(superl.) Heaved or lifted with labor; not light; weighty; ponderous; as, a heavy stone; hence, sometimes, large in extent, quantity, or effects; as, a heavy fall of rain or snow; a heavy failure; heavy business transactions, etc.; often implying strength; as, a heavy barrier; also, difficult to move; as, a heavy draught.
(superl.) Not easy to bear; burdensome; oppressive; hard to endure or accomplish; hence, grievous, afflictive; as, heavy yokes, expenses, undertakings, trials, news, etc.
(superl.) Laden with that which is weighty; encumbered; burdened; bowed down, either with an actual burden, or with care, grief, pain, disappointment.
(superl.) Slow; sluggish; inactive; or lifeless, dull, inanimate, stupid; as, a heavy gait, looks, manners, style, and the like; a heavy writer or book.
(superl.) Strong; violent; forcible; as, a heavy sea, storm, cannonade, and the like.
(superl.) Loud; deep; -- said of sound; as, heavy thunder.
(superl.) Dark with clouds, or ready to rain; gloomy; -- said of the sky.
(superl.) Impeding motion; cloggy; clayey; -- said of earth; as, a heavy road, soil, and the like.
(superl.) Not raised or made light; as, heavy bread.
(superl.) Not agreeable to, or suitable for, the stomach; not easily digested; -- said of food.
(superl.) Having much body or strength; -- said of wines, or other liquors.
(superl.) With child; pregnant.
(adv.) Heavily; -- sometimes used in composition; as, heavy-laden.
(v. t.) To make heavy.
Example Sentences:
(1) We were instantly refused entrance by the heavies at the door.
(2) With the exception of PMMA and PTFE, all plastics leave a very heavy tar- and soot deposit after burning.
(3) One-nation prime ministers like Cameron found the libertarians useful for voting against taxation; inconvenient when they got too loud about heavy-handed government.
(4) The prevalence was also higher in medium and heavy smokers.
(5) These results indicate that the inhibition of CarAc by heavy metals occurs by binding of the sulfhydryl on the enzyme by the metals.
(6) The biggest single source of air pollution is coal-fired power stations and China, with its large population and heavy reliance on coal power, provides $2.3tn of the annual subsidies.
(7) The combined evidence from immunoglobulin light chain staining and the analysis of immunoglobulin heavy chain gene rearrangement indicated that the lesions in most patients represented polyclonal proliferations that gave rise to clonal subpopulations.
(8) Variations in light chain composition, particularly fast and slow myosin light chain 1, appeared to occur independently of the variations in heavy chain composition, suggesting that some myosin molecules consist of mixtures of slow- and fast-type subunits.
(9) In general, enzyme activity was strongly reduced by heavy metal inorganic cations; less strongly by organometallic cations, some anions, and certain pesticides; and weakly inhibited by light metal cations and organometallic and organic compounds.
(10) But the condition of edifices such as B30 and B38 - and all the other "legacy" structures built at Sellafield decades ago - suggest Britain might end up paying a heavy price for this new commitment to nuclear energy.
(11) By applying this method to rat cardiac whole muscle, high-molecular weight proteins, such as myosin heavy chains, are focused on the first-dimensional gels and, in addition, minor components are resolved on the second-dimensional gels, without loss during equilibration with detergent.
(12) To identify cells of different myogenic lineages, myotubes were analyzed for content of fast and slow classes of myosin heavy chain (MHC) isoforms by immunocytochemistry and immunoblotting using specific monoclonal antibodies.
(13) Horses in heavy training may require more energy than they can consume on a conventional diet.
(14) As yet the observations demonstrate that workers exposed in their occupation to heavy metals (cadmium, lead, metalic mercury) and organic solvents should be subjected to special control for detection of renal changes.
(15) Heavy death losses (59%) occurred in adult Mystromys 3--14 days after muscle biopsies were taken from their rear legs.
(16) A comparative analysis of the structure and reactivity of the recombinant monoclonal antibodies showed that the light and heavy Ig-specific chains could form the reactive antibodies when the chains were present in different paratopes of Ig molecules.
(17) Mononucleosomes obtained from labeled cells were fractionated by rate zonal sedimentation through a sucrose gradient in heavy water (Senshu et al.
(18) Previous epitope mapping studies of human factor VIII (FVIII) inhibitor antibodies with heavy chain specificity localized epitopes to the amino-terminal half of the FVIII A2 domain.
(19) The ABI figures revealed that the best annuity for someone who is a heavy smoker and has severely impaired health was at Prudential, which paid out 46% more than the worst, from Friends Life.
(20) The parasites were highly aggregated within the study community, with most people harbouring low burdens while a few individuals harboured very heavy burdens.
Huge
Definition:
(superl.) Very large; enormous; immense; excessive; -- used esp. of material bulk, but often of qualities, extent, etc.; as, a huge ox; a huge space; a huge difference.
Example Sentences:
(1) Handing Greater Manchester’s £6bn health and social care budget over to the city’s combined authority is the most exciting experiment in local government and the health service in decades – but the risks are huge.
(2) The Pan American Health Organization, the Americas arm of the World Health Organization, estimated the deaths from Tuesday's magnitude 7 quake at between 50,000 and 100,000, but said that was a "huge guess".
(3) Even if it were not the case that police use a variety of tricks to keep recorded crime figures low, this data would still represent an almost meaningless measure of the extent of crime in society, for the simple reason that a huge proportion of crimes (of almost all sorts) have always gone unreported.
(4) To many he was a rockstar, to me he was simply 'Dad', and I loved him hugely.
(5) The matter is now in the hands of the Guernsey police and the law officers.” One resident who is a constant target of the paper and has complained to police, Rosie Guille, said the allegations had a “huge impact on morale” on the island.
(6) "We have peace in Sierra Leone now, and Tony Blair made a huge contribution to that," said Warrant Officer Abu Bakerr Kamara.
(7) The size of Florida makes the kind of face-to-face politics of the earlier contests impossible, requiring instead huge ad spending.
(8) To augment the in vitro expansion of LAK cells, we added highly purified human recombinant interleukin-2, phytohemagglutinin and accessory cells (Uc cells) to the LAK culture system, with which huge number of LAK cells (LAK-L) were generated from originally small number of peripheral blood lymphocytes of cancer patients.
(9) The difference in Brazil will be the huge distances involved, with the crazy decision not to host the group stages in geographical clusters leading to logistical and planning nightmares.
(10) We are in the middle of the third year of huge cuts in acute hospitals' budgets," said Porter.
(11) While there has been almost no political reform during their terms of office, there have been several ambitious steps forward in terms of environmental policy: anti-desertification campaigns; tree planting; an environmental transparency law; adoption of carbon targets; eco-services compensation; eco accounting; caps on water; lower economic growth targets; the 12th Five-Year Plan; debate and increased monitoring of PM2.5 [fine particulate matter] and huge investments in eco-cities, "clean car" manufacturing, public transport, energy-saving devices and renewable technology.
(12) But it is a huge logistical problem – unique in the world.
(13) It may not point to independence – nor, given that large swaths of Wales remain firmly dominated by Labour, mean any huge advance for Plaid Cymru.
(14) Half a million homes were sold in Scotland, we lost a huge, huge chunk of stock, and as house prices began to escalate so any asset to the community has gone.
(15) There must also be strict rules in place to reduce the risks they take with shareholders' funds.Yet the huge cost of increasing capital and liquidity is forgotten when the Treasury urges them to increase lending to small and medium businesses.
(16) Toxicity has been reported in the fetus of a woman ingesting a huge overdose of digitoxin; the same result would be anticipated with digoxin poisoning.
(17) All became highly managed, "domesticated" landscapes that demanded a huge input of labour to build and maintain.
(18) Fine, but the most important new political fact is the unprecedented wave of support that has latched on to Corbyn: the hundreds of thousands who joined Labour, the thumping majority that handed him the leadership, the huge sections of the country that have tuned out of Westminster droid-talk.
(19) Calum MacLean, Grangemouth Petrochemicals chairman, says, “This is a hugely sad day for everyone at Grangemouth.
(20) I’m so happy to be joining Arsenal, a club which has a great manager, a fantastic squad of players, huge support around the world and a great stadium in London,” said Sánchez.