(a.) Unpleasant and repulsive to the sensibilities; austere; crabbed; morose; abusive; abusive; severe; rough.
(a.) Having violent contrasts of color, or of light and shade; lacking in harmony.
Example Sentences:
(1) Federal judges who blocked the bans cited harsh rhetoric employed by Trump on the campaign trail , specifically a pledge to ban all Muslims from entering the US and support for giving priority to Christian refugees, as being reflective of the intent behind his travel ban.
(2) The first problem facing Calderdale is sheep-rustling Happy Valley – filmed around Hebden Bridge, with its beautiful stone houses straight off the pages of the Guardian’s Lets Move To – may be filled with rolling hills and verdant pastures, but the reality of rural issues are harsh.
(3) On referral to our clinic, his physical examination and tape recording were characterized by harsh inspiratory stridor.
(4) There are harsh lessons in football and we have learned some over the last week.” Two James Milner penalties and goals from the impressive Adam Lallana, Sadio Mané and Philippe Coutinho took Liverpool’s tally to 24 in eight games.
(5) The tougher external environment in 2015 means that our businesses and functions need to work … to take a number of measures in response to the harsh trading environment,” Dudley said, according to a memo reported by Reuters.
(6) I couldn't shake the harsh words from my head and worried about if, or when, they would spill over into real life.
(7) A former senior CIA official said the secretary of state at the time, Colin Powell, eventually was informed about the program and sat in meetings in which harsh interrogation techniques were discussed.
(8) The results indicate the presence of carbohydrate epitopes buried within collagenous polypeptides that are exposed by harsh denaturing conditions.
(9) Official papers released by the National Archives show that the "wets" – notably Jim Prior, Peter Walker, Ian Gilmour, Mark Carlisle, Lord Soames and Francis Pym – were able to demonstrate that a majority of the cabinet rejected as unnecessarily harsh Sir Geoffrey Howe's demands for further public spending cuts and tax cuts.
(10) We report a case of a 17 year old boy who was referred for evaluation of a large anterior mediastinal mass, causing dyspnea and cough and resulting in a harsh systolic murmur.
(11) I appeal to the king of Saudi Arabia to exercise his power to halt the public flogging by pardoning Mr Badawi, and to urgently review this type of extraordinarily harsh penalty.” Badawi’s case was one of several recent prosecutions of activists.
(12) • Very robust questioning, known as the harsh approach, could be banned – or if not "the approach should not include an analogy with a military drill sergeant".
(13) He said he did not oppose the criminalisation of homosexuality but said imprisonment and the death penalty are too harsh.
(14) Fellow opposition activists and sympathisers took the harsh sentence as a sign that heavy jail terms awaited the rest.
(15) Pledge news: harsh • 26 Jan , Darragh MacAnthony, Peterborough chairman on the "incredibly harsh" abuse by fans of manager Mark Cooper: "Nobody has given the bloke a chance.
(16) But initial fan reaction to the first teaser trailers was harsh.
(17) The probability of skin-galvanic reaction appearance was harshly decreased.
(18) Offshore detention with increased isolation in remote and harsh circumstances exaggerates that adversity.
(19) Pictures of the concentration camps served to reinforce the necessity of the war and its unavoidably harsh economic legacy.
(20) If you're in doubt of the impact this can have, "brand imagery" studies show that when participants smoke the exact same cigarettes presented in lighter coloured packs, or in packs with "mild" in the name, they rate the smoke as lighter and less harsh, simply through the power of suggestion.
(1) Based on these results, we concluded that the inhibition of putrefactive anaerobe 3679 by sorbate resulted from a stringent-type regulatory response induced by the protonophoric activity of sorbic acid.
(2) The kinetics of extracellular neutral proteinase synthesis by an isogenic stringent (IS58) and a relaxed (IS56) strain of B. subtilis were compared.
(3) The mutation in the ilvA gene decreases the activity of threonine deaminase, and thus results in partial isoleucine auxotrophy, and finally, the reversion in the relA gene restores the stringent amino acid control of RNA synthesis in threonine producer cells.
(4) Birol said that the concerns around fracking should lead companies to adopt more stringent safety and environmental measures.
(5) Stringent (rel+) as well as relaxed (rel minus) strains were able to rapidly curtail their accumulation of ribonculeic acid (RNA) after a downshift imposed by decreasing glucose transport into the cell.
(6) With these stringent criteria the rejection rate was 71.0% for group A records, 58.5% for group B and 44.5% for group C. The proportions of records with peak quality (no missing leads or clipping, and grade 1 noise, lead drift or beat-to-beat drift) were 4.5% for group A, 5.5% for group B and 23.0% for group C. Suggested revisions in the grading of technical quality of ECGs are presented.
(7) Physicians are urged to reject involvement in rationing as inconsistent with their role as patient advocates and to support technology assessment, fee revisions, and more stringent self regulation as ways to discourage malpractice suits.
(8) During the last 21 months, 12 additional children have been managed with a more stringent protocol combining neck immobilization in a rigid cervical brace for 3 months and restriction of both contact and noncontact sports, together with a major emphasis on patient compliance.
(9) To gauge whether more stringent civil commitment criteria have led to the criminalization of mentally ill persons, forcing them into jails and prisons instead of treating them, a statewide sample of 1,226 civil commitment candidates in North Carolina was tracked for six months after their commitment hearings.
(10) Recent licensure laws have no effect on wages or employment, but older, more stringent laws sharply increase the wages and employment of skilled personnel in laboratories.
(11) One cloned fragment, PS2096, hybridized under stringent conditions to DNA of 82 P. solanacearum strains representing all subgroups of the species.
(12) The synthesis of this enzyme has previously been shown to be both growth rate dependent and stringently regulated, suggesting regulatory features similar to those of rRNA.
(13) His stringent bail conditions prohibited him from visiting the family home, and even Saltdean itself.
(14) In other respects RNA synthesis was similar to that of the enteric bacteria, being stringently controlled, inhibited by trimethoprim and continuing in the presence of chloramphenicol.
(15) In stringent ultracentrifugation procedure (12-13 X 10(6) g X min), the bulk of VA and a small portion of NA are pelleted.
(16) Poly(A,U) was cleaved rapidly, and analysis of the products of poly(A,U) hydrolysis showed a very stringent cleavage of U-A bonds.
(17) Despite this stringent matching, spread was shown to be an important prognostic variable in univariate survival analysis.
(18) In the stringent E. coli, strain 15 TAU (thymine-arginine-uracil) rel A+ (arginine), withholding thymine did not affect the rate of killing.
(19) A mutant hsp30 peptide, deleted in the amino-terminal amphiphilic helix, bound more avidly than the full-length hsp30 to mitochondria isolated from heat-shocked cells and exhibited less stringent requirements for binding.
(20) Setting more stringent targets – or at least meeting all the existing ones – would save lives.