What's the difference between handle and knob?

Handle


Definition:

  • (v. t.) To touch; to feel with the hand; to use or hold with the hand.
  • (v. t.) To manage in using, as a spade or a musket; to wield; often, to manage skillfully.
  • (v. t.) To accustom to the hand; to work upon, or take care of, with the hands.
  • (v. t.) To receive and transfer; to have pass through one's hands; hence, to buy and sell; as, a merchant handles a variety of goods, or a large stock.
  • (v. t.) To deal with; to make a business of.
  • (v. t.) To treat; to use, well or ill.
  • (v. t.) To manage; to control; to practice skill upon.
  • (v. t.) To use or manage in writing or speaking; to treat, as a theme, an argument, or an objection.
  • (v. i.) To use the hands.
  • (n.) That part of vessels, instruments, etc., which is held in the hand when used or moved, as the haft of a sword, the knob of a door, the bail of a kettle, etc.
  • (n.) That of which use is made; the instrument for effecting a purpose; a tool.

Example Sentences:

  • (1) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
  • (2) The most successful dyes were phenocyanin TC, gallein, fluorone black, alizarin cyanin BB and alizarin blue S. Celestin blue B with an iron mordant is quite successful if properly handled to prevent gelling of solutions.
  • (3) "The Samaras government has proved to be dangerous; it cannot continue handling the country's fate."
  • (4) Control of cell calcium handling and transport may be abnormal in hypertension.
  • (5) Equal numbers of handled and unhandled puparia were planted out at different densities (1, 2, 4 or 8 per linear metre) in fifty-one natural puparial sites in four major vegetation types.
  • (6) Arrogant, narcissistic, egotistical, brilliant – all of that I can handle in Paul,” Levinson writes.
  • (7) Isolated renal tubules and renal clearance techniques were used to characterize the renal handling of 2-deoxy-D-galactose (2-d-Gal) by the winter flounder (Pseudopleuronectes americanus).
  • (8) In this study, we examined renal tubular cell handling of digoxin and ouabain using LLC-PK1 cells, a model of proximal renal tubular cells.
  • (9) Just before Christmas the independent Kerslake report severely criticised Birmingham city council for its dysfunctional politics and, in particular, its handling of the so-called Trojan Horse affair, in which school governors were said to have set out to bring about an Islamic agenda into the curriculum contents and the day-to-day running of some schools.
  • (10) The effects of insulin on the renal handling of sodium, potassium, calcium, and phosphate were studied in man while maintaining the blood glucose concentration at the fasting level by negative feedback servocontrol of a variable glucose infusion.
  • (11) The Nd-Yag-Laser seems to be a useful device in transsphenoidal surgery due to its potent coagulation effect and comfortable handling.
  • (12) Techniques are described for the special handling of these cells as well as suitable assay procedures.
  • (13) The decision of the editors to solicit a review for the Medical Progress series of this journal devoted to current concepts of the renal handling of salt and water is sound in that this important topic in kidney physiology has recently been the object of a number of new, exciting and, in some instances, quite unexpected insights into the mechanisms governing sodium excretion.
  • (14) Possible reasons for the previous discrepancies between direct and isotopic methods are discussed, as are the effects of protein binding, sample handling, and storage conditions on oxalate values in plasma.
  • (15) In addition to working with hist colleagues on general review and health-policy matters, he also handled issues related to the special needs of children and helped to get third-party benefit packages altered to better suit the treatment needs of children.
  • (16) Furthermore, this system can be satisfactory handled by technical personnel after short periods of training.
  • (17) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
  • (18) Both techniques are used by industry and regulatory agencies to monitor levels of fungal contamination at various stages of food handling, storing, processing and marketing.
  • (19) The particular advantage of the method described here is the ease with which the supernatants can be collected and transferred to counting vials with minimal handling of radioactive samples.
  • (20) The greatest care should be exercised by industry in handling tremolite or materials contaminated with it.

Knob


Definition:

  • (n.) A hard protuberance; a hard swelling or rising; a bunch; a lump; as, a knob in the flesh, or on a bone.
  • (n.) A knoblike ornament or handle; as, the knob of a lock, door, or drawer.
  • (n.) A rounded hill or mountain; as, the Pilot Knob.
  • (n.) See Knop.
  • (v. i.) To grow into knobs or bunches; to become knobbed.

Example Sentences:

  • (1) The narrow intercellular ridge is smooth, whereas the epithelial cells have small cytoplasmic knobs between the cilia.
  • (2) The histochemical study of the LDH in the Trout embryo during the early organogenesis shows a specific localization in notochord cells, in mesodermic cells of the terminal knob and in some prosencephalic neuroblasts.
  • (3) Motor axons possessed elongate, irregularly shaped boutons en passant and morphologically variable boutons terminaux; the latter included huge endings with knobbed projectiles arising from thick collaterals, or smaller, round boutons from thin collaterals.
  • (4) Men might not have frills and furbelows as women traditionally do, but they’ve got spurious function: knobs on their watches or extra pockets on their jackets that are just as decorative as anything women wear.” 6.
  • (5) As with established cell lines, formation of zeiotic knobs at the isolated Type 1 cell surface appeared closely related to microfilamentous nets located beneath the plasmalemma.
  • (6) The isolated cells have an ovoid soma, a dendrite of variable length which terminates in a cilia-bearing knob and an axon, also of variable length.
  • (7) In addition, some reacted with either knob protrusions or caveolae of the host erythrocyte membrane; one reacted with a parasite-derived antigen present in the erythrocyte cytoplasm.
  • (8) "It might be that you think it's just a knob on the front panel, but maybe installing it requires you disassemble the front panel, and actually you need a mechanic to come and fit it," argues Rowley.
  • (9) wt from 80 to 95 kd in different knob-producing isolates of P. falciparum and is absent in knobless variants.
  • (10) To investigate environmental influences on the development of the olfactory epithelium, semi-thin sections were taken from the nasal septum of newborn and 30-day-old rabbits; the epithelial thickness and the number of olfactory knobs, supporting cells, dark basal cells, and receptor cells were compared.
  • (11) The spores of Rif-18 are pleomorphic and frequently exhibit terminal knobs.
  • (12) To investigate the involvement of actin filaments in concanavalin A (Con A)-induced cap formation and cytochalasin B (CB)-induced zeiotic knob migration, the distribution of F-actin was studied in Con A-treated and CB-treated Ehrlich ascites tumor cells (EATC) by fluorescence microscopy using heavy meromyosin conjugated with a fluorescent dye, N-(7-dimethylamino-4-methylcoumarinyl) maleimide, (DACM-HMM).
  • (13) 205 subjects each chose a "most pleasant" sound delivered through an earphone by turning the control knob on a continuously variable audio oscillator.
  • (14) Knobs which appear on the membrane of the infected erythrocytes adhere to the endothelium, causing the obstruction of cerebral microvessels.
  • (15) Cytoadherence of infected erythrocytes in vivo is associated with the presence of knobs on the erythrocyte surface, but we and others have shown recently that cytoadherence to C32 melanoma cells may occur in vitro in the absence of knobs.
  • (16) Systemic administration of the anti-inflammatory agent indomethacin blocked vascular leakage due to endothelial gap formation but had little or no effect on trophoblast knob penetration of vessels.
  • (17) After crossectomy which remains the most important stage, a short stripping is performed in an upward direction, substituting a packing for the olive shaped knob normally used.
  • (18) Under scanning electron microscopy, O. viverrini eggs looked like musk-melon skin; they had prominent shoulders and long knobs.
  • (19) Six culture-adapted knob-positive Plasmodium falciparum parasites, four of which were nonbinding in an in vitro cytoadherence assay, were tested for the presence of the knob-associated histidine-rich protein PfHRP1.
  • (20) Instead, there were free and spiral nerve terminals in the interstitium, and epilemmal knob-like or bouton-like endings surrounding non-encapsulated muscle fibers.