(a.) Made hard, or compact; made unfeeling or callous; made obstinate or obdurate; confirmed in error or vice.
Example Sentences:
(1) Osmotically treated red cells, red cells partially hardened with increasing glutaraldehyde concentrations, and mixtures of normal and hardened red cells were used to test the method.
(2) "But if public opposition to further austerity measures hardens, the Greek government could find it even tougher to put the public finances back on a sustainable footing."
(3) It's not as if they were once tolerant and have hardened their hearts as they've grown older.
(4) Insertion of an adequate approximate amalgam filling and its finish after hardening is one of the basic preventive measures in marginal periodontopathies.
(5) Hardened skin was markedly altered physiologically.
(6) A comparison was made of the kinetics of the carboxylation reaction of bicarbonate-magnesium-activated ribulose biphosphate carboxylase-oxygenase purified from cold-hardened and unhardened winter rye (Secale cereale L. cv.
(7) Rarely has there been a potential presidential candidate so battle-hardened and ready for combat.
(8) With its huge corps of jihadists hardened by years of fighting in Kashmir, it is arguably too big to confront at a time when Pakistan is battling the TTP.
(9) However, several systematic errors of the method have to be considered, such as the influence of fat present in the spongiosa in varying concentrations as well as beam hardening effects and different calibration methods.
(10) It is the sort of malevolent onslaught that has caused many hardened media pundits to quake.
(11) Values of elongation were more than 10% even after hardening heat treatment.
(12) It’s not an entirely controversy-free choice, considering that Harden hasn’t been a starter for more than two seasons, doesn’t have the best track record as far as being a team player goes and at times has been bad enough on defense that you could make an entire YouTube playlist devoted entirely to clips of him failing to make any defensive effort whatsoever.
(13) Compared to conventional CT, the new system should significantly improve contrast resolution of the image and provide better image quantification because of its lack of beam-hardening effects and its efficient implementation of energy-selective imaging methods such as dual-photon absorptiometry and K-edge subtraction with high-atomic-number (high-Z) contrast-enhancement elements.
(14) An earlier debt sustainability analysis was leaked in the days leading up to the Greek referendum and helped harden opposition to the (less draconian) terms then on offer.
(15) He also signalled a change in policy on welfare, hardening Labour’s opposition to the government’s welfare reforms, by pledging to oppose the cap on the total amount of benefits that a person can receive.
(16) The effects of DMSO and cooling on fertilization are likely to be due to zona hardening by cortical granule release and to disorganization of the egg cytoskeleton and plasma membrane.
(17) When present during the egg activation process monodansylcadaverine (MDC-a fluorescent lysine analog) inhibits eggshell hardening and at the same time becomes covalently incorporated into the eggshell.
(18) In rigor control, crossbridges were most regular in muscles that were stabilized before freezing by prefixation in glutaraldehyde followed by 'hardening' with neutralized tannic acid, so all nucleotide treatments were terminated by such fixation.
(19) It main advantage lies in the screening of arterial diseases (very reproductable and sensitive), monitoring of the treatment (unrelated to the operator), study of hardened arteries (diabetes).
(20) Evidence from several sources indicate that the catalytic action of the peroxidase is responsible for hardening the FE through the phenolic coupling of tyrosyl residues of the FE proteins.
Obdurate
Definition:
(a.) Hardened in feelings, esp. against moral or mollifying influences; unyielding; hard-hearted; stubbornly wicked.
(a.) Hard; harsh; rugged; rough; intractable.
(v. t.) To harden.
Example Sentences:
(1) The system is not an obdurate one-man rule, but a balancing of power groups, including the military, government and internal security, all have different interests and policies.
(2) Both the Coalition and Labor are obdurately stuck with barbaric offshore detention policies, as though sensible, humane and politically viable alternatives are beyond them.
(3) For their part, the Israeli left accused Peres of acting as a figleaf for an obdurate Likud administration.
(4) Report on the temporary substitution of pharynx and upper oesophagus with synthetic skin substitute in case of incurable obdurating neck carcinoma.
(5) His team-mates were obdurate opponents in every respect.
(6) The fact that it was Johnson rather than Crow who had been obdurate was highlighted by the fact that TfL had all along planned to retain ticket-selling facilities at several busy stations, but, prompted by Johnson, had publicly suggested that they would all be closed.
(7) For the first time there were obvious signs of tension and, suddenly, this tough, obdurate West Bromwich side showed an attacking intent that simply had not been there earlier in the match.
(8) In the face of obdurate unreason, the president of hyper-reasonableness was forced to surrender.
(9) Underpinning the witty remarks and the textbook flippancy ("call me early, Goering dear, for I'm to be Queen of the May" was apparently Nancy's riposte to news of Diana and Unity's German adventures) though, was an absolute and obdurate self-belief; a self-possessed seriousness only partly disguised by sisterly teasing.
(10) Max from Earlsfield muses: "Admittedly terrible from Fab, a shame after 47 minutes of obdurate defence.
(11) This was a slog, a result ground out against ruggedly obdurate opposition , but Chelsea may end up gaining more satisfaction from prevailing in those awkward circumstances than from some of the more comfortable strolls they have enjoyed over a nine-match winning streak.
(12) Read more It was the third minute of stoppage time, and the cruellest of circumstances for this tough, obdurate Burnley side, when Arsenal’s possession finally paid off and the seemingly endless 20th-anniversary commemorations for Arsène Wenger were given a shot of euphoria that had not seemed like coming.
(13) Ireland were obdurate opponents but that does not fully explain the lack of quality that held back England once Frank Lampard had scored the 29th goal of his international career, 10 minutes after Shane Long's expertly taken header had given Giovanni Trapattoni's side an early lead.
(14) Russia's determination to defend wider spheres of traditional influence in the non-aligned and developing world can be seen in its obdurate refusal to penalise Syria, in the face of almost universal outrage over the crackdown there; and in its de facto defence of Iran's nuclear programme.
(15) It had needed some obdurate defending to keep the score down before Alves exchanged passes with the substitute Neymar and cut in from the right to slip his shot through Hart's legs.
(16) Republicans have been both obdurate and obtuse in Congress, where approval ratings have rarely scraped 20%.
(17) He is assertive (he insists on his photographer and dictates the terms of the interview), obdurate and, at times, wilfully contrary.
(18) We had an obdurate Labor party, a feckless Senate and a very difficult media culture,” Abbott said.
(19) In the years since those facts first became known, the story of the Holocaust has been told and retold, yet it still remains obdurately difficult to tell.
(20) Giles also remained obdurate and continued to refuse to resign even though he had only four supporters as against the conspirators’ nine.