(n.) That which is hard to hear, as toil, privation, injury, injustice, etc.
Example Sentences:
(1) A failure to reach a solution would potentially leave 200,000 homes without affordable cover, leaving owners unable to sell their properties and potentially exposing them to financial hardship.
(2) The findings provide additional evidence that, for at least some cases, the likelihood of a physician's admitting a patient to the hospital is influenced by the patient's living arrangements, travel time to the physician's office, and the extent to which medical care would cause a financial hardship for the patient.
(3) Actions achieved or a long commitment to an ideal, often through hardship.
(4) The Kremlin has so far refrained from dealing with mounting anger against people from Russia's turbulent North Caucasus region, as well as migrant workers from central Asia, which has grown as the country's oil-fuelled economic boom has given way to the hardship of the global financial crisis.
(5) We don't want to harm ourselves; we don't want suffering; we don't want hardship; we don't accept difficulty and disappointment.
(6) Woman at centre of South Korean row says she 'deserves death' Read more Presidential spokesman Jung Youn-kuk said: “The Blue House named Kim as the right person to lead the cabinet for the country’s future and to overcome current hardships.” Yim Jong-yong, the Financial Services Commission chairman, was named the new finance minister and deputy prime minister.
(7) He also thanked nearly everyone who had been involved in the trial: his attorneys, his family, everyone who testified “with dignity” about their “unbearable” hardships.
(8) There will be a hardship waiver for those individuals who still cannot afford coverage, and 95% of all small businesses, because of their size and narrow profit margin, would be exempt from these requirements.
(9) For Paralympians, training and competition is an escape from the hardships and struggles of their everyday life.
(10) He was only four-years-old then, way too young to understand the hardships of life.
(11) But take back the initiative – because we've seen what happens when we let politicians take sole responsibility for how we organise our society: it's resulted in profound economic failure and material hardship.
(12) When combined with economic hardship, this loss makes the jobless more likely to suffer depression and even to take their own lives, as starkly shown by Sanjay Basu and David Stuckler in The Body Economic .
(13) The intimacy between community members and the doctor's own friendships with families, the distance to specialized services and the hardship travel might cause for patients, the economic risks in treating indigents in an already financially strapped small facility, and the physician's role as a citizen as well as health care provider are factors that cannot be ignored in treatment decisions.
(14) Already, 34 families have been given emergency hardship grants totalling more than £23,000, as the county offers them a lifeline.
(15) Is it hopelessly old fart-ish to hope exposure that to the horrors described by Buergenthal will remind all of us of the piffling nature of our next household conflagration about who gets to wear which pair of jeans, or whether homework on the weekend really constitutes a hardship – or even, somehow, temper the demand for new electronic equipment?
(16) Others argue that younger people are less used to dealing with hardship than their parents' generation and lack the resilience to cope with problems.
(17) I understood why our claims history had come back to bite us but still complained that, in these times of hardship, paying nearly £9 more each month was too much.
(18) Bellows is known for his powerful paintings representing the hardship and desperation and grittiness of life in New York as it emerged in to the 20th century.
(19) Despite years of violence, hardship and bitterly disputed votes, the hopeful mood suggested many feel change is finally within their grasp.
(20) Data on the economic status, number of rooms per household, number of persons per household, type of water supply, and mode of excreta disposal revealed that the majority of the population surveyed lived with economic hardship, overcrowding and poor hygiene.
Tolerance
Definition:
(n.) The power or capacity of enduring; the act of enduring; endurance.
(n.) The endurance of the presence or actions of objectionable persons, or of the expression of offensive opinions; toleration.
(n.) The power possessed or acquired by some persons of bearing doses of medicine which in ordinary cases would prove injurious or fatal.
Example Sentences:
(1) within 12 h of birth followed by similar injections every day for 10 consecutive days and then every second day for a further 8 weeks, with mycoplasma broth medium (tolerogen), to induce immune tolerance.
(2) No differences between the two substances were observed with respect to side effects and general tolerability.
(3) This treatment is usually well tolerated but not devoid of systemic effects.
(4) Well tolerated from the clinical and laboratory points of view, it proved remarkably effective.
(5) To estimate the age of onset of these differences, and to assess their relationship to abdominal and gluteal adipocyte size, we measured adiposity, adipocyte size, and glucose and insulin concentrations during a glucose tolerance test in lean (less than 20% body fat), prepubertal children from each race.
(6) Although temazepam was effective for maintaining sleep with short-term use, there was rapid development of tolerance for this effect with intermediate-term use.
(7) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(8) There were no biochemical or haematological abnormalities caused by prazosin but on continued therapy 16 patients developed tolerance to its effect.
(9) Characerization of further parameters such as relative susceptibility to tolerance induction and relative degree of specificity was not possible with the use of KLH as the antigen.
(10) Because of these different direct and indirect actions, a sudden cessation of sinus node activity or sudden AV block may result in the diseased heart in a prolonged and even fatal cardiac standstill, especially if the tolerance to ischemia of other organs (notably the brain) is decreased.
(11) Efficacy and tolerability of perorally administered desmopressin were evaluated in 12 adult patients suffering from central diabetes insipidus.
(12) This suggests that both blood transfusion and allograft are required for IL2 suppression and that this suppression may be related to the heart tolerance.
(13) At present, ACE inhibitors are preferred because they are usually better tolerated than conventional vasodilators and are clinically more effective.
(14) Changes in pain tolerance after administration of differently labelled placebos were studied by measuring the reaction time after a cold stimulus.
(15) TK1 showed the most restricted substrate specificity but tolerated 3'-modifications of the sugar ring and some 5-substitutions of the pyrimidine ring.
(16) Provided that adequate reflection is given and the appropriate moment chosen, it is well tolerated and provides all the necessary information.
(17) After large bowel removal, there was impaired glucose tolerance and attenuated plasma insulin secretion.
(18) Cardiac pump function is not affected, even in patients with ventricular dysfunction or heart failure, in whom chronic oral administration of the drug is well tolerated.
(19) These agents have been well-tolerated and generally produce a high incidence of sustained improvements in neutrophil counts and marrow morphology, although hemoglobin and platelet counts have generally not been altered.
(20) The above treatment is tolerated well and no serious side effects have been observed.