness and recurrent urticaria is characteristic of Muckle-Wells syndrome, which has a hereditary basis.
(6) Like a rich country fruit cake, Kidnapped is seasoned throughout with handfuls of dialect words, "ain" (one), "bairn" (child), "blae" (cheerless), "chield" (fellow), "drammach" (raw oatmeal), "fash" (bother), "muckle" (big), "siller" (money), "unco" (extremely) , "wheesht!"
(7) Typical of the syndrome described by Muckle and Wells is a combination of progressive perceptive deafness appearing at various ages in a family, but usually at the same age in the same family, arthralgia, urticarious eruption and renal amyloidosis.
(8) At a consultation with a 31-year-old man, motivated by painful episodes of joint pain that had started considerably earlier, a familial disease entity was discovered that included the three clinical signs of the Muckle and Wells syndrome : urticarial eruption, intermittent pain in the limbs originating in the joints, and bilateral deafness of perception.
(9) It was presumably a complication of long-term immunosuppression and not of the Muckle-Wells syndrome.