(superl.) Large in space; of much size; big; immense; enormous; expanded; -- opposed to small and little; as, a great house, ship, farm, plain, distance, length.
(superl.) Large in number; numerous; as, a great company, multitude, series, etc.
(superl.) Long continued; lengthened in duration; prolonged in time; as, a great while; a great interval.
(superl.) Superior; admirable; commanding; -- applied to thoughts, actions, and feelings.
(superl.) Endowed with extraordinary powers; uncommonly gifted; able to accomplish vast results; strong; powerful; mighty; noble; as, a great hero, scholar, genius, philosopher, etc.
(superl.) Holding a chief position; elevated: lofty: eminent; distingushed; foremost; principal; as, great men; the great seal; the great marshal, etc.
(superl.) Entitled to earnest consideration; weighty; important; as, a great argument, truth, or principle.
(superl.) Pregnant; big (with young).
(superl.) More than ordinary in degree; very considerable in degree; as, to use great caution; to be in great pain.
(superl.) Older, younger, or more remote, by single generation; -- often used before grand to indicate one degree more remote in the direct line of descent; as, great-grandfather (a grandfather's or a grandmother's father), great-grandson, etc.
(n.) The whole; the gross; as, a contract to build a ship by the great.
Example Sentences:
(1) Arterial compliance of great vessels can be studied through the Doppler evaluation of pulsed wave velocity along the arterial tree.
(2) Both apertures were repaired with great caution using individual sutures without resection of the hernial sac.
(3) However, ticks, which failed to finish their feeding and represent a disproportionately great part of the whole parasite's population, die together with them and the parasitic system quickly restores its stability.
(4) To be fair to lads who find themselves just a bus ride from Auschwitz, a visit to the camp is now considered by many tourists to be a Holocaust "bucket list item", up there with the Anne Frank museum, where Justin Bieber recently delivered this compliment : "Anne was a great girl.
(5) Subtypes of HBs Ag are already of great use in the epidemiology of hepatitis B virus infections; yet they may have additional significance.
(6) Until the 1960's there was great confusion, both within and between countries, on the meaning of diagnostic terms such as emphysema, asthma, and chronic brochitis.
(7) For viewers in the US, you get the worst possible in-game managerial interview in Mike Matheny, one that's so bad, it's actually great!
(8) When compared with lissencephalic species, a great horizontal fibrillary system (which is vertically arranged in gyral regions) was observed in convoluted brains.
(9) DI James Faulkner of Great Manchester police said: “The men and women working in the factory have told us that they were subjected to physical and verbal assaults at the hands of their employers and forced to work more than 80-hours before ending up with around £25 for their week’s work.
(10) Nucleotide, which is essential for catalysis, greatly enhances the binding of IpOHA by the reductoisomerase, with NADPH (normally present during the enzyme's rearrangement step, i.e., conversion of a beta-keto acid into an alpha-keto acid, in either the forward or reverse physiological reactions) being more effective than NADP.
(11) Over the past decade the use of monoclonal antibodies has greatly advanced our knowledge of the biological properties and heterogeneity that exist within human tumours, and in particular in lung cancer.
(12) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(13) It’s great to observe the beach from that perspective.
(14) The dose response effect in this tumor is steep and combinations which compromise the dose of adriamycin too greatly are showing inferior results.
(15) Although the relative contributions of different fuels varies greatly in different organisms, in none is there a simple reliance on stored ATP.
(16) = 19) with a very low, but statistically significant, correlation with the AUC, r = 0.35 (p less than 0.05), thus demonstrating a very great individual variation in sensitivity to cimetidine.
(17) The popularly used procedure in Great Britain is that in which a sheet of Ivalon sponge is sutured to the sacrum and wrapped around the rectum thus anchoring it in place.
(18) Transfection of the treated DNA into SOS-induced spheroplasts results in an increase in mutagenesis as great as 50-fold.
(19) From the social economic point of view nosocomial infections represent a very important cost factor, which could be reduced to great deal by activities for prevention of nosocomial infection.
(20) We conclude that inflammatory lesions at these sites are not uncommon and that CT scans are diagnostic in the great majority.
Overwhelming
Definition:
(p. pr. & vb. n.) of Overwhelm
(a.) Overpowering; irresistible.
Example Sentences:
(1) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(2) She added: “We will continue to act upon the overwhelming majority view of our shareholders.” The vote was the second year running Ryanair had suffered a rebellion on pay.
(3) T cells admixed in the germinal centers were overwhelmingly of the T-helper type.
(4) Unfortunately for the governor, he could win both states and still face the overwhelming likelihood of failure if he doesn't take Ohio, where the poll found Obama out front 51-43.
(5) In Britain, the European election is overwhelmingly seen through the prism of domestic politics.
(6) Photograph: Christopher Thomond for the Guardian Asked if Watson should seek to refresh his mandate after Corbyn’s overwhelming victory among members, McCluskey added: “Well, if Tom wants to try to refresh his mandate it would be interesting to see what happens.” Watson said it was time “to be proud of our party”, because the Conservatives were beatable and the prime minister, Theresa May, could call an election any time.
(7) The government acknowledged it had been overwhelmed by the devastation from the deadliest quake in Nepal in over 80 years.
(8) He made me laugh and cry, and his courage in writing about what he was going through was sometimes quite overwhelming.
(9) Although alpha 1-antiprotease (alpha 1-AP) binds and inactivates NE and is the major antielastase of the lower respiratory tract, antielastase defenses may be overwhelmed in CF, leading to progressive lung damage.
(10) And HAP has shown that the key finding that debt slows growth was driven overwhelmingly by the exclusion of four years of data from New Zealand.
(11) Cathepsin D-like acid proteinase existed overwhelmingly in the mucosal layer and was hardly detected in the gastric juice.
(12) Hence, reaction of chemical carcinogen with nuclear DNA is possible only when the cell is overwhelmed leading to cell death, or following a temporary breach of the nuclear membrane control points, but the DNA damage in the latter is totally reparable.
(13) The facts are clear: the overwhelming majority of EU citizens in Britain are contributors, not freeloaders.” But that was not the official position of any of the parties involved, so it went mostly unsaid.
(14) Of 54 patients with poor-grade aneurysms, ventriculostomy was placed in 47 (87.0%) and yielded high ICP's in the overwhelming majority, with the mean ICP being 40.2 cm H2O.
(15) There is overwhelming evidence, today, that such factors are involved in the manifestation of acute as well as chronic, non-specific as well as well as specific inflammation.
(16) Mobile phone networks, overwhelmed by demand, were down for hours, with authorities advising people to use email or text messages instead.
(17) The immunity was enacted by an overwhelming bipartisan vote, with the support of leading Democrats including Barack Obama, who had promised - when seeking his party's nomination - to filibuster any bill that contained retroactive telecom immunity.
(18) There’s an overwhelming sadness among kids like that who have been kept there for a very long time.
(19) Panic attacks would overwhelm her periodically and she experienced regular “ scanxiety ” – the feelings of dread that grip patients before new tests.
(20) In the meantime, Malaysia Airlines’ overwhelming focus will be the same as it has been from the outset – to provide the families with a comprehensive support programme.