(a.) Made hard, or compact; made unfeeling or callous; made obstinate or obdurate; confirmed in error or vice.
Example Sentences:
(1) Osmotically treated red cells, red cells partially hardened with increasing glutaraldehyde concentrations, and mixtures of normal and hardened red cells were used to test the method.
(2) "But if public opposition to further austerity measures hardens, the Greek government could find it even tougher to put the public finances back on a sustainable footing."
(3) It's not as if they were once tolerant and have hardened their hearts as they've grown older.
(4) Insertion of an adequate approximate amalgam filling and its finish after hardening is one of the basic preventive measures in marginal periodontopathies.
(5) Hardened skin was markedly altered physiologically.
(6) A comparison was made of the kinetics of the carboxylation reaction of bicarbonate-magnesium-activated ribulose biphosphate carboxylase-oxygenase purified from cold-hardened and unhardened winter rye (Secale cereale L. cv.
(7) Rarely has there been a potential presidential candidate so battle-hardened and ready for combat.
(8) With its huge corps of jihadists hardened by years of fighting in Kashmir, it is arguably too big to confront at a time when Pakistan is battling the TTP.
(9) However, several systematic errors of the method have to be considered, such as the influence of fat present in the spongiosa in varying concentrations as well as beam hardening effects and different calibration methods.
(10) It is the sort of malevolent onslaught that has caused many hardened media pundits to quake.
(11) Values of elongation were more than 10% even after hardening heat treatment.
(12) It’s not an entirely controversy-free choice, considering that Harden hasn’t been a starter for more than two seasons, doesn’t have the best track record as far as being a team player goes and at times has been bad enough on defense that you could make an entire YouTube playlist devoted entirely to clips of him failing to make any defensive effort whatsoever.
(13) Compared to conventional CT, the new system should significantly improve contrast resolution of the image and provide better image quantification because of its lack of beam-hardening effects and its efficient implementation of energy-selective imaging methods such as dual-photon absorptiometry and K-edge subtraction with high-atomic-number (high-Z) contrast-enhancement elements.
(14) An earlier debt sustainability analysis was leaked in the days leading up to the Greek referendum and helped harden opposition to the (less draconian) terms then on offer.
(15) He also signalled a change in policy on welfare, hardening Labour’s opposition to the government’s welfare reforms, by pledging to oppose the cap on the total amount of benefits that a person can receive.
(16) The effects of DMSO and cooling on fertilization are likely to be due to zona hardening by cortical granule release and to disorganization of the egg cytoskeleton and plasma membrane.
(17) When present during the egg activation process monodansylcadaverine (MDC-a fluorescent lysine analog) inhibits eggshell hardening and at the same time becomes covalently incorporated into the eggshell.
(18) In rigor control, crossbridges were most regular in muscles that were stabilized before freezing by prefixation in glutaraldehyde followed by 'hardening' with neutralized tannic acid, so all nucleotide treatments were terminated by such fixation.
(19) It main advantage lies in the screening of arterial diseases (very reproductable and sensitive), monitoring of the treatment (unrelated to the operator), study of hardened arteries (diabetes).
(20) Evidence from several sources indicate that the catalytic action of the peroxidase is responsible for hardening the FE through the phenolic coupling of tyrosyl residues of the FE proteins.
Incorrigible
Definition:
(a.) Not corrigible; incapable of being corrected or amended; bad beyond correction; irreclaimable; as, incorrigible error.
(n.) One who is corrigible; especially, a hardened criminal; as, the perpetual imprisonment of incorrigibles.
Example Sentences:
(1) He may be victim of an incorrigible cronyism, and his overdue attempt to reform Britain’s welfare state has left many rough edges, some of them inexcusable.
(2) But more importantly, the museum's exhibitions keep surfacing the "incorrigible plurality" – as the poet Louis MacNeice put it – of human beings and how that manifests in the communities, nation states and empires they build.
(3) Journalists have colluded in the self-pleasuring of Boris Johnson by obsessing over which side of the fence that incorrigible attention-seeker will fall.
(4) Police suspect global Project was actually made-up: a cover story or “legend” designed to disguise the real purpose of Kovtun and Lugovoi’s trip to London, which was to murder a man long regarded by the Kremlin as an incorrigible traitor.
(5) For a start, it is impossible: incorrigibility is the defining characteristic of the hardcore Kippers.
(6) Exarticulation according to Syme was resorted in order to cope with an incorrigible abnormal position of the foot and for leg length inequality.
(7) And there are entries that point to Peel as an incorrigible collector and tireless champion of the recherche: with all due respect to an oeuvre that included the piquant-sounding Fuckin' 4 Bucks and I'll Be Glad When You're Dead, how many albums by Washington DC splattercore pioneers the Accüsed does one man really need?
(8) But they are more or less ignorant, and it is that we call vice or virtue; the most incorrigible vice being that of an ignorance which fancies it knows everything and therefore claims for itself the right to kill."
(9) Eve Ensler and her incorrigible team have done so much to bring about this campaign.
(10) After she accused a neighbour of attempting to rape her, the 10-year-old Holiday, an incorrigible truant, was sent to a Catholic reform school until her mother secured her release.
(11) In fact, being drawn so narrowly from the category Occasion Wear, the costumes and photographs could scarcely have been better chosen to overlay memories of the surge of royal-blaming that Diana’s death inspired in 1997 – of her own reinvention as a global charity envoy and amateur healer, of her appointment as feminist heroine as well as tabloid goddess and, above all, of her magnificent achievements as the royal family’s incorrigible, lead tormentor.
(12) Continental Europeans often assume that England is, in its heart of oak, incorrigibly hostile to Europe.
(13) Later the infant will be operated, longer be will keep glottal stops may be incorrigible.
(14) It wasn't just that I was blind, which people seemed to find very interesting and therefore took a lot of notice of me, which as an incorrigible showoff I liked.
(15) He was described as seeming almost to be ‘obsessed with women’, and an ‘incorrigible womaniser’.” One female editorial member of the team gave evidence about “the almost daily sexual harassment” experienced at the hands of Hall.
(16) As trade secretary, he would be incorrigibly illiberal, refusing landing rights to Freddie Laker's Skytrain and being duly overruled by the high court.
(17) It can be traced back to Karl Jaspers who was the first to mention the three criteria of delusions, which are to be found in the textbooks ever since: (1) certainty, (2) incorrigibility, and (3) impossibility or falsity of content.
(18) As Marston sails for Europe, watching America recede into his past, Fitzgerald offers a closing meditation nearly as incantatory as the famous conclusion of Gatsby: "Watching the fading city, the fading shore, from the deck of the Majestic, he had a sense of overwhelming gratitude and of gladness that America was there, that under the ugly débris of industry the rich land still pushed up, incorrigibly lavish and fertile, and that in the heart of the leaderless people the old generosities and devotions fought on, breaking out sometimes in fanaticism and excess, but indomitable and undefeated.
(19) There's something incorrigibly Manchester about them in the same way that Happy Mondays are also typically Mancunian.
(20) Seven principles under Talmudic Law are discussed which were used by the Court to help determine whether or not an individual was in fact an incorrigible delinquent.