(superl.) Heaved or lifted with labor; not light; weighty; ponderous; as, a heavy stone; hence, sometimes, large in extent, quantity, or effects; as, a heavy fall of rain or snow; a heavy failure; heavy business transactions, etc.; often implying strength; as, a heavy barrier; also, difficult to move; as, a heavy draught.
(superl.) Not easy to bear; burdensome; oppressive; hard to endure or accomplish; hence, grievous, afflictive; as, heavy yokes, expenses, undertakings, trials, news, etc.
(superl.) Laden with that which is weighty; encumbered; burdened; bowed down, either with an actual burden, or with care, grief, pain, disappointment.
(superl.) Slow; sluggish; inactive; or lifeless, dull, inanimate, stupid; as, a heavy gait, looks, manners, style, and the like; a heavy writer or book.
(superl.) Strong; violent; forcible; as, a heavy sea, storm, cannonade, and the like.
(superl.) Loud; deep; -- said of sound; as, heavy thunder.
(superl.) Dark with clouds, or ready to rain; gloomy; -- said of the sky.
(superl.) Impeding motion; cloggy; clayey; -- said of earth; as, a heavy road, soil, and the like.
(superl.) Not raised or made light; as, heavy bread.
(superl.) Not agreeable to, or suitable for, the stomach; not easily digested; -- said of food.
(superl.) Having much body or strength; -- said of wines, or other liquors.
(superl.) With child; pregnant.
(adv.) Heavily; -- sometimes used in composition; as, heavy-laden.
(v. t.) To make heavy.
Example Sentences:
(1) We were instantly refused entrance by the heavies at the door.
(2) With the exception of PMMA and PTFE, all plastics leave a very heavy tar- and soot deposit after burning.
(3) One-nation prime ministers like Cameron found the libertarians useful for voting against taxation; inconvenient when they got too loud about heavy-handed government.
(4) The prevalence was also higher in medium and heavy smokers.
(5) These results indicate that the inhibition of CarAc by heavy metals occurs by binding of the sulfhydryl on the enzyme by the metals.
(6) The biggest single source of air pollution is coal-fired power stations and China, with its large population and heavy reliance on coal power, provides $2.3tn of the annual subsidies.
(7) The combined evidence from immunoglobulin light chain staining and the analysis of immunoglobulin heavy chain gene rearrangement indicated that the lesions in most patients represented polyclonal proliferations that gave rise to clonal subpopulations.
(8) Variations in light chain composition, particularly fast and slow myosin light chain 1, appeared to occur independently of the variations in heavy chain composition, suggesting that some myosin molecules consist of mixtures of slow- and fast-type subunits.
(9) In general, enzyme activity was strongly reduced by heavy metal inorganic cations; less strongly by organometallic cations, some anions, and certain pesticides; and weakly inhibited by light metal cations and organometallic and organic compounds.
(10) But the condition of edifices such as B30 and B38 - and all the other "legacy" structures built at Sellafield decades ago - suggest Britain might end up paying a heavy price for this new commitment to nuclear energy.
(11) By applying this method to rat cardiac whole muscle, high-molecular weight proteins, such as myosin heavy chains, are focused on the first-dimensional gels and, in addition, minor components are resolved on the second-dimensional gels, without loss during equilibration with detergent.
(12) To identify cells of different myogenic lineages, myotubes were analyzed for content of fast and slow classes of myosin heavy chain (MHC) isoforms by immunocytochemistry and immunoblotting using specific monoclonal antibodies.
(13) Horses in heavy training may require more energy than they can consume on a conventional diet.
(14) As yet the observations demonstrate that workers exposed in their occupation to heavy metals (cadmium, lead, metalic mercury) and organic solvents should be subjected to special control for detection of renal changes.
(15) Heavy death losses (59%) occurred in adult Mystromys 3--14 days after muscle biopsies were taken from their rear legs.
(16) A comparative analysis of the structure and reactivity of the recombinant monoclonal antibodies showed that the light and heavy Ig-specific chains could form the reactive antibodies when the chains were present in different paratopes of Ig molecules.
(17) Mononucleosomes obtained from labeled cells were fractionated by rate zonal sedimentation through a sucrose gradient in heavy water (Senshu et al.
(18) Previous epitope mapping studies of human factor VIII (FVIII) inhibitor antibodies with heavy chain specificity localized epitopes to the amino-terminal half of the FVIII A2 domain.
(19) The ABI figures revealed that the best annuity for someone who is a heavy smoker and has severely impaired health was at Prudential, which paid out 46% more than the worst, from Friends Life.
(20) The parasites were highly aggregated within the study community, with most people harbouring low burdens while a few individuals harboured very heavy burdens.
Hefty
Definition:
(a.) Moderately heavy.
Example Sentences:
(1) Childcare carves out a hefty third of household income for one in three families, overshadowing mortgage repayments as the biggest family expenditure .
(2) There is, of course, a place for regulatory vigilance, for forcing entire institutions to clean up after themselves by paying hefty fines, and weeding out bad practices.
(3) She is now suing the French statesman in a civil court, which could result in a hefty damages award.
(4) The last time I visited they were rollerblading and after plenty of assistance managing the straps and buckles on the hefty skates, I took to the floor.
(5) But it had at its disposal a hefty deterrent: forgery was a capital offence between 1697 and 1832.
(6) If he makes the move from NYPD commissioner to Homeland Security secretary, Kelly will carry with him to Washington some very hefty baggage.
(7) Tory hedge fund and multimillionaire donors will face no similar restrictions, leaving boards free to write hefty cheques backing the Tory party.
(8) In a hard-hitting report on the countries facing macroeconomic imbalances, such as overvalued housing markets or hefty government debts, the European commission identified a total of 13 member states – including France, the Netherlands and Belgium – which it said should take urgent action to restore the health of their economies.
(9) Nine months later, the details of the scheme are yet to be agreed and Lloyds is determined to escape paying a hefty premium for the government to insure its toxic assets because it believes its losses have peaked.
(10) Pick it up and it is a surprisingly hefty bit of kit.
(11) A ustralians are routinely being told that hefty mining taxes would hinder the country’s largest exports of coal and iron ore.
(12) Oxfam's Lucy Brinicombe is blogging for the Guardian from Cancún, and here's a bit of her first post : There's an air of uncertainty here, of controlled hope mixed with a hefty dose of pragmatism compared with the heady days before last year's UN climate talks in Copenhagen, where a deadline to secure a fair, safe and legally binding climate deal came – and went.
(13) Averaged projections of the complex resemble those found for the purified PSI reaction centre after reconstitution (Ford, R.C, Hefti, A. and Engel, A.
(14) Linguistic trespassers will be prosecuted with a hefty fine.
(15) For those who like verisimilitude in their faux fags there are disposables – the hefty but effective Ten Motives or the petite, feminine NJOY – and rechargeable kits complete with USB chargers and cartridges from the likes of E-Lites, Halo and Skycig.
(16) It's probably just a fire in one of the townships.” Following Torino, Seoul and Helsinki, Cape Town is the fourth city to be awarded the title of World Design Capital, an accolade bestowed by the Montreal-based International Council for Societies of Industrial Design , which charges a hefty fee to honour a different city with its logo each year.
(17) It was certainly his best moment for the north London club after he missed a large portion of last season through injury and failed to live up to his hefty transfer fee.
(18) In animals kept on a diet with caseine the proportion of the heterohemagglutinines production and of specific antibodies had a reciprocal character, which manifested itself in a hefty depression of the agglutinines biosynthesis to sheep erythrocytes with an accruing titres of antidiphtherial antibodies.
(19) The organisers said the next generation would be more evenly split as a hefty 70% of the "ones to watch" (with just three to five years experience) were women.
(20) While small stuffed birds used to dangle from rear view mirrors – the Maltese version of fluffy dice – such displays are now rare and hunters can face hefty fines of up to €5,000 (£3,600) and jail if they are caught killing protected species.