What's the difference between handle and sickle?

Handle


Definition:

  • (v. t.) To touch; to feel with the hand; to use or hold with the hand.
  • (v. t.) To manage in using, as a spade or a musket; to wield; often, to manage skillfully.
  • (v. t.) To accustom to the hand; to work upon, or take care of, with the hands.
  • (v. t.) To receive and transfer; to have pass through one's hands; hence, to buy and sell; as, a merchant handles a variety of goods, or a large stock.
  • (v. t.) To deal with; to make a business of.
  • (v. t.) To treat; to use, well or ill.
  • (v. t.) To manage; to control; to practice skill upon.
  • (v. t.) To use or manage in writing or speaking; to treat, as a theme, an argument, or an objection.
  • (v. i.) To use the hands.
  • (n.) That part of vessels, instruments, etc., which is held in the hand when used or moved, as the haft of a sword, the knob of a door, the bail of a kettle, etc.
  • (n.) That of which use is made; the instrument for effecting a purpose; a tool.

Example Sentences:

  • (1) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
  • (2) The most successful dyes were phenocyanin TC, gallein, fluorone black, alizarin cyanin BB and alizarin blue S. Celestin blue B with an iron mordant is quite successful if properly handled to prevent gelling of solutions.
  • (3) "The Samaras government has proved to be dangerous; it cannot continue handling the country's fate."
  • (4) Control of cell calcium handling and transport may be abnormal in hypertension.
  • (5) Equal numbers of handled and unhandled puparia were planted out at different densities (1, 2, 4 or 8 per linear metre) in fifty-one natural puparial sites in four major vegetation types.
  • (6) Arrogant, narcissistic, egotistical, brilliant – all of that I can handle in Paul,” Levinson writes.
  • (7) Isolated renal tubules and renal clearance techniques were used to characterize the renal handling of 2-deoxy-D-galactose (2-d-Gal) by the winter flounder (Pseudopleuronectes americanus).
  • (8) In this study, we examined renal tubular cell handling of digoxin and ouabain using LLC-PK1 cells, a model of proximal renal tubular cells.
  • (9) Just before Christmas the independent Kerslake report severely criticised Birmingham city council for its dysfunctional politics and, in particular, its handling of the so-called Trojan Horse affair, in which school governors were said to have set out to bring about an Islamic agenda into the curriculum contents and the day-to-day running of some schools.
  • (10) The effects of insulin on the renal handling of sodium, potassium, calcium, and phosphate were studied in man while maintaining the blood glucose concentration at the fasting level by negative feedback servocontrol of a variable glucose infusion.
  • (11) The Nd-Yag-Laser seems to be a useful device in transsphenoidal surgery due to its potent coagulation effect and comfortable handling.
  • (12) Techniques are described for the special handling of these cells as well as suitable assay procedures.
  • (13) The decision of the editors to solicit a review for the Medical Progress series of this journal devoted to current concepts of the renal handling of salt and water is sound in that this important topic in kidney physiology has recently been the object of a number of new, exciting and, in some instances, quite unexpected insights into the mechanisms governing sodium excretion.
  • (14) Possible reasons for the previous discrepancies between direct and isotopic methods are discussed, as are the effects of protein binding, sample handling, and storage conditions on oxalate values in plasma.
  • (15) In addition to working with hist colleagues on general review and health-policy matters, he also handled issues related to the special needs of children and helped to get third-party benefit packages altered to better suit the treatment needs of children.
  • (16) Furthermore, this system can be satisfactory handled by technical personnel after short periods of training.
  • (17) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
  • (18) Both techniques are used by industry and regulatory agencies to monitor levels of fungal contamination at various stages of food handling, storing, processing and marketing.
  • (19) The particular advantage of the method described here is the ease with which the supernatants can be collected and transferred to counting vials with minimal handling of radioactive samples.
  • (20) The greatest care should be exercised by industry in handling tremolite or materials contaminated with it.

Sickle


Definition:

  • (n.) A reaping instrument consisting of a steel blade curved into the form of a hook, and having a handle fitted on a tang. The sickle has one side of the blade notched, so as always to sharpen with a serrated edge. Cf. Reaping hook, under Reap.
  • (n.) A group of stars in the constellation Leo. See Illust. of Leo.

Example Sentences:

  • (1) In addition, congenital anemias such as sickle cell disease can impact on the health of the mother and fetus.
  • (2) Sickle and normal discocytes both showed membrane elasticity with reversion to original cell shape following release of the cell from its aspirated position at the pipette tip.
  • (3) Fourier transform infrared (FTIR) spectroscopy was used to examine the effect of oxysterol insertion into normal and sickle RBC membranes and the total lipid extracts of the membranes.
  • (4) The initial screening failed to detect sickle cell anemia in 4 infants, but the hemoglobinopathy in 3 of these infants was diagnosed correctly by routine retesting of those with suspected sickle cell trait.
  • (5) The sources were two adolescent patients with sickle cell disease and aplastic crisis who had unsuspected parvovirus infection.
  • (6) Thus, an abnormality of neutrophil oxidative metabolism cannot explain the propensity to bacterial infections in sickle cell disease.
  • (7) In order to examine sickle cell blood flow during MR imaging in vivo, laser-Doppler velocimetry was performed in normal control subjects and in sickle cell subjects before, during, and after MR imaging at 0.35 and 1.5 T. Mean blood flow and patterns of blood-flow variability were compared by two hematologists.
  • (8) Calcium-dependent ATPase, adenylate cyclase and phosphorylation of erythrocyte membrane proteins have been found abnormal in various conditions: hereditary spherocytosis, sickle-cell anemia, progressive muscular dystrophies, all of these disorders being associated with a decreased deformability of the erythrocyte.
  • (9) Sickle cell anemia and other hemoglobinopathies represent a major health problem in the United States.
  • (10) This suggests that there is little survival advantage or disadvantage in the combination of glucose-6-phosphate dehydrogenase deficiency and sickle cell anaemia.
  • (11) We present a boy with sickle cell glomerulopathy and FSGS who is younger than patients with similar findings reported previously.
  • (12) Disruption of normal blood flow patterns in the medulla with impairment of function of the loop of Henle (functional papillectomy), presumably because of sickling in the hyperosmolar and anoxic environment of the renal medulla, may mediate these abnormalities.
  • (13) A study was conducted in a sample of 140 children with sickle cell anemia to evaluate the relationship between hematological variables (%HbF, %HbA2, %Hb, and mean cell volume) and disease severity.
  • (14) These include diseases diagnosed by restriction-site variation, such as Duchenne's muscular dystrophy and sickle cell anemia, those due to a collection of known mutations, such as beta-thalassemia, and those due to gene deletion, such as alpha-thalassemia.
  • (15) You’d think Michael Foot himself was running, attending debates in a hammer and sickle-print donkey jacket, from the amount we’ve been talking about him.
  • (16) Although these diseases are routinely screened for at birth, there is no general strategy among district health authorities for sickle cell screening.
  • (17) When red cells were loaded with Ca2+ using Ionophore A23187, both normal and sickle red cells enhanced their phosphorylation and sickle red cells to a greater extent than normal red cells.
  • (18) Nearly all sickle cell anemia patients carried the beta S mutation on a chromosome with haplotype 19 (or Benin) and all had severe anemia with sickling complications.
  • (19) The agent 12C79 which increases the oxygen affinity of sickle cells in vivo and prevent HbS polymerization is in clinical development.
  • (20) The results indicated that sickle cell patients have significant psychosocial distress in the areas of employment and finances, sleeping and eating, and performance of normal daily activities.