What's the difference between handle and lead?

Handle


Definition:

  • (v. t.) To touch; to feel with the hand; to use or hold with the hand.
  • (v. t.) To manage in using, as a spade or a musket; to wield; often, to manage skillfully.
  • (v. t.) To accustom to the hand; to work upon, or take care of, with the hands.
  • (v. t.) To receive and transfer; to have pass through one's hands; hence, to buy and sell; as, a merchant handles a variety of goods, or a large stock.
  • (v. t.) To deal with; to make a business of.
  • (v. t.) To treat; to use, well or ill.
  • (v. t.) To manage; to control; to practice skill upon.
  • (v. t.) To use or manage in writing or speaking; to treat, as a theme, an argument, or an objection.
  • (v. i.) To use the hands.
  • (n.) That part of vessels, instruments, etc., which is held in the hand when used or moved, as the haft of a sword, the knob of a door, the bail of a kettle, etc.
  • (n.) That of which use is made; the instrument for effecting a purpose; a tool.

Example Sentences:

  • (1) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
  • (2) The most successful dyes were phenocyanin TC, gallein, fluorone black, alizarin cyanin BB and alizarin blue S. Celestin blue B with an iron mordant is quite successful if properly handled to prevent gelling of solutions.
  • (3) "The Samaras government has proved to be dangerous; it cannot continue handling the country's fate."
  • (4) Control of cell calcium handling and transport may be abnormal in hypertension.
  • (5) Equal numbers of handled and unhandled puparia were planted out at different densities (1, 2, 4 or 8 per linear metre) in fifty-one natural puparial sites in four major vegetation types.
  • (6) Arrogant, narcissistic, egotistical, brilliant – all of that I can handle in Paul,” Levinson writes.
  • (7) Isolated renal tubules and renal clearance techniques were used to characterize the renal handling of 2-deoxy-D-galactose (2-d-Gal) by the winter flounder (Pseudopleuronectes americanus).
  • (8) In this study, we examined renal tubular cell handling of digoxin and ouabain using LLC-PK1 cells, a model of proximal renal tubular cells.
  • (9) Just before Christmas the independent Kerslake report severely criticised Birmingham city council for its dysfunctional politics and, in particular, its handling of the so-called Trojan Horse affair, in which school governors were said to have set out to bring about an Islamic agenda into the curriculum contents and the day-to-day running of some schools.
  • (10) The effects of insulin on the renal handling of sodium, potassium, calcium, and phosphate were studied in man while maintaining the blood glucose concentration at the fasting level by negative feedback servocontrol of a variable glucose infusion.
  • (11) The Nd-Yag-Laser seems to be a useful device in transsphenoidal surgery due to its potent coagulation effect and comfortable handling.
  • (12) Techniques are described for the special handling of these cells as well as suitable assay procedures.
  • (13) The decision of the editors to solicit a review for the Medical Progress series of this journal devoted to current concepts of the renal handling of salt and water is sound in that this important topic in kidney physiology has recently been the object of a number of new, exciting and, in some instances, quite unexpected insights into the mechanisms governing sodium excretion.
  • (14) Possible reasons for the previous discrepancies between direct and isotopic methods are discussed, as are the effects of protein binding, sample handling, and storage conditions on oxalate values in plasma.
  • (15) In addition to working with hist colleagues on general review and health-policy matters, he also handled issues related to the special needs of children and helped to get third-party benefit packages altered to better suit the treatment needs of children.
  • (16) Furthermore, this system can be satisfactory handled by technical personnel after short periods of training.
  • (17) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
  • (18) Both techniques are used by industry and regulatory agencies to monitor levels of fungal contamination at various stages of food handling, storing, processing and marketing.
  • (19) The particular advantage of the method described here is the ease with which the supernatants can be collected and transferred to counting vials with minimal handling of radioactive samples.
  • (20) The greatest care should be exercised by industry in handling tremolite or materials contaminated with it.

Lead


Definition:

  • (n.) An open way in an ice field.
  • (n.) A lode.
  • (n.) One of the elements, a heavy, pliable, inelastic metal, having a bright, bluish color, but easily tarnished. It is both malleable and ductile, though with little tenacity, and is used for tubes, sheets, bullets, etc. Its specific gravity is 11.37. It is easily fusible, forms alloys with other metals, and is an ingredient of solder and type metal. Atomic weight, 206.4. Symbol Pb (L. Plumbum). It is chiefly obtained from the mineral galena, lead sulphide.
  • (n.) An article made of lead or an alloy of lead
  • (n.) A plummet or mass of lead, used in sounding at sea.
  • (n.) A thin strip of type metal, used to separate lines of type in printing.
  • (n.) Sheets or plates of lead used as a covering for roofs; hence, pl., a roof covered with lead sheets or terne plates.
  • (n.) A small cylinder of black lead or plumbago, used in pencils.
  • (v. t.) To cover, fill, or affect with lead; as, continuous firing leads the grooves of a rifle.
  • (v. t.) To place leads between the lines of; as, to lead a page; leaded matter.
  • (v. t.) To guide or conduct with the hand, or by means of some physical contact connection; as, a father leads a child; a jockey leads a horse with a halter; a dog leads a blind man.
  • (v. t.) To guide or conduct in a certain course, or to a certain place or end, by making the way known; to show the way, esp. by going with or going in advance of. Hence, figuratively: To direct; to counsel; to instruct; as, to lead a traveler; to lead a pupil.
  • (v. t.) To conduct or direct with authority; to have direction or charge of; as, to lead an army, an exploring party, or a search; to lead a political party.
  • (v. t.) To go or to be in advance of; to precede; hence, to be foremost or chief among; as, the big sloop led the fleet of yachts; the Guards led the attack; Demosthenes leads the orators of all ages.
  • (v. t.) To draw or direct by influence, whether good or bad; to prevail on; to induce; to entice; to allure; as, to lead one to espouse a righteous cause.
  • (v. t.) To guide or conduct one's self in, through, or along (a certain course); hence, to proceed in the way of; to follow the path or course of; to pass; to spend. Also, to cause (one) to proceed or follow in (a certain course).
  • (v. t.) To begin a game, round, or trick, with; as, to lead trumps; the double five was led.
  • (v. i.) To guide or conduct, as by accompanying, going before, showing, influencing, directing with authority, etc.; to have precedence or preeminence; to be first or chief; -- used in most of the senses of lead, v. t.
  • (v. t.) To tend or reach in a certain direction, or to a certain place; as, the path leads to the mill; gambling leads to other vices.
  • (n.) The act of leading or conducting; guidance; direction; as, to take the lead; to be under the lead of another.
  • (n.) precedence; advance position; also, the measure of precedence; as, the white horse had the lead; a lead of a boat's length, or of half a second.
  • (n.) The act or right of playing first in a game or round; the card suit, or piece, so played; as, your partner has the lead.
  • (n.) The course of a rope from end to end.
  • (n.) The width of port opening which is uncovered by the valve, for the admission or release of steam, at the instant when the piston is at end of its stroke.
  • (n.) the distance of haul, as from a cutting to an embankment.
  • (n.) The action of a tooth, as a tooth of a wheel, in impelling another tooth or a pallet.

Example Sentences:

  • (1) Thirty-two patients (10 male, 22 female; age 37-82 years) undergoing maintenance haemodialysis or haemofiltration were studied by means of Holter device capable of simultaneously analysing rhythm and ST-changes in three leads.
  • (2) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
  • (3) LHRH therapy leads to higher plasma LH levels and a lower FSH in response to an intravenous LHRH test.
  • (4) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
  • (5) These are typically runaway processes in which global temperature rises lead to further releases of CO², which in turn brings about more global warming.
  • (6) Results indicated a .85 probability that Directive Guidance would be followed by Cooperation; a .67 probability that Permissiveness would lead to Noncooperation; and a .97 likelihood that Coerciveness would lead to either Noncooperation or Resistance.
  • (7) It would be fascinating to see if greater local government involvement in running the NHS in places such as Manchester leads over the longer term to a noticeable difference in the financial outlook.
  • (8) The Frenchman’s 65th-minute goal was a fifth for United and redemptive after he conceded the penalty from which CSKA Moscow took a first-half lead.
  • (9) Our results indicate that increasing the delay for more than 8 days following irradiation and TCD syngeneic BMT leads to a rapid loss of the ability to achieve alloengraftment by non-TCD allogeneic bone marrow.
  • (10) report the complications registered, in particular: lead's displacing 6.2%, run away 0.7%, marked hyperthermya 0.0%, haemorrage 0.4%, wound dehiscence 0.3%, asectic necrosis by decubitus 5%, septic necrosis 0.3%, perforation of the heart 0.2%, pulmonary embolism 0.1%.
  • (11) The availability and success of changes in reproductive technology should lead to a reappraisal of the indications for hysterectomy, especially in young women.
  • (12) Photoirradiation of F1 in the presence of the analog leads to inactivation depending linearly on the incorporation of label.
  • (13) In patients with coronary artery disease, electrocardiographic signs of left atrial enlargement (LAE-negative P wave deflection greater than or equal to 1 mm2 in lead V1) are associated with increased left ventricular end diastolic pressure (LVEDP).
  • (14) The new Somali government has enthusiastically embraced the new deal and created a taskforce, bringing together the government, lead donors (the US, UK, EU, Norway and Denmark), the World Bank and civil society.
  • (15) Suggested is a carefully prepared system of cycling videocassettes, to effect the dissemination of current medical information from leading medical centers to medical and paramedical people in the "bush".
  • (16) Mitonafide is the lead compound of a new series of antitumor drugs, the 3-Nitronaphthalimides, which have shown antineoplastic activity in vitro as well as in vivo.
  • (17) The presently available data allow us to draw the following conclusions: 1) G proteins play a mediatory role in the transmission of the signal(s) generated upon receptor occupancy that leads to the observed cytoskeletal changes.
  • (18) In the case presented, overdistension of a jejunostomy catheter balloon led to intestinal obstruction and pressure necrosis (of the small bowel), with subsequent abscess formation leading to death from septicemia.
  • (19) This is rapidly followed by a gamut of changes leading to demyelination.
  • (20) In crosses between inverted repeats, a single intrachromatid reciprocal exchange leads to inversion of the sequence between the crossover sites and recovery of both genes involved in the event.