What's the difference between haematin and haematoin?
Haematin
Definition:
(n.) Same as Hematin.
Example Sentences:
(1) It is postulated that the linkage between the haem groups of dimeric haem and the haematin groups of dimeric haematin is essentially hydrophobic in nature.
(2) Typically, haem therapy has been given in the form of haematin--haem dissolved in alkali.
(3) Metmyoglobin was only partially re-formed by adding haematin to the precipitate produced by apomyoglobin with an antiserum of the first group, whereas complete re-formation of metmyoglobin was achieved in the presence of antisera of the second group.
(4) Haematins (hydroxyferriprotoporphyrin IX) constitute a possible receptor for antimalarial drugs such as chloroquine or quinine.
(5) The use of erythrocyte morphology as a screening test for deficient absorption of haematinics is unsatisfactory; false positive (42.8%) and false negative (41.6%) results are encountered too frequently to recommend its use.
(6) A recently published method for measuring human haemoglobin based on alkaline haematin (Zander et al., Clin.
(7) Actinomycin D, puromycin or cycloheximide prevent the activation of the enzyme by 5-aminolaevulinate but not that by haematin.
(8) The deficiency of haematinic factors appears to be largely due to poor nutrition.
(9) None of the patients received haematinics during the study period.
(10) Some other phenol compounds (caffeic acid and 4-hydroxy-3-methoxybenzoic acid) also showed inhibitory effects on the haematin- and haemoglobin-catalysed epoxidation, but salicylic acid did not.
(11) The antiporphyrogenic effect of haem arginate (even after storage for two years) in 2-allyl-2-isopropylacetamide-induced experimental porphyria of rats was equal to that of freshly prepared haematin.
(12) The distressing misdiagnosis of the cause of this anaemia is pointed out, and the consequent misuse of haematinics in the form of blood transfusion, iron and vitamin B12 is shown.
(13) The major GSH transferase was inhibited by haematin-related compounds, bile acids and a number of anthelmintics including members of the benzimidazole and phenol-based class of compounds.
(14) In females the digestion of white mice blood to haematin at 23-24 degrees lasted not over 12 hours, the digestion of blood of hamsters and man - 12 to 20 hours, of guinea pigs and reptiles - 18 to 25 hours and of white rats and pigeons - from 20 to 30 hours.
(15) The findings are discussed in relation to replacement of bone marrow by lepromatous tissue as well as possible interference in the metabolism of haematinics by M. leprae.
(16) Supplementation of haematinic therapy with these compounds is recommended.
(17) The combined injection of either haematin or 5-aminolaevulinate with cortisol does not produce an additive effect, whereas potentation is observed when tryptophan is jointly given with either the cofactor or the haem precursor.
(18) Thereafter, endosomes decreased in size as digestion proceeded and there was an increase of haematin granules.
(19) Three interrelated parenchymal perikaryal pigments were identified in the putaminal lesions of all 3 patients: a "haematin" pigment, neuromelanin and lipofuscin.
(20) During pregnancy, the women received a haematinic supplement of 500 micrograms pteroyl glutamic acid and 47 mg iron a day, and a food supplement was also given to some of the women during either pregnancy, or lactation, or both.
Haematoin
Definition:
(n.) A substance formed from the hematin of blood, by removal of the iron through the action of concentrated sulphuric acid. Two like bodies, called respectively haematoporphyrin and haematolin, are formed in a similar manner.