What's the difference between harmine and harming?
Harmine
Definition:
(n.) An alkaloid accompanying harmaline (in the Peganum harmala), and obtained from it by oxidation. It is a white crystalline substance.
Example Sentences:
(1) However, in hepatocytes from phenobarbital treated rats, where the rate of harmine metabolism is increased about five times and the main metabolite is harmol glucuronide, phenolphthalein glucuronide inhibited the formation of the conjugate with a concomitant increase in free harmol.
(2) MAO substrate specificity to tyramine, benzylamine, and serotinin along with selective inhibition by harmine, pargyline, and clorgyline were used as indices of multiple enzymic forms.
(3) Aprotinin may decrease or increase the blood-brain barrier permeability of harmine.
(4) Nomifensine reduced the intensity of harmine-induced tremor.
(5) The data suggest that the integrity of the paleostriatum is more important than that of the neostriatum for the mediation of harmine tremor and its antagonism by dopaminergic agonists.
(6) Several naturally occurring aromatic amines especially 2-carboline derivatives such as harman, norharman, harmaline, harmalol, harmine and harmol are mutagenic and become more mutagenic to Salmonella typhimurium after nitrosation.
(7) The brain lesion technique was used to investigate the role of the paleostriatum and the nigro-neostriatum in harmine-induced tremor and in its antagonism by dopaminergic agonists, apomorphine, 1-dopa, piribedil, d- and l-amphetamine.
(8) Harmine (HA) induces a jumping behavior in rats when the central dopaminergic function has been activated.
(9) The brain lesion technique was used to destroy the ascending 5-hydroxytryptamine (5-HT) system at its cell bodies in the dorsal and medial raphe nuclei in order to assess the importance of 5-HT for the induction of harmine tremor and its antagonism by the dopaminergic agonists, L-DOPA, apomorphine and d-amphetamine.
(10) The beta-carboline harmine was found to facilitate lordosis behavior in ovariectomized rats primed with estradiol benzoate.
(11) The mutagenicities of other carboline derivatives such as harman, norharman, harmaline, harmalol, harmine, and harmol were studied.
(12) The partially competitive nature of inhibition by one of the more effective pairs, 2-methyl-harmine and harmine, was consistent with uptake of the beta-carbolines by the synaptosomal dopamine uptake system, as was the fact that the accumulation of 2-[14C]methyl-harmine was significantly reduced by low Na+ media and by nomifensine, a potent inhibitor of the dopamine transporter.
(13) at the peak of the harmine effect, tremors subside.
(14) In ethanol-withdrawn rats treated with harmine or LON-954 the frequency analysis of tremor revealed a narrow peak frequency at about 12 Hz, which was neither the characteristic frequency of ethanol withdrawal tremor (6 Hz) nor that of harmine or LON-954 (10 Hz).
(15) Tissue subfractionation showed that 30% of the harmine in whole brain homogenates was in the P2 fraction, and of this, 70% was located in the synaptosomes.
(16) Since harmine-induced behavioural changes in mice are reported to be mediated through central serotonergic receptors, an attempt was made to test whether 1-propranolol would also modify harmine-induced responses by virtue of its anti-serotonergic or anti-adrenergic property.
(17) In rats with lymphostatic encephalopathy harmine concentrations in brain at the termination of tremor lay in the same range as in sham-operated controls.
(18) Clonidine exhibited a dose-dependent protection against harmine-induced tremors in mice.
(19) These results suggest that harmine facilitates lordosis by enhancing activity at 5-HT2 receptors.
(20) Prior studies indicate that the monoamine oxidase inhibitors (MAOI) harmine and iproniazide inhibit N-acetyltransferase activity from liver.
Harming
Definition:
(p. pr. & vb. n.) of Harm
Example Sentences:
(1) Chapman and the other "illegals" – sleeper agents without diplomatic cover – seem to have done little to harm American national security.
(2) Bacterial lipopolysaccharides (LPS), which are important components of the cell wall of gram-negative bacteria, induce a number of host responses both beneficial and harmful.
(3) Robert Francis QC's official report in February on the Mid Staffordshire care scandal, in which an estimated 400 to 1,200 patients died unnecessarily at Stafford hospital between 2005 and 2008, called for the NHS to make "zero harm" its objective.
(4) I realise now that the drug is far less harmful then I believed at the time.
(5) Irrespective of method, the suicide attempt was predominantly a psychotic act of young single people with chronic, severe disorders and considerable past parasuicide, in a setting of escalating self-harm.
(6) Speaking to reporters at the Pentagon, People's Liberation Army's chief of the general staff Gen Fang Fenghui also warned that the US must be objective about tensions between China and Vietnam or risk harming relations between Washington and Beijing.
(7) Jails and prison populations are unique in the incidence of deliberate self-harm, but the phenomenon is not well understood.
(8) It’s been widely reported that black people are disproportionately harmed by the mortgage market.
(9) Repeat patients were more likely to threaten to harm others, have a diagnosis of adjustment disorder, conduct or oppositional disorder and be under the care of a child welfare agency.
(10) Considerations of different ways of obtaining informed consent, determining ways of minimizing harm, and justifications for violating the therapeutic obligation are discussed but found unsatisfactory in many respects.
(11) Judge John Burgess told the men that their intention was “to do great harm in a peaceful community”.
(12) Lack of transparency about the nature of the relationship between police and media also led to speculation and perceptions, whatever the facts, that caused "serious harm".
(13) The problem of the achondroplast arises when his surroundings, right from the start, reject his disorder, connoting it with destructive anxiety: this seriously harms the subject's physical image, making him an outcast.
(14) Religious efforts to address the issue have also been complicit in absolving men of their crimes, objectifying women and doing more harm than good with campaigns that blame women for the phenomenon.
(15) Both the observance of occupational limit-values for dusts and other harmful materials at the work place, which have effects on the respiration system, and the medical survey of workers with the use of special methods for examination of respiratory system are necessary.
(16) Changes in the fitness of harmful mutations may therefore impose a greater long-term disadvantage on asexual populations than those which are sexual.
(17) The possibility of being liable if an incompetent student becomes registered and causes harm is also discussed.
(18) Butler was convicted of grevious bodily harm and child cruelty, and sentenced to prison.
(19) Was the Dalkon Shield so harmful in the nulliparous woman?
(20) Education can increase compliance and sometimes modify harmful behavior.