(superl.) Large in space; of much size; big; immense; enormous; expanded; -- opposed to small and little; as, a great house, ship, farm, plain, distance, length.
(superl.) Large in number; numerous; as, a great company, multitude, series, etc.
(superl.) Long continued; lengthened in duration; prolonged in time; as, a great while; a great interval.
(superl.) Superior; admirable; commanding; -- applied to thoughts, actions, and feelings.
(superl.) Endowed with extraordinary powers; uncommonly gifted; able to accomplish vast results; strong; powerful; mighty; noble; as, a great hero, scholar, genius, philosopher, etc.
(superl.) Holding a chief position; elevated: lofty: eminent; distingushed; foremost; principal; as, great men; the great seal; the great marshal, etc.
(superl.) Entitled to earnest consideration; weighty; important; as, a great argument, truth, or principle.
(superl.) Pregnant; big (with young).
(superl.) More than ordinary in degree; very considerable in degree; as, to use great caution; to be in great pain.
(superl.) Older, younger, or more remote, by single generation; -- often used before grand to indicate one degree more remote in the direct line of descent; as, great-grandfather (a grandfather's or a grandmother's father), great-grandson, etc.
(n.) The whole; the gross; as, a contract to build a ship by the great.
Example Sentences:
(1) Arterial compliance of great vessels can be studied through the Doppler evaluation of pulsed wave velocity along the arterial tree.
(2) Both apertures were repaired with great caution using individual sutures without resection of the hernial sac.
(3) However, ticks, which failed to finish their feeding and represent a disproportionately great part of the whole parasite's population, die together with them and the parasitic system quickly restores its stability.
(4) To be fair to lads who find themselves just a bus ride from Auschwitz, a visit to the camp is now considered by many tourists to be a Holocaust "bucket list item", up there with the Anne Frank museum, where Justin Bieber recently delivered this compliment : "Anne was a great girl.
(5) Subtypes of HBs Ag are already of great use in the epidemiology of hepatitis B virus infections; yet they may have additional significance.
(6) Until the 1960's there was great confusion, both within and between countries, on the meaning of diagnostic terms such as emphysema, asthma, and chronic brochitis.
(7) For viewers in the US, you get the worst possible in-game managerial interview in Mike Matheny, one that's so bad, it's actually great!
(8) When compared with lissencephalic species, a great horizontal fibrillary system (which is vertically arranged in gyral regions) was observed in convoluted brains.
(9) DI James Faulkner of Great Manchester police said: “The men and women working in the factory have told us that they were subjected to physical and verbal assaults at the hands of their employers and forced to work more than 80-hours before ending up with around £25 for their week’s work.
(10) Nucleotide, which is essential for catalysis, greatly enhances the binding of IpOHA by the reductoisomerase, with NADPH (normally present during the enzyme's rearrangement step, i.e., conversion of a beta-keto acid into an alpha-keto acid, in either the forward or reverse physiological reactions) being more effective than NADP.
(11) Over the past decade the use of monoclonal antibodies has greatly advanced our knowledge of the biological properties and heterogeneity that exist within human tumours, and in particular in lung cancer.
(12) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(13) It’s great to observe the beach from that perspective.
(14) The dose response effect in this tumor is steep and combinations which compromise the dose of adriamycin too greatly are showing inferior results.
(15) Although the relative contributions of different fuels varies greatly in different organisms, in none is there a simple reliance on stored ATP.
(16) = 19) with a very low, but statistically significant, correlation with the AUC, r = 0.35 (p less than 0.05), thus demonstrating a very great individual variation in sensitivity to cimetidine.
(17) The popularly used procedure in Great Britain is that in which a sheet of Ivalon sponge is sutured to the sacrum and wrapped around the rectum thus anchoring it in place.
(18) Transfection of the treated DNA into SOS-induced spheroplasts results in an increase in mutagenesis as great as 50-fold.
(19) From the social economic point of view nosocomial infections represent a very important cost factor, which could be reduced to great deal by activities for prevention of nosocomial infection.
(20) We conclude that inflammatory lesions at these sites are not uncommon and that CT scans are diagnostic in the great majority.
Utmost
Definition:
(a.) Situated at the farthest point or extremity; farthest out; most distant; extreme; as, the utmost limits of the land; the utmost extent of human knowledge.
(a.) Being in the greatest or highest degree, quantity, number, or the like; greatest; as, the utmost assiduity; the utmost harmony; the utmost misery or happiness.
(n.) The most that can be; the farthest limit; the greatest power, degree, or effort; as, he has done his utmost; try your utmost.
Example Sentences:
(1) Differentiation between these two types of lesions is of utmost importance since the surgical approach will be different.
(2) In order to achieve guineaworm eradication in 1990s, the Guineaworm Eradication Programme (GWEP) should operate with utmost efficiency; and needs to be concurrently evaluated for timely corrective measures.
(3) The pH of the extraction buffer was of the utmost importance, since it was demonstrated that a pH greater than 5 would give rise to false signals.
(4) Whereas live Toxoplasma "vaccines" may be effective in sheep and goats, the eventual preparation of a killed vaccine capable of inducing long-term protection is of the utmost importance.
(5) Despite advantages and technological advances in the techniques of dental casts and ceramics attachment to metal, plastic materials for crown and bridge facetting are still of utmost importance for prosthetic procedures.
(6) * * * Stalker, meanwhile, having made his decision, pursued Tape 042 with the utmost vigour.
(7) Early recognition of the major peroxisomal disorders in which functional peroxisomes are virtually absent, leading to a generalised impairment of peroxisomal functions, is of utmost importance, as this will enable the prenatal diagnosis of these severe diseases in future pregnancies.
(8) It is incumbent on the US, Britain and France to do their utmost to help the country win the peace.
(9) We conclude that the stimulation of Pk-C is of utmost importance for OL regeneration.
(10) However, it is of utmost importance that the institutes in "Eastern Europe" establish these standards as soon as possible in order to be competitive and to be able to join research-projects with "Western" universities - a necessary source of income.
(11) A consultant knowledgeable in the problems of the spinal cord injured can be of utmost benefit especially in the labor and delivery process.
(12) Intubation, artificial ventilation, fluid administration (electrolyte-solution) are of utmost importance for their survival and to reduce the frequency of major complications.
(13) As such, we treat any such allegations with the utmost seriousness and we will be contacting Jess to offer to discuss her concerns in full.” Sutton, in his own statement, said: “I wholeheartedly deny that I said or did anything other than act with complete professionalism in my dealings with Jess.
(14) Incidence of renal hydatid cyst is rare and its diagnosis should be made with the utmost care and after subjecting the patient to intensive investigations to exclude other pathologies.
(15) Both numbering systems initiate at the utmost 5' terminus of mRNA synthesis; this 5' initiator nucleotide is assigned 1.
(16) He fulfilled a difficult role in a progressive and compassionate way … he has done his utmost to transform the CPS's record on rape and domestic violence, delivering improved conviction rates for both.
(17) This is of the utmost importance, both epidemiologically and from the individual patient's point of view, and is a prerequisite in preventing the spread of HIV infection.
(18) This may be partly due to excessive patient fear according to the general belief that the heart is the utmost important part of life.
(19) Vaginal scanning of the ovaries and the uterus is a diagnostic and monitoring tool of utmost importance in assisted conception.
(20) In severe cases where hemorrhages play so large a role, albeit infrequently, the specific action of iron in interference with coagulation mechanisms is of the utmost importance.