(n.) An uneasy, burning sensation in the stomach, often attended with an inclination to vomit. It is sometimes idiopathic, but is often a symptom of often complaints.
Example Sentences:
(1) Nausea and heartburn occurred in 3 cases only and were controlled by reducing the dosage.
(2) A 62-year-old man with severe heartburn and persistent hiccups despite numerous diagnostic tests and therapeutic drug trials presented to our clinic.
(3) We speculate that hormone-related impairment of distal oesophageal clearance mechanisms may have a crucial bearing on whether heartburn develops in those individuals at greatest risk.
(4) Heartburn was induced by a meal consisting of chili, black coffee, and a spicy tomato drink mix.
(5) Heartburn was the most common symptom, more frequent in females than in males (p less than 0.01).
(6) Primary symptoms include dysphagia, odynophagia, heartburn and central chest pain.
(7) Symptoms of heartburn, regurgitation, and dysphagia were absent or minimal in most patients.
(8) The occurrence of heartburn did not correlate with the extent of reflux in the pH study.
(9) However, onions significantly increased all measures in heartburn subjects, compared with the no-onion condition, and compared with normals under the onion condition.
(10) Heartburn and epigastric pain, monitored every other week, were significantly relieved by both treatments, but to a significantly greater extent (70% vs 20% on average, p less than 0.01) and significantly faster (p less than 0.01) in the presence of triletide.
(11) 90 patients living more than 3 months complained of the following: heartburn, 18 (20%); reflux, 12 (13.3%); retrosternal pain, 3 (3.3%); stenotic sensation, 23 (25.6%); diarrhea, 10 (11.1%); abdominal pain, 14 (15.6%); and dumping syndrome, 6 (6.7%).
(12) Only ranitidine significantly reduced heartburn frequency and severity.
(13) 1) Symptom relief: Cisapride, usually at a dose of 10 mg t.i.d., was superior to placebo and metoclopramide in relief of daytime and night-time heartburn and regurgitation.
(14) Although heartburn, thought to indicate reflux of gastric contents into the oesophagus, occurs frequently in pregnant women during the last trimester, its aetiology is not clear.
(15) No patient experienced symptoms while swallowing water but one complained of heartburn and one developed symptomatic oesophageal 'spasm' during eating.
(16) Six subjects had mild subjective side effects after zindotrine (headache, dizziness, vertigo, flushing, and heartburn) compared with one report of lightheadedness after placebo.
(17) Logistic regression analysis showed increased risk of suffering heartburn with increasing gestational age (P < 0.0001), pre-pregnancy heartburn (P < 0.0001), parity (P < 0.0001) and inversely with maternal age (P < 0.05) but not with body mass index before pregnancy, race, or weight gain in pregnancy.
(18) Patients with gastroesophageal reflux often describe heartburn after "spicy meals."
(19) Heartburn, the most common presenting symptom, was abolished in 85.5% and epigastric pain in 84.6% of patients.
(20) Despite randomization of endoscopically normal patients, those treated with ranitidine had significantly more heartburn at baseline.
Pyrosis
Definition:
(n.) See Water brash, under Brash.
Example Sentences:
(1) Twice daily the patients recorded the number of episodes of retrosternal pain, regurgitation, and pyrosis on a diary card during a trial period of 1 week and during the 1st and 5th study week.
(2) The clinical course of a patient with pyrosis and intractable hiccups is presented.
(3) Preexisting esophageal or gastric disorders were present in 50% of those with esophageal obstruction, including peptic stricture, pyrosis, hiatal hernia, esophagitis, gastric stapling procedure, Schatzki ring, and muscular dystrophy.
(4) Its presence was suggested clinically by the symptoms (pyrosis, dysphagia, acid regurgitations) and confirmed in 5 patients by the barium examination in Trendelenburg and in the remainder of 10 by the esophageal pH, determination of gastroesophageal motility and endoscopic examination.
(5) 1 patient decided to discontinue the trial because of gastric pyrosis while taking the active drug.
(6) A 57-year-old white man presenting frequent recurrent chest and precordial pain, heartburn (pyrosis) and post-prandial vomiting for the previous 33 years (one to two years after Bilroth II gastrectomy) was submitted to cardiovascular, endoscopic, radiologic and biochemical studies with negative results.
(7) Continuous poor appetite and pyrosis were reported by about 5% of subjects.
(8) Pyrosis is mentioned in the literature as present in 40% of the cases, but it is considered mainly as symptom of coexistent hiatal hernia.
(9) Antacids are often the first therapeutic approach in patients with pyrosis.
(10) Side effects were encountered in 3 patients treated with naproxene (2 cases of epigastralgia and pyrosis and 1 case of dyspnea so marked as to require suspension of treatment) and in 3 treated with DAR (modest diarrhea).
(11) All 12 patients had complete resolution of pyrosis and healed esophagitis by six months, but no significant endoscopic regression was observed in the extent of Barrett's epithelium.
(12) Tolerance to the drug was, however, satisfactory; nausea, pyrosis, and vomiting were the only frequent side effects.
(13) Twelve of them had gastroesophageal reflux (GER) manifested by either digestive (vomiting, dysphagia, pyrosis, haemorrhage or foreign body impaction) or respiratory symptoms (repeated neumoniae or frequent u.r.i.).
(14) This open trial was conducted in 50 pregnant women, presenting during the 2nd and 3rd trimesters of their pregnancy typical symptoms of gastro-esophageal reflux (pyrosis, regurgitations, retro-sternal burning sensations, dyspepsia, epigastric burning).
(15) Pyrosis, epigastric pain, sense of epigastric repletion and foul-tasting mouth were considered on a scale from 0 to 4 attributed by the patient.
(16) Due to insufficient casual therapy of oral symptoms of dyniae and pyrosis, we applied infrared soft laser in treatment of patients with those oral symptoms.
(17) In 5 patients the following side effects occurred: 2 cases of allergic exanthema, 2 cases of mild diarrhoe and 1 case of pyrosis.
(18) All patients with Barrett's esophagus had pyrosis and 31 of the 42 patients had erosive esophagitis.
(19) Slight and transient episodes of pyrosis or epigastric pain represented the great majority of S.E.
(20) epigastric pain, pyrosis, nausea, vomiting and headache.