(1) In order to determine the division at which chromosome loss occurs, we estimated the fraction of XO nuclei resulting from X chromosome loss by scoring the phenotype of 47 adult cuticular landmarks in 160 XX-XO mosaics (gynandromorphs) derived from maternal X chromosome loss, and 33 gynandromorphs derived from paternal X chromosome loss.
(2) The defects observed in the gynandromorphs demonstrate widespread requirements for PS integrins during development especially in ventrally derived structures, which also show strong expression of PS beta integrin.
(3) Regeneration was induced either by cutting the disc in situ, or by shifting gynandromorphic larvae whose male tissue was hemizygous for a temperature-sensitive cell lethal to the restrictive temperature.
(4) The sex appeal of 287 gynandromorphs was examined in order to localize the sex appeal focus by means of blastoderm fate mapping.
(5) Similar fate maps are obtained using data from gynandromorphs and from marked Y chromosome (nonsexually dimorphic) mosaics.
(6) A neurophysiological study of a behavioral phenotype caused by a sex-linked single gene mutation has been performed with gynandromorphs, mosaic for the mutant gene, Hyperkinetic(1P) (Hk(1P)), in Drosophila melanogaster.
(7) A pair of male monozygous twins of gynandromorphic habitus but normal male body hair and genitalia, who appear concordant for transsexualism and explosive personality disorder but discordant for schizophrenia, is presented.
(8) The occurrence of gynandromorphs indicates that the mutant probably interferes with the processes of X-chromosome elimination.
(9) The regions affected by these lethals were identified more precisely by analysis of the tissue distributions in the surviving gynandromorphs.
(10) First, with gynandromorphs, we removed the wild-type gene long before the critical developmental events to produce large mutant clones.
(11) Next, we observed the courtship behaviors that gynandromorphs (sex mosaics) performed in response to attractive males and females.
(12) The mutant is recessive and maternal in action, producing gynandromorphs and haplo-4 mosaics among the progeny of homozygous mit females.
(13) A developmental analysis of gynandromorphic genetic mosaics shows that: (1) the gene function is autonomously essential in the eye; (2) the gene function is essential for normal development of the optic lobes; and (3) the gene function is not necessary in most major imaginal-disc cell derivatives with the exception of the eye disc.
(14) The gene claret nondisjunctional was used for the production of gynandromorphs which showed that the enhancing ability of z(a), like the eye pigment change caused by z, is autonomous.
(15) We show here that gynandromorphic females respond to pheromonal stimulation with anemotaxis.
(16) Only one was reported to be a gynandromorph; sex ratios generally have been near 1 : 1.
(17) The male tissue of this gynandromorph is hemizygous for Hk(1P), while the female tissue is heterozygous.
(18) Some interneurones in the antennal lobes of female moths that have received grafts of male antennae (gynandromorphs) respond postsynaptically to stimulation with bombykal, a major component of the pheromone.
(19) Using gynandromorph the fate map of Drosophila melanogaster blastoderm was constructed.
(20) Twenty adult cuticular structures of 1211 haploid-diploid gynandromorphs were placed on the fate map using the sturtoid calculation.
Intersex
Definition:
Example Sentences:
(1) A reciprocal translocation, identified as t(6p+; 14q-), is described in a 38,XX intersex pig.
(2) Moreover, the presence of a loss-of-function runt mutation masculinizes triploid intersexes.
(3) Before 1975, the management of intersex was associated with a later age at diagnosis and initial operation, and a higher incidence of multistaged procedures performed by multiple surgeons from different specialties.
(4) There was no acknowledgement in the agreement of the “deep pain these decisions will cause, nor any concern for the pastoral care of [lesbian, gay, bisexual, transexual and intersex] Christians,” she said.
(5) Multiple genetic, molecular, and transformation experiments show that female-specific activation of genes or gene products occurs in the order Sex lethal greater than transformer greater than transformer-2 greater than doublesex greater than or equal to intersex greater than female differentiation.
(6) Hence, RNA synthesis in vitro was unspecific and did not reflect the in vivo RNA synthesis.--On the other hand, E.coli RNA polymerase completely mimics in vitro the dosage compensation phenomenon making twice as much RNA on one X-chromosome of males (1X2A) as on each of X-chromosomes of diploid (2X2A) and triploid (3X3A) females and super-females (3X2A), and the intermediate amount of RNA on each of X-chromosomes of intersexes (2X3A).
(7) Triploid intersexes homozygous for a mutant (msl-2) known to impede the hyperactivation of the X chromosome in diploid males differentiate into adults, sexually indistinguishable from their heterozygous sibs.
(8) Data on gross morphology, histology of the genitalia, and genetic sex using blood, skin and gonads were employed for the classification of the type of intersex in each case.
(9) To do this, we monitored the sexual behaviors of flies with mutations in the transformer (tra), doublesex (dsx) and intersex (ix) genes.
(10) This unexpected result is rationalized in terms of differential lethality of individuals at the two extremities of the distribution of X-activity levels in intersexes raised at a particular temperature.
(11) Genetic and molecular tests with this ectopically expressed gene are consistent with the following order of gene action: X chromosome to autosome ratio----Sex lethal----transformer----transformer-2----doublesex----intersex--- - terminal differentiation.
(12) An enzyme-linked immunoassay (ELISA) for AMH was used to investigate three intersex infants.
(13) An increased risk of harbouring CIS has been reported in men with a history of cryptorchidism, in contralateral testes of men previously treated for unilateral germ cell tumour, in intersex patients, in men with assumed extragonadal germ cell tumour and possibly in infertile men.
(14) In this article the intersex disorders are discussed, with particular emphasis on the chromosomal and endocrine investigations.
(15) "We now hope that this step forward translates into real improvements in the lives of lesbian, gay, bisexual, transgender and intersex people in Uganda, who have been trapped in a vicious circle of discrimination, threats, abuse and injustice for too long."
(16) Recognition of the intersex goat, which may have a masculine, feminine, or intermediate phenotype, is necessary in herds where naturally polled animals are bred.
(17) Recently, however, some Muniri, Dunkwi and northern Simbari hamlets recognize these individuals as male in infancy and rear them as boys, calling them 'kwalatmala' to distinguish them from normal males, accepting them as an intersex destined to occupy male adult roles.
(18) In a liberal democracy – one that values equality before the law – public institutions should not be able to discriminate on the basis of sexual orientation, gender identity or intersex status.
(19) Other cases of equine intersexes are reviewed and theories for the discrepancies between genetic, gonadal and phenotypic sex are discussed.
(20) Intersex states are rare but if unsuspected may cause diagnostic confusion.