(v. t.) To touch; to feel with the hand; to use or hold with the hand.
(v. t.) To manage in using, as a spade or a musket; to wield; often, to manage skillfully.
(v. t.) To accustom to the hand; to work upon, or take care of, with the hands.
(v. t.) To receive and transfer; to have pass through one's hands; hence, to buy and sell; as, a merchant handles a variety of goods, or a large stock.
(v. t.) To deal with; to make a business of.
(v. t.) To treat; to use, well or ill.
(v. t.) To manage; to control; to practice skill upon.
(v. t.) To use or manage in writing or speaking; to treat, as a theme, an argument, or an objection.
(v. i.) To use the hands.
(n.) That part of vessels, instruments, etc., which is held in the hand when used or moved, as the haft of a sword, the knob of a door, the bail of a kettle, etc.
(n.) That of which use is made; the instrument for effecting a purpose; a tool.
Example Sentences:
(1) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
(2) The most successful dyes were phenocyanin TC, gallein, fluorone black, alizarin cyanin BB and alizarin blue S. Celestin blue B with an iron mordant is quite successful if properly handled to prevent gelling of solutions.
(3) "The Samaras government has proved to be dangerous; it cannot continue handling the country's fate."
(4) Control of cell calcium handling and transport may be abnormal in hypertension.
(5) Equal numbers of handled and unhandled puparia were planted out at different densities (1, 2, 4 or 8 per linear metre) in fifty-one natural puparial sites in four major vegetation types.
(6) Arrogant, narcissistic, egotistical, brilliant – all of that I can handle in Paul,” Levinson writes.
(7) Isolated renal tubules and renal clearance techniques were used to characterize the renal handling of 2-deoxy-D-galactose (2-d-Gal) by the winter flounder (Pseudopleuronectes americanus).
(8) In this study, we examined renal tubular cell handling of digoxin and ouabain using LLC-PK1 cells, a model of proximal renal tubular cells.
(9) Just before Christmas the independent Kerslake report severely criticised Birmingham city council for its dysfunctional politics and, in particular, its handling of the so-called Trojan Horse affair, in which school governors were said to have set out to bring about an Islamic agenda into the curriculum contents and the day-to-day running of some schools.
(10) The effects of insulin on the renal handling of sodium, potassium, calcium, and phosphate were studied in man while maintaining the blood glucose concentration at the fasting level by negative feedback servocontrol of a variable glucose infusion.
(11) The Nd-Yag-Laser seems to be a useful device in transsphenoidal surgery due to its potent coagulation effect and comfortable handling.
(12) Techniques are described for the special handling of these cells as well as suitable assay procedures.
(13) The decision of the editors to solicit a review for the Medical Progress series of this journal devoted to current concepts of the renal handling of salt and water is sound in that this important topic in kidney physiology has recently been the object of a number of new, exciting and, in some instances, quite unexpected insights into the mechanisms governing sodium excretion.
(14) Possible reasons for the previous discrepancies between direct and isotopic methods are discussed, as are the effects of protein binding, sample handling, and storage conditions on oxalate values in plasma.
(15) In addition to working with hist colleagues on general review and health-policy matters, he also handled issues related to the special needs of children and helped to get third-party benefit packages altered to better suit the treatment needs of children.
(16) Furthermore, this system can be satisfactory handled by technical personnel after short periods of training.
(17) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
(18) Both techniques are used by industry and regulatory agencies to monitor levels of fungal contamination at various stages of food handling, storing, processing and marketing.
(19) The particular advantage of the method described here is the ease with which the supernatants can be collected and transferred to counting vials with minimal handling of radioactive samples.
(20) The greatest care should be exercised by industry in handling tremolite or materials contaminated with it.
Use
Definition:
(v. t.) The act of employing anything, or of applying it to one's service; the state of being so employed or applied; application; employment; conversion to some purpose; as, the use of a pen in writing; his machines are in general use.
(v. t.) Occasion or need to employ; necessity; as, to have no further use for a book.
(v. t.) Yielding of service; advantage derived; capability of being used; usefulness; utility.
(v. t.) Continued or repeated practice; customary employment; usage; custom; manner; habit.
(v. t.) Common occurrence; ordinary experience.
(v. t.) The special form of ritual adopted for use in any diocese; as, the Sarum, or Canterbury, use; the Hereford use; the York use; the Roman use; etc.
(v. t.) The premium paid for the possession and employment of borrowed money; interest; usury.
(v. t.) The benefit or profit of lands and tenements. Use imports a trust and confidence reposed in a man for the holding of lands. He to whose use or benefit the trust is intended shall enjoy the profits. An estate is granted and limited to A for the use of B.
(v. t.) A stab of iron welded to the side of a forging, as a shaft, near the end, and afterward drawn down, by hammering, so as to lengthen the forging.
(v. t.) To make use of; to convert to one's service; to avail one's self of; to employ; to put a purpose; as, to use a plow; to use a chair; to use time; to use flour for food; to use water for irrigation.
(v. t.) To behave toward; to act with regard to; to treat; as, to use a beast cruelly.
(v. t.) To practice customarily; to make a practice of; as, to use diligence in business.
(v. t.) To accustom; to habituate; to render familiar by practice; to inure; -- employed chiefly in the passive participle; as, men used to cold and hunger; soldiers used to hardships and danger.
(v. i.) To be wont or accustomed; to be in the habit or practice; as, he used to ride daily; -- now disused in the present tense, perhaps because of the similarity in sound, between "use to," and "used to."
(v. i.) To be accustomed to go; to frequent; to inhabit; to dwell; -- sometimes followed by of.
Example Sentences:
(1) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
(2) These variants may serve as useful gene markers in alcohol research involving animal model studies with inbred strains in mice.
(3) Therefore, these findings may extend the use of platelets as neuronal models.
(4) All transplants were performed using standard techniques, the operation for the two groups differing only as described above.
(5) The resulting dose distribution is displayed using traditional 2-dimensional displays or as an isodose surface composited with underlying anatomy and the target volume.
(6) It was tested for recovery and separation from other selenium moieties present in urine using both in vivo-labeled rat urine and human urine spiked with unlabeled TMSe.
(7) A study revealed that the percentage of active sperm in semen 30 seconds after ejaculation was 10.3% when a nonoxynol 9 latex condom was used as opposed to 55.9% in a nonspermicidal condom.
(8) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(9) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(10) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
(11) Spectral analysis of spontaneous heart rate fluctuations, a powerful noninvasive tool for quantifying autonomic nervous system activity, was assessed in Xenopus Laevis, intact or spinalized, at different temperatures and by use of pharmacological tools.
(12) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(13) Questionnaires were used and the respondent self-designation method measured leadership.
(14) At 36 h postsurgery, RBCs were examined by 23Na-NMR by using dysprosium tripolyphosphate as a chemical shift reagent.
(15) Biochemical, immunocytochemical and histochemical methods were used to study the effect of chronic acetazolamide treatment on carbonic anhydrase (CA) isoenzymes in the rat kidney.
(16) Use of the improved operative technique contributed to reduction in number of complications.
(17) Down and up regulation by peptides may be useful for treatment of cough and prevention of aspiration pneumonia.
(18) Our data suggest that a rational use of surveillance cultures and serological tests may aid in an earlier diagnosis of FI in BMT patients.
(19) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(20) Models able to describe the events of cellular growth and division and the dynamics of cell populations are useful for the understanding of functional control mechanisms and for the theoretical support for automated analysis of flow cytometric data and of cell volume distributions.