What's the difference between handle and manipulate?

Handle


Definition:

  • (v. t.) To touch; to feel with the hand; to use or hold with the hand.
  • (v. t.) To manage in using, as a spade or a musket; to wield; often, to manage skillfully.
  • (v. t.) To accustom to the hand; to work upon, or take care of, with the hands.
  • (v. t.) To receive and transfer; to have pass through one's hands; hence, to buy and sell; as, a merchant handles a variety of goods, or a large stock.
  • (v. t.) To deal with; to make a business of.
  • (v. t.) To treat; to use, well or ill.
  • (v. t.) To manage; to control; to practice skill upon.
  • (v. t.) To use or manage in writing or speaking; to treat, as a theme, an argument, or an objection.
  • (v. i.) To use the hands.
  • (n.) That part of vessels, instruments, etc., which is held in the hand when used or moved, as the haft of a sword, the knob of a door, the bail of a kettle, etc.
  • (n.) That of which use is made; the instrument for effecting a purpose; a tool.

Example Sentences:

  • (1) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
  • (2) The most successful dyes were phenocyanin TC, gallein, fluorone black, alizarin cyanin BB and alizarin blue S. Celestin blue B with an iron mordant is quite successful if properly handled to prevent gelling of solutions.
  • (3) "The Samaras government has proved to be dangerous; it cannot continue handling the country's fate."
  • (4) Control of cell calcium handling and transport may be abnormal in hypertension.
  • (5) Equal numbers of handled and unhandled puparia were planted out at different densities (1, 2, 4 or 8 per linear metre) in fifty-one natural puparial sites in four major vegetation types.
  • (6) Arrogant, narcissistic, egotistical, brilliant – all of that I can handle in Paul,” Levinson writes.
  • (7) Isolated renal tubules and renal clearance techniques were used to characterize the renal handling of 2-deoxy-D-galactose (2-d-Gal) by the winter flounder (Pseudopleuronectes americanus).
  • (8) In this study, we examined renal tubular cell handling of digoxin and ouabain using LLC-PK1 cells, a model of proximal renal tubular cells.
  • (9) Just before Christmas the independent Kerslake report severely criticised Birmingham city council for its dysfunctional politics and, in particular, its handling of the so-called Trojan Horse affair, in which school governors were said to have set out to bring about an Islamic agenda into the curriculum contents and the day-to-day running of some schools.
  • (10) The effects of insulin on the renal handling of sodium, potassium, calcium, and phosphate were studied in man while maintaining the blood glucose concentration at the fasting level by negative feedback servocontrol of a variable glucose infusion.
  • (11) The Nd-Yag-Laser seems to be a useful device in transsphenoidal surgery due to its potent coagulation effect and comfortable handling.
  • (12) Techniques are described for the special handling of these cells as well as suitable assay procedures.
  • (13) The decision of the editors to solicit a review for the Medical Progress series of this journal devoted to current concepts of the renal handling of salt and water is sound in that this important topic in kidney physiology has recently been the object of a number of new, exciting and, in some instances, quite unexpected insights into the mechanisms governing sodium excretion.
  • (14) Possible reasons for the previous discrepancies between direct and isotopic methods are discussed, as are the effects of protein binding, sample handling, and storage conditions on oxalate values in plasma.
  • (15) In addition to working with hist colleagues on general review and health-policy matters, he also handled issues related to the special needs of children and helped to get third-party benefit packages altered to better suit the treatment needs of children.
  • (16) Furthermore, this system can be satisfactory handled by technical personnel after short periods of training.
  • (17) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
  • (18) Both techniques are used by industry and regulatory agencies to monitor levels of fungal contamination at various stages of food handling, storing, processing and marketing.
  • (19) The particular advantage of the method described here is the ease with which the supernatants can be collected and transferred to counting vials with minimal handling of radioactive samples.
  • (20) The greatest care should be exercised by industry in handling tremolite or materials contaminated with it.

Manipulate


Definition:

  • (v. t.) To treat, work, or operate with the hands, especially when knowledge and dexterity are required; to manage in hand work; to handle; as, to manipulate scientific apparatus.
  • (v. t.) To control the action of, by management; as, to manipulate a convention of delegates; to manipulate the stock market; also, to manage artfully or fraudulently; as, to manipulate accounts, or election returns.
  • (v. i.) To use the hands in dexterous operations; to do hand work; specifically, to manage the apparatus or instruments used in scientific work, or in artistic or mechanical processes; also, specifically, to use the hand in mesmeric operations.

Example Sentences:

  • (1) Similar experimental manipulation has yielded in vitro lines established from avian B-cell lymphomas expressing elevated levels of c-myc or v-rel.
  • (2) Technical factors that account for increased difficulty in these patients include: problems with guide catheter impaction and ostial trauma; inability to inflate the balloon with adequate guide catheter support; and need for increased intracoronary manipulation.
  • (3) aeruginosa and Enterococci) were significantly reduced in number during the manipulation (Fig.
  • (4) By growing purified human cytotrophoblasts under serum-free conditions and manipulating the culture surface, we were able to disassociate morphologic from biochemical differentiation.
  • (5) It would be "very easy to manipulate and access one of our vehicles", he said.
  • (6) Technical manipulations to improve resolution were time consuming and added little to the accuracy of the test.
  • (7) The prognosis was adversely affected by obesity, preoperative flexion contracture of 30 degrees or more, wound-healing problems, wound infection, and postoperative manipulation under general anesthesia.
  • (8) The intracranial pressure can then be studied and experimentally manipulated.
  • (9) Results show that responses to motion of cortical cells are particularly sensitive to these manipulations.
  • (10) Although a similar conjugation of the B polysaccharide failed to substantially enhance its immunogenicity in mice, this could be achieved by further chemical manipulation of the basic structure of the B polysaccharide.
  • (11) Given the liberalist context in which we live, this paper argues that an act-oriented ethics is inadequate and that only a virtue-oriented ethics enables us to recognize and resolve the new problems ahead of us in genetic manipulation.
  • (12) Thus, both energy intake and expenditure were manipulated to result in an energy deficit of 50 percent.
  • (13) The advantages of pars plana approach are the small incision and minimal ocular manipulation during surgery.
  • (14) For more than half a century, Saudi leaders manipulated the United States by feeding our oil addiction, lavishing money on politicians, helping to finance American wars, and buying billions of dollars in weaponry from US companies.
  • (15) Hogan-Howe said allegations, from three whistleblowers, that there is widespread manipulation of the figures are currently being investigated.
  • (16) A preliminary "profile" of the patient with low back pain who would likely benefit from manual therapy included acute symptom onset with less than a 1-month duration of symptoms, central or paravertebral pain distribution, no previous exposure to spinal manipulation, and no pending litigation or workers' compensation.
  • (17) Especially once the Libor scandal gave a clear signal of how markets could be manipulated.
  • (18) Micronutrient antioxidants such as alpha-tocopherol, the principal lipid-soluble antioxidant, assume potential significance because levels can be manipulated by dietary measures without resulting in side effects.
  • (19) Animals in Groups 2 and 3 underwent exposure and manipulation of the right ureter.
  • (20) Such analysis provides criteria, based on the response of the components to experimental manipulations, for identifying those aspects of the ERP recorded in other species that are analogous to specific ERP components recorded from human subjects.