(superl.) Heaved or lifted with labor; not light; weighty; ponderous; as, a heavy stone; hence, sometimes, large in extent, quantity, or effects; as, a heavy fall of rain or snow; a heavy failure; heavy business transactions, etc.; often implying strength; as, a heavy barrier; also, difficult to move; as, a heavy draught.
(superl.) Not easy to bear; burdensome; oppressive; hard to endure or accomplish; hence, grievous, afflictive; as, heavy yokes, expenses, undertakings, trials, news, etc.
(superl.) Laden with that which is weighty; encumbered; burdened; bowed down, either with an actual burden, or with care, grief, pain, disappointment.
(superl.) Slow; sluggish; inactive; or lifeless, dull, inanimate, stupid; as, a heavy gait, looks, manners, style, and the like; a heavy writer or book.
(superl.) Strong; violent; forcible; as, a heavy sea, storm, cannonade, and the like.
(superl.) Loud; deep; -- said of sound; as, heavy thunder.
(superl.) Dark with clouds, or ready to rain; gloomy; -- said of the sky.
(superl.) Impeding motion; cloggy; clayey; -- said of earth; as, a heavy road, soil, and the like.
(superl.) Not raised or made light; as, heavy bread.
(superl.) Not agreeable to, or suitable for, the stomach; not easily digested; -- said of food.
(superl.) Having much body or strength; -- said of wines, or other liquors.
(superl.) With child; pregnant.
(adv.) Heavily; -- sometimes used in composition; as, heavy-laden.
(v. t.) To make heavy.
Example Sentences:
(1) We were instantly refused entrance by the heavies at the door.
(2) With the exception of PMMA and PTFE, all plastics leave a very heavy tar- and soot deposit after burning.
(3) One-nation prime ministers like Cameron found the libertarians useful for voting against taxation; inconvenient when they got too loud about heavy-handed government.
(4) The prevalence was also higher in medium and heavy smokers.
(5) These results indicate that the inhibition of CarAc by heavy metals occurs by binding of the sulfhydryl on the enzyme by the metals.
(6) The biggest single source of air pollution is coal-fired power stations and China, with its large population and heavy reliance on coal power, provides $2.3tn of the annual subsidies.
(7) The combined evidence from immunoglobulin light chain staining and the analysis of immunoglobulin heavy chain gene rearrangement indicated that the lesions in most patients represented polyclonal proliferations that gave rise to clonal subpopulations.
(8) Variations in light chain composition, particularly fast and slow myosin light chain 1, appeared to occur independently of the variations in heavy chain composition, suggesting that some myosin molecules consist of mixtures of slow- and fast-type subunits.
(9) In general, enzyme activity was strongly reduced by heavy metal inorganic cations; less strongly by organometallic cations, some anions, and certain pesticides; and weakly inhibited by light metal cations and organometallic and organic compounds.
(10) But the condition of edifices such as B30 and B38 - and all the other "legacy" structures built at Sellafield decades ago - suggest Britain might end up paying a heavy price for this new commitment to nuclear energy.
(11) By applying this method to rat cardiac whole muscle, high-molecular weight proteins, such as myosin heavy chains, are focused on the first-dimensional gels and, in addition, minor components are resolved on the second-dimensional gels, without loss during equilibration with detergent.
(12) To identify cells of different myogenic lineages, myotubes were analyzed for content of fast and slow classes of myosin heavy chain (MHC) isoforms by immunocytochemistry and immunoblotting using specific monoclonal antibodies.
(13) Horses in heavy training may require more energy than they can consume on a conventional diet.
(14) As yet the observations demonstrate that workers exposed in their occupation to heavy metals (cadmium, lead, metalic mercury) and organic solvents should be subjected to special control for detection of renal changes.
(15) Heavy death losses (59%) occurred in adult Mystromys 3--14 days after muscle biopsies were taken from their rear legs.
(16) A comparative analysis of the structure and reactivity of the recombinant monoclonal antibodies showed that the light and heavy Ig-specific chains could form the reactive antibodies when the chains were present in different paratopes of Ig molecules.
(17) Mononucleosomes obtained from labeled cells were fractionated by rate zonal sedimentation through a sucrose gradient in heavy water (Senshu et al.
(18) Previous epitope mapping studies of human factor VIII (FVIII) inhibitor antibodies with heavy chain specificity localized epitopes to the amino-terminal half of the FVIII A2 domain.
(19) The ABI figures revealed that the best annuity for someone who is a heavy smoker and has severely impaired health was at Prudential, which paid out 46% more than the worst, from Friends Life.
(20) The parasites were highly aggregated within the study community, with most people harbouring low burdens while a few individuals harboured very heavy burdens.
Heft
Definition:
(n.) Same as Haft, n.
(n.) The act or effort of heaving/ violent strain or exertion.
(n.) Weight; ponderousness.
(n.) The greater part or bulk of anything; as, the heft of the crop was spoiled.
() of Heft
(v. t.) To heave up; to raise aloft.
(v. t.) To prove or try the weight of by raising.
Example Sentences:
(1) V-HeFT, the first mortality trial in patients with heart failure, has provided important insights regarding trial design, including patient selection and efficacy criteria.
(2) It’s the failure of an over-centralised prime ministerial office, too small to have real intellectual and research heft yet arrogant enough to overrule FCO advisers.
(3) Maybe the broader movie-going public that adds heft to a blockbuster's box office has grown tired of Middle Earth after all these years.
(4) The reduction of mortality in patients with chronic congestive heart failure treated with the vasodilator regimen hydralazine and isosorbide dinitrate compared to those treated with placebo or prazosin in the Veterans Administration Cooperative Study (V-HeFT) was examined in order to explore the possible mechanism of the favourable effect.
(5) The 5S will cost $649 (£549) without a contract, and also comes with a 10cm (4in) screen and an 8 megapixel camera – the same as the iPhone 5 – with double the processing heft of its predecessor.
(6) Outside parliament, Lib Dem party circles and his Kingston constituency, he was barely known, and he lacks both the smooth, television-friendly manners of a Cameron or Clegg, and the heft brought to parliament by those with a previous career (Davey got a job with the Liberal Democrats a few months after leaving university).
(7) That's a job for parents and teachers, the authorities with the heft and reach to alter public perceptions.
(8) Thick hunks of Heft Co sourdough are served with jam from cult LA restaurant Sqirl .
(9) The Australian Industry Group’s chief executive, Innes Willox, said the inquiry should consider “various funds established by unions and heft commissions paid to unions from insurance products purchased during bargaining” but improper behaviour by employers should also be dealt with.
(10) They spoke as one, both showing their commitment to Grangemouth and both putting their respective governmental heft behind the attempt to restart the plant.
(11) Photograph: National Trust What do you do if you hanker after a dose of solitude somewhere scenic and remote, but can no longer heft a heavy rucksack because of a dodgy back?
(12) The angiotensin converting enzyme inhibitors (ACEI) are now the cornerstone of heart failure treatment, reducing mortality in severe heart failure (CONSENSUS) and superior to standard vasodilator therapy (V-HeFT-2) at improving the survival of patients with mild to moderate heart failure.
(13) More than 100 organizations have lent their support, including the institutional heft of the American Association for the Advancement of Science , the world’s largest general scientific organization, and the American Geophysical Union.
(14) This situation highlights the challenges facing a country still recovering from the global financial crisis that began on its own soil, with fractured domestic politics that not only jeopardise its ability to govern at home but also cast doubt on its economic heft abroad.
(15) The overwhelming impression is one of tasteful reserve, of glistening cream paint and shining green and black railings – until you pause to examine the enormous heft of the houses: vast, detached palaces, with too many windows to count, on a scale dwarfing other private homes in London .
(16) As the Liberal Democrat elder statesman with most economic heft, it was for him on Monday to express the peril we stand in – and, were he free to do so, to warn of Conservative policies that gravely worsen the danger.
(17) Michael Gove will bring to their cause some intellectual heft and a talent for making a fluent case, though it is not yet clear how actively the justice secretary will campaign when he knows that an Out success would mean the destruction of his friends in Downing Street.
(18) Samsung's colossal market share in smartphones and mobile phones, for instance, is reflected in installed base figures – and also in its profits and heft in the business world.
(19) This result corresponded to an optimal relation at peak kinetic energy for the hefting.
(20) Again a number of ongoing major trials are set to establish whether these drugs reduce death in patients with chronic heart failure (V-HeFT II, SOLVD) and in patients immediately after myocardial infarction (CONSENSUS II, SAVE,.