(a.) Made hard, or compact; made unfeeling or callous; made obstinate or obdurate; confirmed in error or vice.
Example Sentences:
(1) Osmotically treated red cells, red cells partially hardened with increasing glutaraldehyde concentrations, and mixtures of normal and hardened red cells were used to test the method.
(2) "But if public opposition to further austerity measures hardens, the Greek government could find it even tougher to put the public finances back on a sustainable footing."
(3) It's not as if they were once tolerant and have hardened their hearts as they've grown older.
(4) Insertion of an adequate approximate amalgam filling and its finish after hardening is one of the basic preventive measures in marginal periodontopathies.
(5) Hardened skin was markedly altered physiologically.
(6) A comparison was made of the kinetics of the carboxylation reaction of bicarbonate-magnesium-activated ribulose biphosphate carboxylase-oxygenase purified from cold-hardened and unhardened winter rye (Secale cereale L. cv.
(7) Rarely has there been a potential presidential candidate so battle-hardened and ready for combat.
(8) With its huge corps of jihadists hardened by years of fighting in Kashmir, it is arguably too big to confront at a time when Pakistan is battling the TTP.
(9) However, several systematic errors of the method have to be considered, such as the influence of fat present in the spongiosa in varying concentrations as well as beam hardening effects and different calibration methods.
(10) It is the sort of malevolent onslaught that has caused many hardened media pundits to quake.
(11) Values of elongation were more than 10% even after hardening heat treatment.
(12) It’s not an entirely controversy-free choice, considering that Harden hasn’t been a starter for more than two seasons, doesn’t have the best track record as far as being a team player goes and at times has been bad enough on defense that you could make an entire YouTube playlist devoted entirely to clips of him failing to make any defensive effort whatsoever.
(13) Compared to conventional CT, the new system should significantly improve contrast resolution of the image and provide better image quantification because of its lack of beam-hardening effects and its efficient implementation of energy-selective imaging methods such as dual-photon absorptiometry and K-edge subtraction with high-atomic-number (high-Z) contrast-enhancement elements.
(14) An earlier debt sustainability analysis was leaked in the days leading up to the Greek referendum and helped harden opposition to the (less draconian) terms then on offer.
(15) He also signalled a change in policy on welfare, hardening Labour’s opposition to the government’s welfare reforms, by pledging to oppose the cap on the total amount of benefits that a person can receive.
(16) The effects of DMSO and cooling on fertilization are likely to be due to zona hardening by cortical granule release and to disorganization of the egg cytoskeleton and plasma membrane.
(17) When present during the egg activation process monodansylcadaverine (MDC-a fluorescent lysine analog) inhibits eggshell hardening and at the same time becomes covalently incorporated into the eggshell.
(18) In rigor control, crossbridges were most regular in muscles that were stabilized before freezing by prefixation in glutaraldehyde followed by 'hardening' with neutralized tannic acid, so all nucleotide treatments were terminated by such fixation.
(19) It main advantage lies in the screening of arterial diseases (very reproductable and sensitive), monitoring of the treatment (unrelated to the operator), study of hardened arteries (diabetes).
(20) Evidence from several sources indicate that the catalytic action of the peroxidase is responsible for hardening the FE through the phenolic coupling of tyrosyl residues of the FE proteins.
(a.) Confident; full of assurance; in a bad sense, morally hardened; shameless.
(a.) Strong; firm; compact.
(a.) Inured to fatigue or hardships; strong; capable of endurance; as, a hardy veteran; a hardy mariner.
(a.) Able to withstand the cold of winter.
(n.) A blacksmith's fuller or chisel, having a square shank for insertion into a square hole in an anvil, called the hardy hole.
Example Sentences:
(1) Twenty drug-free patients (12 women and 8 men) meeting DSM-III criteria for major depressive disorder were given the Kobasa Hardiness Questionnaire, which contains subscales measuring feelings of powerlessness, security, and alientation.
(2) Hardy has a 10in tattoo of Lee along his left shin.
(3) It is suggested that this early immune maturity may play a role in the hardiness of WAD goats and in their relative resistance to helminth and protozoan infection as compared with local sheep.
(4) A heat source contained in a modified Hardy-Wolff-Goodell dolorimeter was used as a stimulus to produce pain on the posterolateral aspects of the left forearms of volunteer subjects.
(5) Hardy headlines as an ex-con named Bob Saginowski who is trying to live out a quiet life away from crime as a bartender.
(6) There weren't many people out on their bikes in Harrogate over the weekend: the weather was too poor even for hardy Yorkshire folk.
(7) Most critical are (a) how hardiness is to be measured; (b) whether hardiness should be treated as a unitary phenomenon or as three separate phenomena associated with commitment, control, and challenge; and (c) whether hardiness has direct effects on health or indirect effects by virtue of buffering the impact of stressful life events.
(8) Gene frequencies were compared with previous data and all European populations studied so fare agreed with the Hardy-Weinberg equilibrium.
(9) The number of people in the group corresponded to the theoretical number of heterozygotes in accordance with the Hardy-Weinberg equation, suggesting that sucrase deficiency is recessively inherited in a simple Mendelian fashion.
(10) The study findings did not support the buffering effects of hardiness in the presence of greater amounts of stress.
(11) Vegetation is low, widely spaced and hardy, most of it armed with spines.
(12) The favorable morphology and hardiness in organ culture of this preparation have permitted a wide range of electrophysiological, cellular, and molecular studies.
(13) Departures from the Hardy-Weinberg expectations, indicating an excess of heterokaryotypes, were noted and critically analysed by comparing samples obtained simultaneously in the same locality from different cow sheds, from different sections of the same cow shed and from night and day catches in the same cow shed.
(14) The distribution of the Blast-1 genotypes in the present study was concordant with Hardy-Weinberg equilibrium (p greater than 0.7), which indicates that the frequency of the Blast-1 gene in the population is derived from random mating in preceding generations.
(15) The observed frequency distribution of individuals with homozygous NOR-positive, heterozygous, and homozygous negative acrocentric chromosomes was in accordance with the Hardy-Weinberg law in all five pairs of the acrocentric chromosomes as well as in total.
(16) Over 42% of the variance in family functioning was accounted for by family hardiness, functional support, family stressors, and parental age.
(17) Facebook Twitter Pinterest Tom Hardy and George Miller at the press conference.
(18) Theoretical estimates were made of the chronological decrease in the incidence using a formula for Hardy-Weinberg expectation in a partially inbred population and applying appropriate consanguinity rates, taken from the literature, during the period from 1942 to 1983.
(19) An experiment is reported which tests Fazey & Hardy's (1988) catastrophe model of anxiety and performance.
(20) Another thing is that scientists like Sarah Hardy have been able to demonstrate a far greater richness of female flexibility in reproductive strategies.