(n.) Crushing sorrow or grief; a yielding to such grief.
Example Sentences:
(1) The Chiefs chairman and chief executive, Clark Hunt, released a statement that said: "Our thoughts and prayers remain with the families and everyone affected by the heartbreaking events of last Saturday.
(2) "The scale of the devastation is extraordinary ... and the losses are heartbreaking," he said at the White House.
(3) But what I will say is that if you are young and you are experiencing feelings of fury and heartbreak about the result, you are justified in doing so.
(4) "I hope in the future they will show a more sensitive and impartial view to those involved in such heartbreaking events and especially in the lead-up to potentially high-profile court cases."
(5) Smith herself made regular, heartbreaking, televised pleas for her children’s return.
(6) Yet ice cream does do something funny to a lot of us: it makes us nostalgic and happy and, if you take your cues from Bridget Jones, it helps us recover from heartbreak.
(7) In addition to a weaving violin and a zither that sends chills down your spine, there is a solo voice - similar to the muezzin's call from the minarets - that is full of heartbreaking longing.
(8) Forrest described the job cuts, from a workforce of about 4,500, as “personally tragic” and “heartbreaking”, but said the iron ore company was still making profits, with a break-even price of about US$39 a tonne.
(9) People deal with heartbreak in different ways, not all of them rational.
(10) Perhaps the most sensational competition debut is the 25-year-old wunderkind Xavier Dolan with his black-comedy-cum-Oedipal heartbreaker Mommy .
(11) The Spurs get revenge on their heartbreaking loss to the Miami Heat in last year's NBA Finals.
(12) In painstaking and at times horrifying detail, Alexis Jay, the professor whose inquiry investigated the sexual exploitation of children over 16 years in Rotherham , has set out the alarming scale and heartbreaking individual instances of the abuse that began in the early 1990s.
(13) There remains no legal basis for preventing the Chagossians’ return.” The broadcaster Ben Fogle, the association’s patron, said: “It’s another heartbreaking day for the Chagossian community, who have repeatedly been betrayed and abused by their own government.
(14) It was heartbreaking to lose but I was oddly happy for him because I believe in him and love him as a person.
(15) To see him bow out in such circumstances was heartbreaking, but after 126 international caps, and 74 of those as captain, he had still earned the right to walk away with his head held high.
(16) Israel News Feed (@IsraelHatzolah) HEARTBREAKING: Rosh Yeshiva Kollel Toras Moshe Rabbi Moshe Twersky HY"D killed in todays Jerusalem terror attack.
(17) "When you cheat on your partner you add to the heartbreak, pain and jealousy in the atmosphere," the website explains.
(18) That is heartbreaking, it is wrong, and no one should be treated that way in the United States of America.
(19) In this heartbreakingly beautiful country, with its engaging and resourceful people, a little prosperity and the building of a few metaphorical bridges could lead to miracles.
(20) Another of his friends, the satirist Craig Brown , once described him as moving in a world without friction, as if never having known heartbreak.
Loss
Definition:
(v. t.) The act of losing; failure; destruction; privation; as, the loss of property; loss of money by gaming; loss of health or reputation.
(v. t.) The state of losing or having lost; the privation, defect, misfortune, harm, etc., which ensues from losing.
(v. t.) That which is lost or from which one has parted; waste; -- opposed to gain or increase; as, the loss of liquor by leakage was considerable.
(v. t.) The state of being lost or destroyed; especially, the wreck or foundering of a ship or other vessel.
(v. t.) Failure to gain or win; as, loss of a race or battle.
(v. t.) Failure to use advantageously; as, loss of time.
(v. t.) Killed, wounded, and captured persons, or captured property.
(v. t.) Destruction or diminution of value, if brought about in a manner provided for in the insurance contract (as destruction by fire or wreck, damage by water or smoke), or the death or injury of an insured person; also, the sum paid or payable therefor; as, the losses of the company this year amount to a million of dollars.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) These studies, in addition to demonstrating that the placenta contains TRH deamidase activity, suggest that losses of fetal TRH through the placenta are not large.
(3) Our results indicate that increasing the delay for more than 8 days following irradiation and TCD syngeneic BMT leads to a rapid loss of the ability to achieve alloengraftment by non-TCD allogeneic bone marrow.
(4) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(5) Histological studies of nerves 2 years following irradiation demonstrated loss of axons and myelin, with a corresponding increase in endoneurial, perineurial, and epineurial connective tissue.
(6) The stages of mourning involve cognitive learning of the reality of the loss; behaviours associated with mourning, such as searching, embody unlearning by extinction; finally, physiological concomitants of grief may influence unlearning by direct effects on neurotransmitters or neurohormones, such as cortisol, ACTH, or norepinephrine.
(7) Moreover, in DCVC-treated cells the mitochondria could not be stained with rhodamine-123, indicating severe mitochondrial damage and loss of membrane potential.
(8) Adenosine diphosphate (ADP) afforded significant protection only at the very highest concentration (5.0 mM); inorganic pyrophosphate (PPi) did not protect against loss of latency at any concentration.
(9) The west Africa Ebola epidemic “Few global events match epidemics and pandemics in potential to disrupt human security and inflict loss of life and economic and social damage,” he said.
(10) Thus, it appears that neuronal loss may account for up to roughly half of the striatal D2 receptor loss during aging.
(11) Hearing loss at 8 kHz would shorten the I-V interval, while a loss at 4 kHz would be expected to lengthen the interval.
(12) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(13) With prolonged ischemia, it is only transient and is followed by a gradual loss of the adenylyl cyclase activity.
(14) A murine keratinocyte cell line that is resistant to the growth-inhibitory effects of transforming growth factor beta 1 (TGF beta 1) was examined for differential gene expression patterns that may be related to the mechanism of the loss of TGF beta 1 responsiveness.
(15) Periodontal disease activity is defined clinically by progressive loss of probing attachment and radiographically by progressive loss of alveolar bone.
(16) But not only did it post a larger loss than expected, Amazon also projected 7% to 18% revenue growth over the busiest shopping period of the year, a far cry from the 20%-plus pace that had convinced investors to overlook its persistent lack of profit in the past.
(17) The findings confirm and quantitate the severe atrophy of the neostriatum, in addition to demonstrating a severe loss of cerebral cortex and subcortical white matter in HD.
(18) We could do with similar action to cut out botnets and spam, but there aren't any big-money lobbyists coming to Mandelson pleading loss of business through those.
(19) The triad of epigastric pain unrelieved by antacids, bilious vomiting, and weight loss, particularly after a gastric operation should make one suspect this syndrome.
(20) The temporary loss of a family member through deployment brings unique stresses to a family in three different stages: predeployment, survival, and reunion.