(n.) An electro-negative element or radical, which, by combination with a metal, forms a haloid salt; especially, chlorine, bromine, and iodine; sometimes, also, fluorine and cyanogen. See Chlorine family, under Chlorine.
Example Sentences:
(1) 5-Bromo-5'-amino-2',5'-dideoxyuridine (11, ABrU) and 5-iodo-5'-amino-2',5'-dideoxyuridine (12, AIU) were prepared by halogenation of the 5-mercuriacetate of 5'-amino-2',5'-dideoxyuridine.
(2) Such disturbances may be induced by opiates, benzodiazepines, phenothiazines, butyrophenones, ketamine, etomidate, propofol, nitrous oxide, and halogenated inhalation anesthetics as well as by H2-blocking agents such as cimetidine.
(3) It is concluded that both halogenated and natural purine ribonucleotides interact in a similar manner with the enzyme molecule.
(4) The flumazenil analogue, Ro 16-0154, a benzodiazepine partial inverse agonist, has been labeled by halogen exchange to enable SPECT investigations of central benzodiazepine receptors in the human brain.
(5) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(6) Annual savings in tonnes of CO 2 Install 2 kilowatt solar PV panels 0.4 Buy a new A++ refrigerator if yours is more than 4 years old, and only use a small-screen TV 0.1 Use LED or fluorescent lights where you currently have halogen lights installed 0.1 Buy an automated system to turn off appliances when not in use; get a meter that shows actual energy use and use it to monitor your household 0.1 Only use your washing machine and dishwasher when full to capacity and at lowest temperature 0.1 Never use the tumble dryer 0.1 Get rid of the freezer if you can, and replace your small appliances with "eco" varieties 0.1 Car (1.5 tonnes of CO 2 ) There is one car for every two people in the UK, and each one travels an average of about 9,000 miles a year.
(7) We have studied the time-resolved and the steady-state fluorescence of the DNA groove binders 4',6-diamidino-2-phenylindole (DAPI) and Hoechst 33258 with the double stranded DNAs poly(dA-dU) and poly(dI-dC) and their halogenated analogs, poly(dA-I5dU) and poly(dI-Br5dC).
(8) Halogenated anthelmintics were not metabolized to GSH conjugates in the helminths studied and did not inhibit GSH-S-aryltransferase activity towards chlorodinitrobenzene.
(9) Replacement of the 6-Cl group of amiloride by other halogen atoms had only modest effects on drug efficacy.
(10) This cannot be explained by metabolic activation of the halogenated hydrocarbons but could be due to a noxious effect on the mitotoc spindle.
(11) These observations indicate that Compound X is the halogenating intermediate in the chlorite reaction and that the rate of enzymatic chlorination is directly related to the stability of Compound X.
(12) As radiation sources, the following ones have proved useful: high-pressure mercury-vapour lamps, compound radiation systems consisting of high-pressure mercury-vapour burner, series coiled filament and reflector bulbs made of special glass as well as halogen metal-vapour lamps.
(13) This result suggests that a benefit may be expected in the clinic from the combined application of halogenated pyrimidines with repair inhibitors, if administered at a carefully screened range of concentrations.
(14) GC detection was carried out with a Coulson conductivity detector in the halogen (reductive) mode.
(15) Glutaraldehyde might inhibit Cl- transport in the TAL by cross-linking amino acid residues of the proteins essential for halogen transport across this segment.
(16) Treatment was administered with white light produced by a commercially available halogen-tungsten lamp.
(17) Various organic substances, which were measured by different indices such as total trihalomethanes (THM), total organic halogen (TOX) and the absorbence at 260 nm, could be recovered by this method much more efficiently and conveniently than by conventional methods.
(18) These results indicate that B cell mitogens act to release virus by a mechanism that differs from that of halogenated pyrimidines.
(19) Stability of halogenated volatile anesthetic is important because of the potential toxicity associated with the breakdown products.
(20) 111 chemicals of known rodent carcinogenicity (49 carcinogens, 62 noncarcinogens), including many promoters of carcinogenesis, nongenotoxic carcinogens, hepatocarcinogens, and halogenated hydrocarbons, were selected for study.
Iodine
Definition:
(n.) A nonmetallic element, of the halogen group, occurring always in combination, as in the iodides. When isolated it is in the form of dark gray metallic scales, resembling plumbago, soft but brittle, and emitting a chlorinelike odor. Symbol I. Atomic weight 126.5. If heated, iodine volatilizes in beautiful violet vapors.
Example Sentences:
(1) Conversely, Tyr-52 and Tyr-147 were iodinated only in the dimer.
(2) The results indicated that roughly 25% of patients treated in this way will become hypothyroid after 5 years and that 85% are cured (need no further therapy during the follow-up period) using a single dose of iodine-131.
(3) Subunits maintained under the above ionic conditions were compared with 30S and 50S particles at low (6 mM) magnesium concentration with respect to the reactivity of individual ribosomal proteins to lactoperoxidase-catalyzed iodination.
(4) In conclusion, autoimmune thyroiditis in an animal model can be prevented by reducing thyroidal iodine or its metabolism and optimal effects require intervention at the embryonic stage.
(5) CCK-8 was acylated with the iodinated aryl azide derivatives, methyl-3-azido-4-hydroxy-5-[125I]iodobenzimidate and N-[4-(4'-azido-3'-[125I]iodophenylazo)benzoyl]-3-aminopropionyl-N- oxy- succinimide.
(6) Labeling experiments with fucose and glucosamine show that at least nine of the iodinated peptides may be glycoproteins.
(7) The first one is a region with iodine insufficiency; the second one is a region where the people use table salt in excess.
(8) Superoxide dismutase (SOD) activity and its concentration were measured in thyroid tissues obtained from patients with Graves' disease, Hashimoto's thyroiditis, differentiated thyroid cancer, and endemic goiter (before and after iodine supplementation) as well as in normal thyroid tissue (paranodular tissue) from patients with follicular adenomas.
(9) A decrease in neutrophil oxidative metabolism and iodination was observed, but there was no effect on neutrophil random migration or ADCC.
(10) The preparation and utilization of iodinated glycopeptides for sequence analysis is presented.
(11) Two hundred fifty-one cervical and 209 male urethral specimens from three Richmond health clinics were read by direct immunofluorescence staining and compared with cell culture technics using iodine staining.
(12) In all iodine-deficient regions such as the GDR, a frequent occurrence of thyroid autonomy with manifestation of hyperthyroidism following iodine contamination has to be taken into account.
(13) After a resuscitation period of 4 h, the medium was made selective by addition of either sodium thiosulfate, bile salts and iodine, or sodium selenite and L-cystine.
(14) the does had been grazing on lucerne from the time of mating and received a free-choice lick, which included iodine.
(15) It was revealed that the TTH level could change both in the direction of decrease and of elevation; the inorganic phase of the iodine metabolism was reduced and the organic one--elevated.
(16) There was a significant inverse correlation between the TcTU values and the urinary iodine excretion in the groups of normal thyroids and of goitres with euthyroidism.
(17) Marked resistance to lung damage by toxic thioureas could be induced in older, mature rats by pretreatment with the toxic agent itself (tachyphylaxis), with other toxic and non-toxic antithyroid drugs or with iodine or iodide--even if the rats were pretreated at an early age before susceptibility to the agent developed.
(18) This study analyzed the impact of prognostic variables of age, sex, histopathological diagnosis, extent of disease at diagnosis, and surgical intervention on well differentiated thyroid carcinoma and how surgical treatment, radioactive iodine, and radiotherapy influence the patients' outcomes.
(19) All the iodinated proteins except the very prominently labeled high molecular weight protein (greater than 200,000 daltons) were located in a fraction identified enzymically and compositionally as plasma membrane.
(20) It has a number of advantages: it is far more rapid, less painful and offers good visualisation of the nerve roots as compared with air myelography; unlike myelography with iodine-based oils, it is not necessary to remove the contrast medium after the examination since Metrizamide is spontaneously resorbable.